P51809 (VAMP7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Vesicle-associated membrane protein 7
Short name=VAMP-7

Alternative name(s):
Synaptobrevin-like protein 1
Tetanus-insensitive VAMP
Short name=Ti-VAMP

Gene names

Name:	VAMP7
Synonyms:	SYBL1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. Ref.9 Ref.10 Ref.12
Subunit structure	Component of the SNARE complex composed of STX4, SNAP23 and VAMP7 that binds SYT7 during lysosomal exocytosis. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is required for heterotypic fusion of late endosomes with lysosomes in liver cells By similarity.
Subcellular location	Cytoplasmic vesicle › secretory vesicle membrane; Single-pass type IV membrane protein By similarity. Golgi apparatus › trans-Golgi network membrane; Single-pass type IV membrane protein By similarity. Late endosome membrane; Single-pass type IV membrane protein By similarity. Lysosome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein By similarity. Cytoplasmic vesicle › phagosome membrane; Single-pass type IV membrane protein By similarity. Cell junction › synapse › synaptosome By similarity. Note: In immature neurons expression is localized in vesicular structures in axons and dendrites while in mature neurons it is localized to the somatodendritic region. Colocalizes with LAMP1 in kidney cells. Localization to the endoplasmic reticulum membrane was observed in the intestine but not in liver or kidney By similarity. Ref.11
Tissue specificity	Detected in all tissues tested.
Miscellaneous	The gene encoding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Y chromosomes. Loss-of-function mutant (antisense inhibition) displays impaired granzyme B release and target cell killing by natural killer cells.
Sequence similarities	Belongs to the synaptobrevin family. Contains 1 longin domain. Contains 1 v-SNARE coiled-coil homology domain.
Sequence caution	The sequence BI547528 differs from that shown. Reason: Sequence of unknown origin in the C-terminal part.

Ontologies

Keywords
Biological process	Exocytosis Protein transport Transport
Cellular component	Cell junction Cytoplasmic vesicle Endoplasmic reticulum Endosome Golgi apparatus Lysosome Membrane Synapse Synaptosome
Coding sequence diversity	Alternative splicing
Domain	Coiled coil Signal-anchor Transmembrane Transmembrane helix
PTM	Acetylation
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	ER to Golgi vesicle-mediated transport Inferred from sequence or structural similarity PubMed 16495485. Source: UniProtKB Golgi to plasma membrane protein transport Inferred from electronic annotation. Source: Compara calcium ion-dependent exocytosis Inferred from sequence or structural similarity PubMed 14993220. Source: UniProtKB endosome to lysosome transport Inferred from direct assay Ref.9. Source: UniProtKB eosinophil degranulation Inferred from sequence or structural similarity PubMed 14993220. Source: UniProtKB neutrophil degranulation Inferred from sequence or structural similarity PubMed 14993220. Source: UniProtKB phagocytosis, engulfment Inferred from sequence or structural similarity PubMed 15133481. Source: UniProtKB post-Golgi vesicle-mediated transport Traceable author statement. Source: Reactome regulation of protein targeting to vacuolar membrane Inferred from electronic annotation. Source: Compara triglyceride transport Inferred from electronic annotation. Source: Compara vesicle fusion Inferred from direct assay Ref.9. Source: UniProtKB vesicle fusion with Golgi apparatus Inferred from electronic annotation. Source: Compara
Cellular_component	Golgi apparatus Inferred from direct assay. Source: HPA SNARE complex Inferred from sequence or structural similarity PubMed 15133481. Source: UniProtKB apical part of cell Inferred from electronic annotation. Source: Compara cell junction Inferred from electronic annotation. Source: UniProtKB-KW endoplasmic reticulum membrane Inferred from sequence or structural similarity PubMed 16495485. Source: UniProtKB integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW late endosome membrane Inferred from sequence or structural similarity PubMed 10459012. Source: UniProtKB lysosomal membrane Inferred from sequence or structural similarity PubMed 10459012. Source: UniProtKB neuron projection Inferred from sequence or structural similarity. Source: UniProtKB perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara phagocytic vesicle Inferred from sequence or structural similarity PubMed 15470500. Source: UniProtKB phagocytic vesicle membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Traceable author statement. Source: Reactome synapse Inferred from electronic annotation. Source: UniProtKB-KW transport vesicle membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
AGFG1	P52594	7	EBI-1052205,EBI-996560

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: P51809-1)

Also known as: Ti-VAMPa/VAMP7a;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: P51809-2)

Also known as: Ti-VAMPb/VAMP7b;

The sequence of this isoform differs from the canonical sequence as follows:
     145-220: DLVAQRGERL...GFTWPSCVKK → VCHLQNYQQK...IFVLSTSLFL

Isoform 3 (identifier: P51809-3)

Also known as: Ti-VAMPc/VAMP7c;

The sequence of this isoform differs from the canonical sequence as follows:
     28-68: Missing.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

1

1

Removed Ref.8

Chain

2 – 220

219

Vesicle-associated membrane protein 7

PRO_0000206761

Regions

Topological domain

2 – 188

187

Cytoplasmic Potential

Transmembrane

189 – 209

21

Helical; Anchor for type IV membrane protein; Potential

Topological domain

210 – 220

11

Vesicular Potential

Domain

7 – 110

104

Longin

Domain

125 – 185

61

v-SNARE coiled-coil homology

Amino acid modifications

Modified residue

2

1

N-acetylalanine; partial Ref.8

Natural variations

Alternative sequence

28 – 68

41

Missing in isoform 3.

VSP_017508

Alternative sequence

145 – 220

76

DLVAQ…SCVKK → VCHLQNYQQKSCSSHVYEEP QAHYYHHHRINCVHLYHCFT SLWWIYMAKLCEEIGKKKLP LTKDMREQGVKSNPCDSSLS HTDRWYLPVSSTLFSLFKIL FHASRFIFVLSTSLFL in isoform 2.

VSP_017509

Experimental info

Sequence conflict

98

1

L → P in BAD96514. Ref.5

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

220

Helix Strand Turn

Details...

Beta strand

5 – 10

6

Beta strand

13 – 19

7

Beta strand

21 – 23

3

Helix

26 – 33

8

Beta strand

38 – 40

3

Beta strand

42 – 47

6

Beta strand

50 – 57

8

Beta strand

60 – 70

11

Helix

72 – 89

18

Helix

91 – 95

5

Helix

103 – 117

15

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (Ti-VAMPa/VAMP7a) [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 9C1AA5C590375CEF	FASTA	220	24,935
	10 20 30 40 50 60 MAILFAVVAR GTTILAKHAW CGGNFLEVTE QILAKIPSEN NKLTYSHGNY LFHYICQDRI 70 80 90 100 110 120 VYLCITDDDF ERSRAFNFLN EIKKRFQTTY GSRAQTALPY AMNSEFSSVL AAQLKHHSEN 130 140 150 160 170 180 KGLDKVMETQ AQVDELKGIM VRNIDLVAQR GERLELLIDK TENLVDSSVT FKTTSRNLAR 190 200 210 220 AMCMKNLKLT IIIIIVSIVF IYIIVSPLCG GFTWPSCVKK
	Isoform 2 (Ti-VAMPb/VAMP7b) [UniParc]. Checksum: AB6942EF4ACD2978	FASTA	260	30,217
	10 20 30 40 50 60 MAILFAVVAR GTTILAKHAW CGGNFLEVTE QILAKIPSEN NKLTYSHGNY LFHYICQDRI 70 80 90 100 110 120 VYLCITDDDF ERSRAFNFLN EIKKRFQTTY GSRAQTALPY AMNSEFSSVL AAQLKHHSEN 130 140 150 160 170 180 KGLDKVMETQ AQVDELKGIM VRNIVCHLQN YQQKSCSSHV YEEPQAHYYH HHRINCVHLY 190 200 210 220 230 240 HCFTSLWWIY MAKLCEEIGK KKLPLTKDMR EQGVKSNPCD SSLSHTDRWY LPVSSTLFSL 250 260 FKILFHASRF IFVLSTSLFL
	Isoform 3 (Ti-VAMPc/VAMP7c) [UniParc]. Checksum: FE272984659C2B96	FASTA	179	20,121
	10 20 30 40 50 60 MAILFAVVAR GTTILAKHAW CGGNFLEDFE RSRAFNFLNE IKKRFQTTYG SRAQTALPYA 70 80 90 100 110 120 MNSEFSSVLA AQLKHHSENK GLDKVMETQA QVDELKGIMV RNIDLVAQRG ERLELLIDKT 130 140 150 160 170 ENLVDSSVTF KTTSRNLARA MCMKNLKLTI IIIIVSIVFI YIIVSPLCGG FTWPSCVKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation." D'Esposito M., Ciccodicola A., Gianfrancesco F., Esposito T., Flagiello L., Mazzarella R., Schlessinger D., D'Urso M. Nat. Genet. 13:227-229(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]	"Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region." Ciccodicola A., D'Esposito M., Esposito T., Gianfrancesco F., Migliaccio C., Miano M.G., Matarazzo M.R., Vacca M., Franze A., Cuccurese M., Cocchia M., Curci A., Terracciano A., Torino A., Cocchia S., Mercadante G., Pannone E., Archidiacono N. , Rocchi M., Schlessinger D., D'Urso M. Hum. Mol. Genet. 9:395-401(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"A dual mechanism controlling the localization and function of exocytic v-SNARE." Martinez-Arca S., Rudge R., Vacca M., Camonis J., Daviet L., Formstecher E., Hamburger A., Filippini F., D'Esposito M., Galli T. Proc. Natl. Acad. Sci. U.S.A. 100:9011-9016(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3). Tissue: Brain.
[4]	"Alternative splicing of SYBL1 gene." D'Esposito M., Filippini F., Rossi V., D'Urso M. Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
[5]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Liver.
[6]	"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R. Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Hippocampus and Uterus.
[8]	Bienvenut W.V. Submitted (JUN-2005) to UniProtKB Cited for: PROTEIN SEQUENCE OF 2-10; 126-137 AND 143-150, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, MASS SPECTROMETRY. Tissue: B-cell lymphoma.
[9]	"Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages." Ward D.M., Pevsner J., Scullion M.A., Vaughn M., Kaplan J. Mol. Biol. Cell 11:2327-2333(2000) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[10]	"A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils." Logan M.R., Lacy P., Odemuyiwa S.O., Steward M., Davoine F., Kita H., Moqbel R. Allergy 61:777-784(2006) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[11]	"Integral and associated lysosomal membrane proteins." Schroeder B., Wrocklage C., Pan C., Jaeger R., Koesters B., Schaefer H., Elsaesser H.-P., Mann M., Hasilik A. Traffic 8:1676-1686(2007) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Tissue: Placenta.
[12]	"Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line." Marcet-Palacios M., Odemuyiwa S.O., Coughlin J.J., Garofoli D., Ewen C., Davidson C.E., Ghaffari M., Kane K.P., Lacy P., Logan M.R., Befus A.D., Bleackley R.C., Moqbel R. Biochem. Biophys. Res. Commun. 366:617-623(2008) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[13]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]	"Solution structure of the longin domain of synaptobrevin-like protein 1." RIKEN structural genomics initiative (RSGI) Submitted (OCT-2006) to the PDB data bank Cited for: STRUCTURE BY NMR OF 1-118.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X92396 mRNA. Translation: CAA63133.1.
AJ271736 Genomic DNA. Translation: CAB96816.1.
AJ549301 mRNA. Translation: CAD70593.2.
AJ295938 mRNA. Translation: CAC16891.1.
AK222794 mRNA. Translation: BAD96514.1.
BC056141 mRNA. Translation: AAH56141.1.
BI547528 mRNA. No translation available.

