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Protein

Uncharacterized HTH-type transcriptional regulator YgfI

Gene

ygfI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi21 – 4020H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
  • regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7518-MONOMER.
ECOL316407:JW5476-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YgfI
Gene namesi
Name:ygfI
Ordered Locus Names:b2921, JW5476
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12974. ygfI.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Uncharacterized HTH-type transcriptional regulator YgfIPRO_0000105794Add
BLAST

Proteomic databases

PaxDbiP52044.

Interactioni

Protein-protein interaction databases

BioGridi4263514. 19 interactions.
STRINGi511145.b2921.

Structurei

3D structure databases

ProteinModelPortaliP52044.
SMRiP52044. Positions 6-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6161HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105DEQ. Bacteria.
ENOG410XPUX. LUCA.
HOGENOMiHOG000124391.
OMAiAMLDAYM.
OrthoDBiEOG69SK82.
PhylomeDBiP52044.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52044-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIFISKKMR NFILLAQTNN IARAAEKIHM TASPFGKSIA ALEEQIGYTL
60 70 80 90 100
FTRKDNNISL NKAGQELYQK LFPVYQRLSA IDNEIHNSGR RSREIVIGID
110 120 130 140 150
NTYPTIIFDQ LISLGDKYEG VTAQPVEFSE NGVIDNLFDR QLDFIISPQH
160 170 180 190 200
VSARVQELEN LTISELPPLR LGFLVSRRYE ERQEQELLQE LPWLQMRFQN
210 220 230 240 250
RANFEAMIDA NMRPCGINPT IIYRPYSFMA KISAVERGHF LTVIPHFAWR
260 270 280 290
LVNPATLKYF DAPHRPMYMQ EYLYSIRNHR YTATMLQHIA EDRDGTSH
Length:298
Mass (Da):34,674
Last modified:November 16, 2001 - v2
Checksum:i14631042D131A27E
GO

Sequence cautioni

The sequence AAA69088.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69088.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75958.2.
AP009048 Genomic DNA. Translation: BAE76985.1.
PIRiH65076.
RefSeqiNP_417396.4. NC_000913.3.
WP_000350807.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75958; AAC75958; b2921.
BAE76985; BAE76985; BAE76985.
GeneIDi947401.
KEGGiecj:JW5476.
eco:b2921.
PATRICi32121256. VBIEscCol129921_3016.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69088.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75958.2.
AP009048 Genomic DNA. Translation: BAE76985.1.
PIRiH65076.
RefSeqiNP_417396.4. NC_000913.3.
WP_000350807.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP52044.
SMRiP52044. Positions 6-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263514. 19 interactions.
STRINGi511145.b2921.

Proteomic databases

PaxDbiP52044.

Protocols and materials databases

DNASUi947401.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75958; AAC75958; b2921.
BAE76985; BAE76985; BAE76985.
GeneIDi947401.
KEGGiecj:JW5476.
eco:b2921.
PATRICi32121256. VBIEscCol129921_3016.

Organism-specific databases

EchoBASEiEB2801.
EcoGeneiEG12974. ygfI.

Phylogenomic databases

eggNOGiENOG4105DEQ. Bacteria.
ENOG410XPUX. LUCA.
HOGENOMiHOG000124391.
OMAiAMLDAYM.
OrthoDBiEOG69SK82.
PhylomeDBiP52044.

Enzyme and pathway databases

BioCyciEcoCyc:G7518-MONOMER.
ECOL316407:JW5476-MONOMER.

Miscellaneous databases

PROiP52044.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYGFI_ECOLI
AccessioniPrimary (citable) accession number: P52044
Secondary accession number(s): Q2M9S1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 16, 2001
Last modified: January 20, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.