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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 44FADSequence analysisAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processGlycerol metabolism
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-3653-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:PA3584
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3584

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001261041 – 512Glycerol-3-phosphate dehydrogenaseAdd BLAST512

Proteomic databases

PaxDbiP52111

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3584

Structurei

3D structure databases

ProteinModelPortaliP52111
SMRiP52111
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C6V Bacteria
COG0578 LUCA
HOGENOMiHOG000004811
InParanoidiP52111
KOiK00111
OMAiVPYYWVG
PhylomeDBiP52111

Family and domain databases

Gene3Di1.10.8.870, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR031656 DAO_C
IPR038299 DAO_C_sf
IPR006076 FAD-dep_OxRdtase
IPR036188 FAD/NAD-bd_sf
IPR000447 G3P_DH_FAD-dep
PANTHERiPTHR11985 PTHR11985, 1 hit
PfamiView protein in Pfam
PF01266 DAO, 1 hit
PF16901 DAO_C, 1 hit
PRINTSiPR01001 FADG3PDH
SUPFAMiSSF51905 SSF51905, 1 hit
PROSITEiView protein in PROSITE
PS00977 FAD_G3PDH_1, 1 hit
PS00978 FAD_G3PDH_2, 1 hit

Sequencei

Sequence statusi: Complete.

P52111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQAHTPSAP LAEVYDVAVV GGGINGVGIA ADAAGRGLSV FLCEQHDLAQ
60 70 80 90 100
HTSSASSKLI HGGLRYLEHY EFRLVREALA EREVLLAKAP HIVKPLRFVL
110 120 130 140 150
PHRPHLRPAW MIRAGLFLYD HLGKREKLPA SRGLRFTGSS PLKAEIRRGF
160 170 180 190 200
EYSDCAVDDA RLVVLNAISA REHGAHVHTR TRCVSARRSK GLWHLHLERS
210 220 230 240 250
DGSLYSIRAR ALVNAAGPWV ARFIQDDLKQ KSPYGIRLIQ GSHIIVPKLY
260 270 280 290 300
EGEHAYILQN EDRRIVFAIP YLDRFTMIGT TDREYQGDPA KVAISEEETA
310 320 330 340 350
YLLQVVNAHF KQQLAAADIL HSFAGVRPLC DDESDEPSAI TRDYTLSLSA
360 370 380 390 400
GNGEPPLLSV FGGKLTTYRK LAESALTQLQ PFFANLGPAW TAKAPLPGGE
410 420 430 440 450
QMQSVEALTE QLANRYAWLD RELALRWART YGTRVWRLLD GVNGEADLGE
460 470 480 490 500
HLGGGLYARE VDYLCKHEWA QDAEDILWRR SKLGLFLSPS QQVRLGQYLQ
510
SEHPHRPRVH AA
Length:512
Mass (Da):57,135
Last modified:December 8, 2000 - v2
Checksum:iDFF734821ABD730C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti77 – 78EA → DT in AAA81584 (PubMed:8157588).Curated2
Sequence conflicti133 – 140GLRFTGSS → ACVHRQQ in AAA81584 (PubMed:8157588).Curated8
Sequence conflicti180 – 208RTRCV…LYSIR → APAASAPVAARDSGTCTWSA ATAACIRS in AAA81584 (PubMed:8157588).CuratedAdd BLAST29
Sequence conflicti425 – 430LRWART → PALGAH in AAA81584 (PubMed:8157588).Curated6

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06231 Genomic DNA Translation: AAA81584.1
AE004091 Genomic DNA Translation: AAG06972.1
PIRiA55207
B83197
RefSeqiNP_252274.1, NC_002516.2
WP_003098460.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG06972; AAG06972; PA3584
GeneIDi880179
KEGGipae:PA3584
PATRICifig|208964.12.peg.3751

Similar proteinsi

Entry informationi

Entry nameiGLPD_PSEAE
AccessioniPrimary (citable) accession number: P52111
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 8, 2000
Last modified: March 28, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health