Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 44FADSequence analysisAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:PA3584
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3584.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001261041 – 512Glycerol-3-phosphate dehydrogenaseAdd BLAST512

Proteomic databases

PaxDbiP52111.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3584.

Structurei

3D structure databases

ProteinModelPortaliP52111.
SMRiP52111.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C6V. Bacteria.
COG0578. LUCA.
HOGENOMiHOG000004811.
InParanoidiP52111.
KOiK00111.
OMAiPWVAKFI.
PhylomeDBiP52111.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
InterProiIPR031656. DAO_C.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF16901. DAO_C. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SUPFAMiSSF51905. SSF51905. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQAHTPSAP LAEVYDVAVV GGGINGVGIA ADAAGRGLSV FLCEQHDLAQ
60 70 80 90 100
HTSSASSKLI HGGLRYLEHY EFRLVREALA EREVLLAKAP HIVKPLRFVL
110 120 130 140 150
PHRPHLRPAW MIRAGLFLYD HLGKREKLPA SRGLRFTGSS PLKAEIRRGF
160 170 180 190 200
EYSDCAVDDA RLVVLNAISA REHGAHVHTR TRCVSARRSK GLWHLHLERS
210 220 230 240 250
DGSLYSIRAR ALVNAAGPWV ARFIQDDLKQ KSPYGIRLIQ GSHIIVPKLY
260 270 280 290 300
EGEHAYILQN EDRRIVFAIP YLDRFTMIGT TDREYQGDPA KVAISEEETA
310 320 330 340 350
YLLQVVNAHF KQQLAAADIL HSFAGVRPLC DDESDEPSAI TRDYTLSLSA
360 370 380 390 400
GNGEPPLLSV FGGKLTTYRK LAESALTQLQ PFFANLGPAW TAKAPLPGGE
410 420 430 440 450
QMQSVEALTE QLANRYAWLD RELALRWART YGTRVWRLLD GVNGEADLGE
460 470 480 490 500
HLGGGLYARE VDYLCKHEWA QDAEDILWRR SKLGLFLSPS QQVRLGQYLQ
510
SEHPHRPRVH AA
Length:512
Mass (Da):57,135
Last modified:December 8, 2000 - v2
Checksum:iDFF734821ABD730C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti77 – 78EA → DT in AAA81584 (PubMed:8157588).Curated2
Sequence conflicti133 – 140GLRFTGSS → ACVHRQQ in AAA81584 (PubMed:8157588).Curated8
Sequence conflicti180 – 208RTRCV…LYSIR → APAASAPVAARDSGTCTWSA ATAACIRS in AAA81584 (PubMed:8157588).CuratedAdd BLAST29
Sequence conflicti425 – 430LRWART → PALGAH in AAA81584 (PubMed:8157588).Curated6

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06231 Genomic DNA. Translation: AAA81584.1.
AE004091 Genomic DNA. Translation: AAG06972.1.
PIRiA55207.
B83197.
RefSeqiNP_252274.1. NC_002516.2.
WP_003098460.1. NZ_ASJY01000584.1.

Genome annotation databases

EnsemblBacteriaiAAG06972; AAG06972; PA3584.
GeneIDi880179.
KEGGipae:PA3584.
PATRICi19841787. VBIPseAer58763_3751.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06231 Genomic DNA. Translation: AAA81584.1.
AE004091 Genomic DNA. Translation: AAG06972.1.
PIRiA55207.
B83197.
RefSeqiNP_252274.1. NC_002516.2.
WP_003098460.1. NZ_ASJY01000584.1.

3D structure databases

ProteinModelPortaliP52111.
SMRiP52111.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3584.

Proteomic databases

PaxDbiP52111.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06972; AAG06972; PA3584.
GeneIDi880179.
KEGGipae:PA3584.
PATRICi19841787. VBIPseAer58763_3751.

Organism-specific databases

PseudoCAPiPA3584.

Phylogenomic databases

eggNOGiENOG4105C6V. Bacteria.
COG0578. LUCA.
HOGENOMiHOG000004811.
InParanoidiP52111.
KOiK00111.
OMAiPWVAKFI.
PhylomeDBiP52111.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
InterProiIPR031656. DAO_C.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF16901. DAO_C. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SUPFAMiSSF51905. SSF51905. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLPD_PSEAE
AccessioniPrimary (citable) accession number: P52111
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 8, 2000
Last modified: November 2, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.