Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P51903 (PGK_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 417416Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145841

Regions

Nucleotide binding373 – 3764ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1231Substrate By similarity
Binding site1711Substrate By similarity
Binding site2201ATP By similarity
Binding site3131ATP; via carbonyl oxygen By similarity
Binding site3441ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P51903 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: D4C3BEC9D40D5FDA

FASTA41744,717
        10         20         30         40         50         60 
MSLSNKLTLD KVDVKGKRVV MRVDFNVPMK DHKITNNQRI KAAVPTIKHC LDHGAKSVVL 

        70         80         90        100        110        120 
MSHLGRPDGV PMPDKFSFSP VAVELKALLG REVSFLKDCV GPEVEKACAN PANGSVILLE 

       130        140        150        160        170        180 
NLRFHVEEEG KGKDASGNKI KADAAKVEAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVH 

       190        200        210        220        230        240 
LPQKAAGFLM KKELDYFAKA LESPERPFLA ILGGAKVQDK IQLISNMLDK VNEMIIGGGM 

       250        260        270        280        290        300 
AFTFLKVLNN MQIGNSLFDE EGSKIVKDLM AKAEKNGVKI TLPVDFITAD KFDEHAQTGE 

       310        320        330        340        350        360 
ATVASGIPAG WMGLDCGPES VKKFVEVVGR AKQIVWNGPV GVFEWDKFSK GTKALMDKVV 

       370        380        390        400        410 
EVTGKGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSSV 

« Hide

References

[1]"Localization of the chicken PgK gene to chromosome 4p by fluorescence in situ hybridization."
Rauen K.A., le Ciel C.D., Abbott U.K., Hutchison N.J.
J. Hered. 85:147-150(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Skeletal muscle.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L37101 mRNA. Translation: AAC42219.1.
PIRI50407.
RefSeqNP_990316.1. NM_204985.2.
UniGeneGga.8606.

3D structure databases

ProteinModelPortalP51903.
SMRP51903. Positions 2-417.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid676107. 2 interactions.
IntActP51903. 1 interaction.
STRING9031.ENSGALP00000012878.

Proteomic databases

PaxDbP51903.
PRIDEP51903.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID395833.
KEGGgga:395833.

Organism-specific databases

CTD5230.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
HOVERGENHBG008177.
InParanoidP51903.
KOK00927.
PhylomeDBP51903.

Enzyme and pathway databases

ReactomeREACT_115655. Metabolism.
SABIO-RKP51903.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20815901.
PROP51903.

Entry information

Entry namePGK_CHICK
AccessionPrimary (citable) accession number: P51903
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways