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Protein

Ferredoxin YfhL

Gene

yfhL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.Curated

Cofactori

[4Fe-4S] cluster1 PublicationNote: Binds 2 [4Fe-4S] cluster.1 Publication

Redox potential

E0 is -675 mV for the cluster 1, and -418 mV for the cluster 2.1 Publication

Manual assertion based on experiment ini

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Iron-sulfur 1 (4Fe-4S)Combined sources1 Publication1
Metal bindingi12Iron-sulfur 1 (4Fe-4S)Combined sources1 Publication1
Metal bindingi15Iron-sulfur 1 (4Fe-4S)Combined sources1 Publication1
Metal bindingi19Iron-sulfur 2 (4Fe-4S)Combined sources1 Publication1
Metal bindingi38Iron-sulfur 2 (4Fe-4S)Combined sources1 Publication1
Metal bindingi41Iron-sulfur 2 (4Fe-4S)Combined sources1 Publication1
Metal bindingi50Iron-sulfur 2 (4Fe-4S)Combined sources1 Publication1
Metal bindingi54Iron-sulfur 1 (4Fe-4S)Combined sources1 Publication1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7346-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin YfhLCurated
Alternative name(s):
EcFd1 Publication
Gene namesi
Name:yfhL
Ordered Locus Names:b2562, JW2546
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13215 yfhL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001593001 – 86Ferredoxin YfhLAdd BLAST86

Proteomic databases

PaxDbiP52102
PRIDEiP52102

Interactioni

Protein-protein interaction databases

BioGridi4260595, 11 interactors
IntActiP52102, 12 interactors
STRINGi316385.ECDH10B_2730

Structurei

Secondary structure

186
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 5Combined sources3
Turni14 – 18Combined sources5
Beta strandi28 – 30Combined sources3
Helixi35 – 37Combined sources3
Turni40 – 44Combined sources5
Helixi49 – 53Combined sources5
Beta strandi59 – 61Combined sources3
Helixi69 – 80Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZVSX-ray1.65A/B/C2-86[»]
ProteinModelPortaliP52102
SMRiP52102
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP52102

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 294Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST29
Domaini31 – 654Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105K5D Bacteria
COG1145 LUCA
HOGENOMiHOG000044615
InParanoidiP52102
OMAiDCCVPDD
PhylomeDBiP52102

Family and domain databases

InterProiView protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
PfamiView protein in Pfam
PF00037 Fer4, 1 hit
PROSITEiView protein in PROSITE
PS00198 4FE4S_FER_1, 1 hit
PS51379 4FE4S_FER_2, 2 hits

Sequencei

Sequence statusi: Complete.

P52102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLITKKCI NCDMCEPECP NEAISMGDHI YEINSDKCTE CVGHYETPTC
60 70 80
QKVCPIPNTI VKDPAHVETE EQLWDKFVLM HHADKI
Length:86
Mass (Da):9,791
Last modified:October 1, 1996 - v1
Checksum:i202CFFA35FEA15DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36841 Genomic DNA Translation: AAA79824.1
U00096 Genomic DNA Translation: AAC75615.1
AP009048 Genomic DNA Translation: BAE76738.1
PIRiA65034
RefSeqiNP_417057.1, NC_000913.3
WP_001196283.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75615; AAC75615; b2562
BAE76738; BAE76738; BAE76738
GeneIDi947031
KEGGiecj:JW2546
eco:b2562
PATRICifig|1411691.4.peg.4172

Similar proteinsi

Entry informationi

Entry nameiYFHL_ECOLI
AccessioniPrimary (citable) accession number: P52102
Secondary accession number(s): Q2MAG8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 25, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health