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Protein

Transcriptional regulatory protein RstA

Gene

rstA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Member of the two-component regulatory system RstB/RstA.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi136 – 235OmpR/PhoB-typePROSITE-ProRule annotationAdd BLAST100

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation, Two-component regulatory system

Enzyme and pathway databases

BioCyciEcoCyc:RSTA-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein RstA
Gene namesi
Name:rstA
Synonyms:urpT
Ordered Locus Names:b1608, JW1600
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13190. rstA.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000812231 – 239Transcriptional regulatory protein RstAAdd BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei524-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by RstB.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP52108.
PRIDEiP52108.

Expressioni

Inductioni

Induced by low extracellular levels of magnesium via the PhoQ/PhoP two-component regulatory system.1 Publication

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
kdpEP218662EBI-558990,EBI-6403634

Protein-protein interaction databases

BioGridi4261763. 6 interactors.
DIPiDIP-10807N.
IntActiP52108. 12 interactors.
MINTiMINT-1274913.
STRINGi316385.ECDH10B_1741.

Structurei

3D structure databases

ProteinModelPortaliP52108.
SMRiP52108.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 116Response regulatoryPROSITE-ProRule annotationAdd BLAST114

Phylogenomic databases

eggNOGiENOG4107EXC. Bacteria.
COG0745. LUCA.
HOGENOMiHOG000034819.
InParanoidiP52108.
KOiK07661.
PhylomeDBiP52108.

Family and domain databases

CDDicd00156. REC. 1 hit.
cd00383. trans_reg_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR001867. OmpR/PhoB-type_DNA-bd.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS51755. OMPR_PHOB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

P52108-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTIVFVEDD AEVGSLIAAY LAKHDMQVTV EPRGDQAEET ILRENPDLVL
60 70 80 90 100
LDIMLPGKDG MTICRDLRAK WSGPIVLLTS LDSDMNHILA LEMGACDYIL
110 120 130 140 150
KTTPPAVLLA RLRLHLRQNE QATLTKGLQE TSLTPYKALH FGTLTIDPIN
160 170 180 190 200
RVVTLANTEI SLSTADFELL WELATHAGQI MDRDALLKNL RGVSYDGLDR
210 220 230
SVDVAISRLR KKLLDNAAEP YRIKTVRNKG YLFAPHAWE
Length:239
Mass (Da):26,704
Last modified:June 26, 2007 - v2
Checksum:i409A1B3A2588A77D
GO

Sequence cautioni

The sequence AAA82081 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA15346 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41101 Genomic DNA. Translation: AAA82081.1. Different initiation.
U00096 Genomic DNA. Translation: AAC74680.2.
AP009048 Genomic DNA. Translation: BAA15346.1. Different initiation.
PIRiB64917.
RefSeqiNP_416125.2. NC_000913.3.
WP_001092508.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74680; AAC74680; b1608.
BAA15346; BAA15346; BAA15346.
GeneIDi946199.
KEGGiecj:JW1600.
eco:b1608.
PATRICifig|1411691.4.peg.654.

Similar proteinsi

Entry informationi

Entry nameiRSTA_ECOLI
AccessioniPrimary (citable) accession number: P52108
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: June 26, 2007
Last modified: August 30, 2017
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene