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Protein

Curli assembly protein CsgC

Gene

csgC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity).By similarity

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciEcoCyc:G6548-MONOMER.
ECOL316407:JW1026-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Curli assembly protein CsgC
Gene namesi
Name:csgC
Ordered Locus Names:b1043, JW1026
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13414. csgC.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 88Sequence analysis
Chaini9 – 110102Curli assembly protein CsgCPRO_0000021013Add
BLAST

Proteomic databases

PaxDbiP52107.

Expressioni

Inductioni

Under control of the CsgD transcription factor, part of the csgBAC/ymdA operon.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi511145.b1043.

Structurei

3D structure databases

ProteinModelPortaliP52107.
SMRiP52107. Positions 11-105.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CsgC/AgfC family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105RK8. Bacteria.
ENOG4111VMB. LUCA.
HOGENOMiHOG000118962.
KOiK04336.
OMAiLSQQWPS.

Family and domain databases

InterProiIPR014491. Curli_production_prot_CsgC.
[Graphical view]
PfamiPF10610. Tafi-CsgC. 1 hit.
[Graphical view]
PIRSFiPIRSF018100. CsgC. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52107-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTLLLLAAL SSQITFNTTQ QGDVYTIIPE VTLTQSCLCR VQILSLREGS
60 70 80 90 100
SGQSQTKQEK TLSLPANQPI ALTKLSLNIS PDDRVKIVVT VSDGQSLHLS
110
QQWPPSSEKS
Length:110
Mass (Da):11,967
Last modified:October 1, 1996 - v1
Checksum:iFD84CFB9C082CEE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X90754 Genomic DNA. Translation: CAA62283.1.
U00096 Genomic DNA. Translation: AAC74127.1.
AP009048 Genomic DNA. Translation: BAA35833.1.
PIRiS70789.
RefSeqiNP_415561.1. NC_000913.3.
WP_001094300.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74127; AAC74127; b1043.
BAA35833; BAA35833; BAA35833.
GeneIDi945623.
KEGGiecj:JW1026.
eco:b1043.
PATRICi32117323. VBIEscCol129921_1084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X90754 Genomic DNA. Translation: CAA62283.1.
U00096 Genomic DNA. Translation: AAC74127.1.
AP009048 Genomic DNA. Translation: BAA35833.1.
PIRiS70789.
RefSeqiNP_415561.1. NC_000913.3.
WP_001094300.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP52107.
SMRiP52107. Positions 11-105.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi511145.b1043.

Proteomic databases

PaxDbiP52107.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74127; AAC74127; b1043.
BAA35833; BAA35833; BAA35833.
GeneIDi945623.
KEGGiecj:JW1026.
eco:b1043.
PATRICi32117323. VBIEscCol129921_1084.

Organism-specific databases

EchoBASEiEB3190.
EcoGeneiEG13414. csgC.

Phylogenomic databases

eggNOGiENOG4105RK8. Bacteria.
ENOG4111VMB. LUCA.
HOGENOMiHOG000118962.
KOiK04336.
OMAiLSQQWPS.

Enzyme and pathway databases

BioCyciEcoCyc:G6548-MONOMER.
ECOL316407:JW1026-MONOMER.

Miscellaneous databases

PROiP52107.

Family and domain databases

InterProiIPR014491. Curli_production_prot_CsgC.
[Graphical view]
PfamiPF10610. Tafi-CsgC. 1 hit.
[Graphical view]
PIRSFiPIRSF018100. CsgC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCSGC_ECOLI
AccessioniPrimary (citable) accession number: P52107
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.