IPI

IPI00013236.
IPI00020887.
IPI00401804.

RefSeq

NP_001138621.1. NM_001145149.2.
NP_001172112.1. NM_001185183.1.
NP_005629.1. NM_005638.5.

UniGene

Hs.24167.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2DMW	NMR	-	A	1-118	[»]
2VX8	X-ray	2.20	A/B/C/D	1-120	[»]

ProteinModelPortal

P51809.

ModBase

Search...

Protein-protein interaction databases

IntAct

P51809. 3 interactions.

STRING

9606.ENSP00000286448.

PTM databases

PhosphoSite

P51809.

Polymorphism databases

DMDM

1723133.

Proteomic databases

PaxDb

P51809.

PRIDE

P51809.

Protocols and materials databases

DNASU

6845.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000262640; ENSP00000262640; ENSG00000124333.
ENST00000286448; ENSP00000286448; ENSG00000124333.
ENST00000460621; ENSP00000427822; ENSG00000124333.

GeneID

6845.

KEGG

hsa:6845.

UCSC

uc004fnr.3. human.
uc004fns.3. human.
uc004fnt.3. human.

Organism-specific databases

CTD

6845.

GeneCards

GC0XP155110.

HGNC

HGNC:11486. VAMP7.

HPA

HPA036733.

MIM

300053. gene.

neXtProt

NX_P51809.

PharmGKB

PA162408786.

GenAtlas

Search...

Phylogenomic databases

eggNOG

COG5143.

HOGENOM

HOG000042711.

HOVERGEN

HBG006675.

KO

K08515.

OMA

CITDDEF.

OrthoDB

EOG49079V.

Enzyme and pathway databases

Reactome

REACT_11123. Membrane Trafficking.

Gene expression databases

ArrayExpress

P51809.

Bgee

P51809.

CleanEx

HS_VAMP7.

Genevestigator

P51809.

GermOnline

ENSG00000124333. Homo sapiens.

Family and domain databases

Gene3D

3.30.450.50. 1 hit.

InterPro

IPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]

Pfam

PF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]

PRINTS

PR00219. SYNAPTOBREVN.

SUPFAM

SSF64356. Longin_like. 1 hit.

PROSITE

PS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P51809.

GenomeRNAi

6845.

NextBio

26723.

SOURCE

Search...

Entry information

Entry name

VAMP7_HUMAN

Accession

Primary (citable) accession number: P51809
Secondary accession number(s): Q53GY7, Q7Z409, Q9H4A7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 129 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.