Cytochrome c-type protein TorY - Escherichia coli (strain K12)

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P52005 (TORY_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 112. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Cytochrome c-type protein TorY

Gene names

Name:	torY
Synonyms:	yecK
Ordered Locus Names:	b1873, JW1862

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme.
Subcellular location	Cell inner membrane; Single-pass type II membrane protein By similarity.
Post-translational modification	Binds 5 heme groups per subunit By similarity.
Sequence similarities	Belongs to the TorC/TorY family.

Ontologies

Keywords
Biological process	Electron transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Gram-negative-bacterium-type cell wall Inferred from electronic annotation. Source: InterPro integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro trimethylamine-N-oxide reductase (cytochrome c) activity Inferred from direct assay Ref.6. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 366

366

Cytochrome c-type protein TorY

PRO_0000108429

Regions

Topological domain

1 – 6

Cytoplasmic Potential

Transmembrane

7 – 27

Helical; Potential

Topological domain

28 – 366

339

Periplasmic Potential

Sites

Metal binding

Iron (heme 1 axial ligand) By similarity

Metal binding

Iron (heme 2 axial ligand) By similarity

Metal binding

133

Iron (heme 3 axial ligand) By similarity

Metal binding

165

Iron (heme 4 axial ligand) By similarity

Metal binding

317

Iron (heme 5 axial ligand) By similarity

Binding site

Heme 1 (covalent) By similarity

Binding site

Heme 1 (covalent) By similarity

Binding site

Heme 2 (covalent) By similarity

Binding site

Heme 2 (covalent) By similarity

Binding site

129

Heme 3 (covalent) By similarity

Binding site

132

Heme 3 (covalent) By similarity

Binding site

161

Heme 4 (covalent) By similarity

Binding site

164

Heme 4 (covalent) By similarity

Binding site

313

Heme 5 (covalent) By similarity

Binding site

316

Heme 5 (covalent) By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

P52005 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 1ED252C9882D98E3
Show »

FASTA

366

40,286

        10         20         30         40         50         60 
MRGKKRIGLL FLLIAVVVGG GGLLLAQKVL HKTSDTAFCL SCHSMSKPFE EYQGTVHFSN 

        70         80         90        100        110        120 
QKGIRAECAD CHIPKSGMDY LFAKLKASKD IYHEFVSGKI DSDDKFEAHR QEMAETVWKE 

       130        140        150        160        170        180 
LKATDSATCR SCHSFDAMDI ASQSESAQKM HNKAQKDSET CIDCHKGIAH FPPEIKMDDN 

       190        200        210        220        230        240 
AAHELESQAA TSVTNGAHIY PFKTSHIGEL ATVNPGTDLT VVDASGKQPI VLLQGYQMQG 

       250        260        270        280        290        300 
SENTLYLAAG QRLALATLSE EGIKALTVNG EWQADEYGNQ WRQASLQGAL TDPALADRKP 

       310        320        330        340        350        360 
LWQYAEKLDD TYCAGCHAPI AADHYTVNAW PSIAKGMGAR TSMSENELDI LTRYFQYNAK 


DITEKQ

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. Horiuchi T. DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Alternative gene for biotin sulfoxide reduction in Escherichia coli K-12." del Campillo-Campbell A., Campbell A.M. J. Mol. Evol. 42:85-90(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 292-366. Strain: K12 / ACC5.
[5]	Rudd K.E. Unpublished observations (MAR-1996) Cited for: IDENTIFICATION.
[6]	"The torYZ (yecK bisZ) operon encodes a third respiratory trimethylamine N-oxide reductase in Escherichia coli." Gon S., Patte J.-C., Mejean V., Iobbi-Nivol C. J. Bacteriol. 182:5779-5786(2000) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERIZATION. Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74943.1. AP009048 Genomic DNA. Translation: BAA15683.1. U38839 Genomic DNA. No translation available.
PIR	A64950.
RefSeq	NP_416387.1. NC_000913.2. YP_490135.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P52005.
SMR	P52005. Positions 12-174, 307-363.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-11829N.
IntAct	P52005. 1 interaction.
STRING	511145.b1873.
Protein family/group databases
TCDB	5.A.3.4.2. prokaryotic molybdopterin-containing oxidoreductase (PMO) family.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74943; AAC74943; b1873. BAA15683; BAA15683; BAA15683.
GeneID	12931356. 946490.
KEGG	ecj:Y75_p1849. eco:b1873.
PATRIC	32119071. VBIEscCol129921_1953.
Organism-specific databases
EchoBASE	EB3062.
EcoGene	EG13277. torY.
Phylogenomic databases
eggNOG	COG3005.
HOGENOM	HOG000284378.
KO	K07821.
OMA	FNANQWI.
ProtClustDB	CLSK874610.
Enzyme and pathway databases
BioCyc	EcoCyc:G7023-MONOMER. ECOL316407:JW1862-MONOMER. MetaCyc:G7023-MONOMER.
Gene expression databases
Genevestigator	P52005.
Family and domain databases
InterPro	IPR009154. Membr-bd_4haem_cyt_TorC. IPR011031. Multihaem_cyt. IPR005126. NapC/NirT_cyt_c_N. [Graphical view]
Pfam	PF03264. Cytochrom_NNT. 1 hit. [Graphical view]
PIRSF	PIRSF000014. 4_hem_cytch_TorC. 1 hit.
PROSITE	PS51008. MULTIHEME_CYTC. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TORY_ECOLI

Accession

Primary (citable) accession number: P52005
Secondary accession number(s): P76293

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 112 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents