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P52031

- G6PI_DROYA

UniProt

P52031 - G6PI_DROYA

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Protein
Glucose-6-phosphate isomerase
Gene
Pgi, GE22729
Organism
Drosophila yakuba (Fruit fly)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei362 – 3621Proton donor By similarity
Active sitei393 – 3931 By similarity
Active sitei523 – 5231 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
  2. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:Pgi
ORF Names:GE22729
OrganismiDrosophila yakuba (Fruit fly)
Taxonomic identifieri7245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000002282: Chromosome 2L, UP000002282: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0013171. Dyak\Pgi.

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 558558Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180545Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7245.FBpp0267739.

Structurei

3D structure databases

ProteinModelPortaliP52031.
SMRiP52031. Positions 8-554.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OrthoDBiEOG7FXZXV.
PhylomeDBiP52031.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52031-1 [UniParc]FASTAAdd to Basket

« Hide

MAGPLPPLNQ EAAFQKLQEY YDSSGKDLNI KDLFVKDAKR FSKYSLRLHT    50
QNDGEILLDY SKNRINDEVW DLLLALAKVR RVDAARDAMF SGQHINITEN 100
RAVLHTALRN RGTDPVLVDD KDVMPDVRAE LAHMKEFTNM VISGVWRGCT 150
GKQITDVVNI GIGGSDLGPL MVTEALKPYG KGLHSHFVSN IDGTHLAEVL 200
KKVNYETTLF IVASKTFTTQ ETITNATSAK TWLLEHSKEP ESVAKHFVAL 250
STNKEKVTEF GIDSTNMFGF WDWVGGRYSL WSAIGLSICL SIGFENFEQL 300
LDGAHYMDNH FRTTPLEKNA PVILALLGVW YSNFFKAETH ALLPYDQYLH 350
RFAAYFQQGD MESNGKFVSK AGKAVKYSTG PIVWGEPGTN GQHAFYQLIH 400
QGTRLIPCDF IAPAQTHNPI AGGKHHKILL SNFLAQTEAL MAGKTVDEAR 450
AELSKAGLCG NELDNLLPHK VFVGNRPTNS IVVKKVSPFT LGALIALYEH 500
KIFVQGIIWD INSFDQWGVE LGKQLAKAIE PELDHCNEVS THDSSTNGLI 550
NFIKANWK 558
Length:558
Mass (Da):62,191
Last modified:October 1, 1996 - v1
Checksum:iBB73495CE60D3356
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27673 Genomic DNA. Translation: AAA28787.1.
L27674 Genomic DNA. Translation: AAA28788.1.
L27675 Genomic DNA. Translation: AAB59188.1.
L27676 Genomic DNA. Translation: AAA28806.1.
L27677 Genomic DNA. Translation: AAA28807.1.
L27678 Genomic DNA. Translation: AAA28808.1.
L27679 Genomic DNA. Translation: AAA28809.1.
L27680 Genomic DNA. Translation: AAA28810.1.
L27681 Genomic DNA. Translation: AAA28811.1.
L27682 Genomic DNA. Translation: AAA28812.1.
L27683 Genomic DNA. Translation: AAA28813.1.
L27684 Genomic DNA. Translation: AAA28814.1.
L27685 Genomic DNA. Translation: AAA28815.1.
CM000157 Genomic DNA. Translation: EDW89413.1.
RefSeqiXP_002089701.1. XM_002089665.1.

Genome annotation databases

EnsemblMetazoaiFBtr0269247; FBpp0267739; FBgn0013171.
GeneIDi6528659.
KEGGidya:Dyak_GE22729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27673 Genomic DNA. Translation: AAA28787.1 .
L27674 Genomic DNA. Translation: AAA28788.1 .
L27675 Genomic DNA. Translation: AAB59188.1 .
L27676 Genomic DNA. Translation: AAA28806.1 .
L27677 Genomic DNA. Translation: AAA28807.1 .
L27678 Genomic DNA. Translation: AAA28808.1 .
L27679 Genomic DNA. Translation: AAA28809.1 .
L27680 Genomic DNA. Translation: AAA28810.1 .
L27681 Genomic DNA. Translation: AAA28811.1 .
L27682 Genomic DNA. Translation: AAA28812.1 .
L27683 Genomic DNA. Translation: AAA28813.1 .
L27684 Genomic DNA. Translation: AAA28814.1 .
L27685 Genomic DNA. Translation: AAA28815.1 .
CM000157 Genomic DNA. Translation: EDW89413.1 .
RefSeqi XP_002089701.1. XM_002089665.1.

3D structure databases

ProteinModelPortali P52031.
SMRi P52031. Positions 8-554.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7245.FBpp0267739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0269247 ; FBpp0267739 ; FBgn0013171 .
GeneIDi 6528659.
KEGGi dya:Dyak_GE22729.

Organism-specific databases

FlyBasei FBgn0013171. Dyak\Pgi.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OrthoDBi EOG7FXZXV.
PhylomeDBi P52031.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. McDonald J.H., Kreitman M.E.
    Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Brazzaville.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tai18E2 / Tucson 14021-0261.01.

Entry informationi

Entry nameiG6PI_DROYA
AccessioniPrimary (citable) accession number: P52031
Secondary accession number(s): B4P3E0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi