##gff-version 3
P51817	UniProtKB	Chain	1	358	.	.	.	ID=PRO_0000086582;Note=CAMP-dependent protein kinase catalytic subunit PRKX	
P51817	UniProtKB	Domain	49	303	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P51817	UniProtKB	Domain	304	358	.	.	.	Note=AGC-kinase C-terminal;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00618	
P51817	UniProtKB	Region	1	34	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P51817	UniProtKB	Active site	172	172	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
P51817	UniProtKB	Binding site	55	63	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P51817	UniProtKB	Binding site	78	78	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P51817	UniProtKB	Modified residue	1	1	.	.	.	Note=N-acetylmethionine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378	
P51817	UniProtKB	Modified residue	203	203	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q922R0	
P51817	UniProtKB	Natural variant	43	43	.	.	.	ID=VAR_061744;Note=V->A;Dbxref=dbSNP:rs3752362	
P51817	UniProtKB	Mutagenesis	78	78	.	.	.	Note=Loss of function. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12082174;Dbxref=PMID:12082174	
P51817	UniProtKB	Mutagenesis	93	93	.	.	.	Note=Constitutive kinase activity%3B when associated with R-202. H->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16236808;Dbxref=PMID:16236808	
P51817	UniProtKB	Mutagenesis	202	202	.	.	.	Note=Constitutive kinase activity%3B when associated with Q-93. W->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16236808;Dbxref=PMID:16236808	
P51817	UniProtKB	Mutagenesis	283	283	.	.	.	Note=Increases the affinity for PRKAR2A and PRKAR2B. R->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20819953;Dbxref=PMID:20819953