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Protein

Uncharacterized oxidoreductase YgfF

Gene

ygfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421SubstrateBy similarity
Active sitei156 – 1561Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi4 – 2825NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:G7514-MONOMER.
ECOL316407:JW2870-MONOMER.
RETL1328306-WGS:GSTH-3971-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YgfF (EC:1.-.-.-)
Gene namesi
Name:ygfF
Synonyms:yqfD
Ordered Locus Names:b2902, JW2870
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12971. ygfF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Uncharacterized oxidoreductase YgfFPRO_0000054836Add
BLAST

Proteomic databases

EPDiP52037.
PaxDbiP52037.

Interactioni

Protein-protein interaction databases

BioGridi4260859. 2 interactions.
DIPiDIP-12165N.
IntActiP52037. 3 interactions.
MINTiMINT-1242731.
STRINGi511145.b2902.

Structurei

3D structure databases

ProteinModelPortaliP52037.
SMRiP52037. Positions 3-247.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CYX. Bacteria.
ENOG410XNUN. LUCA.
InParanoidiP52037.
OMAiVEWRENA.
OrthoDBiEOG6N3CR8.
PhylomeDBiP52037.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52037-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIALVTGGS RGIGRATALL LAQEGYTVAV NYQQNLHAAQ EVMNLITQAG
60 70 80 90 100
GKAFVLQADI SDENQVVAMF TAIDQHDEPL AALVNNAGIL FTQCTVENLT
110 120 130 140 150
AERINRVLST NVTGYFLCCR EAVKRMALKN GGSGGAIVNV SSVASRLGSP
160 170 180 190 200
GEYVDYAASK GAIDTLTTGL SLEVAAQGIR VNCVRPGFIY TEMHASGGEP
210 220 230 240
GRVDRVKSNI PMQRGGQAEE VAQAIVWLLS DKASYVTGSF IDLAGGK
Length:247
Mass (Da):25,938
Last modified:November 1, 1997 - v2
Checksum:i8F17257B5905E4F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69070.1.
U28375 Genomic DNA. Translation: AAA83083.1.
U00096 Genomic DNA. Translation: AAC75940.1.
AP009048 Genomic DNA. Translation: BAE76967.1.
D21144 Genomic DNA. Translation: BAA04680.1.
U83189 Genomic DNA. Translation: AAB40290.1.
PIRiF65074.
RefSeqiNP_417378.1. NC_000913.3.
WP_000951964.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75940; AAC75940; b2902.
BAE76967; BAE76967; BAE76967.
GeneIDi947373.
KEGGiecj:JW2870.
eco:b2902.
PATRICi32121218. VBIEscCol129921_2997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69070.1.
U28375 Genomic DNA. Translation: AAA83083.1.
U00096 Genomic DNA. Translation: AAC75940.1.
AP009048 Genomic DNA. Translation: BAE76967.1.
D21144 Genomic DNA. Translation: BAA04680.1.
U83189 Genomic DNA. Translation: AAB40290.1.
PIRiF65074.
RefSeqiNP_417378.1. NC_000913.3.
WP_000951964.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP52037.
SMRiP52037. Positions 3-247.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260859. 2 interactions.
DIPiDIP-12165N.
IntActiP52037. 3 interactions.
MINTiMINT-1242731.
STRINGi511145.b2902.

Proteomic databases

EPDiP52037.
PaxDbiP52037.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75940; AAC75940; b2902.
BAE76967; BAE76967; BAE76967.
GeneIDi947373.
KEGGiecj:JW2870.
eco:b2902.
PATRICi32121218. VBIEscCol129921_2997.

Organism-specific databases

EchoBASEiEB2798.
EcoGeneiEG12971. ygfF.

Phylogenomic databases

eggNOGiENOG4105CYX. Bacteria.
ENOG410XNUN. LUCA.
InParanoidiP52037.
OMAiVEWRENA.
OrthoDBiEOG6N3CR8.
PhylomeDBiP52037.

Enzyme and pathway databases

BioCyciEcoCyc:G7514-MONOMER.
ECOL316407:JW2870-MONOMER.
RETL1328306-WGS:GSTH-3971-MONOMER.

Miscellaneous databases

PROiP52037.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Analysis of products of the Escherichia coli genomic genes and regulation of their expressions: an applicable procedure for genomic analysis of other microorganisms."
    Talukder A.A., Yanai S., Yamada M.
    Biosci. Biotechnol. Biochem. 58:117-120(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-74.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 137-197.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYGFF_ECOLI
AccessioniPrimary (citable) accession number: P52037
Secondary accession number(s): P77138, Q2M9T9, Q46830
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.