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P51805

- PLXA3_HUMAN

UniProt

P51805 - PLXA3_HUMAN

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Protein

Plexin-A3

Gene

PLXNA3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

GO - Molecular functioni

  1. semaphorin receptor activity Source: Ensembl
  2. transmembrane signaling receptor activity Source: UniProtKB

GO - Biological processi

  1. axon guidance Source: Reactome
  2. branchiomotor neuron axon guidance Source: Ensembl
  3. facial nerve structural organization Source: Ensembl
  4. hippocampus development Source: Ensembl
  5. multicellular organismal development Source: UniProtKB
  6. negative chemotaxis Source: Ensembl
  7. negative regulation of axon extension involved in axon guidance Source: Ensembl
  8. positive regulation of cytoskeleton organization Source: Ensembl
  9. pyramidal neuron development Source: Ensembl
  10. semaphorin-plexin signaling pathway Source: BHF-UCL
  11. semaphorin-plexin signaling pathway involved in axon guidance Source: Ensembl
  12. trigeminal nerve structural organization Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Enzyme and pathway databases

ReactomeiREACT_19199. CRMPs in Sema3A signaling.
REACT_19236. Sema3A PAK dependent Axon repulsion.
REACT_19279. SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion.

Names & Taxonomyi

Protein namesi
Recommended name:
Plexin-A3
Alternative name(s):
Plexin-4
Semaphorin receptor SEX
Gene namesi
Name:PLXNA3
Synonyms:PLXN4, SEX
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:9101. PLXNA3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini20 – 12201201ExtracellularSequence AnalysisAdd
BLAST
Transmembranei1221 – 124121HelicalSequence AnalysisAdd
BLAST
Topological domaini1242 – 1871630CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. intracellular Source: InterPro
  3. membrane Source: UniProtKB
  4. plasma membrane Source: Reactome
  5. semaphorin receptor complex Source: BHF-UCL
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33427.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 18711852Plexin-A3PRO_0000024670Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi59 – 591N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi77 ↔ 86PROSITE-ProRule annotation
Disulfide bondi112 ↔ 120PROSITE-ProRule annotation
Disulfide bondi266 ↔ 387PROSITE-ProRule annotation
Disulfide bondi282 ↔ 338PROSITE-ProRule annotation
Disulfide bondi356 ↔ 375PROSITE-ProRule annotation
Disulfide bondi491 ↔ 508PROSITE-ProRule annotation
Disulfide bondi497 ↔ 539PROSITE-ProRule annotation
Disulfide bondi500 ↔ 517PROSITE-ProRule annotation
Disulfide bondi511 ↔ 523PROSITE-ProRule annotation
Glycosylationi548 – 5481N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi574 ↔ 594PROSITE-ProRule annotation
Glycosylationi637 – 6371N-linked (GlcNAc...)Sequence Analysis
Glycosylationi738 – 7381N-linked (GlcNAc...)Sequence Analysis
Glycosylationi746 – 7461N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1009 – 10091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1036 – 10361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1073 – 10731N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1115 – 11151N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1162 – 11621N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP51805.
PaxDbiP51805.
PRIDEiP51805.

PTM databases

PhosphoSiteiP51805.

Expressioni

Gene expression databases

BgeeiP51805.
CleanExiHS_PLXNA3.
GenevestigatoriP51805.

Interactioni

Subunit structurei

Interacts with CBFA2T3/MTG16.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
CBFA2T3O750812EBI-7135904,EBI-1190217

Protein-protein interaction databases

BioGridi120717. 7 interactions.
DIPiDIP-57386N.
IntActiP51805. 6 interactions.
MINTiMINT-7556947.
STRINGi9606.ENSP00000358696.

Structurei

3D structure databases

ProteinModelPortaliP51805.
SMRiP51805. Positions 30-684, 1246-1869.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 488469SemaPROSITE-ProRule annotationAdd
BLAST
Domaini840 – 93394IPT/TIG 1Add
BLAST
Domaini935 – 102086IPT/TIG 2Add
BLAST
Domaini1023 – 1122100IPT/TIG 3Add
BLAST
Domaini1125 – 121187IPT/TIG 4Add
BLAST

Sequence similaritiesi

Belongs to the plexin family.Curated
Contains 4 IPT/TIG domains.Curated
Contains 1 Sema domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG254546.
HOGENOMiHOG000231377.
HOVERGENiHBG105711.
InParanoidiP51805.
KOiK06820.
OMAiNTEGMAS.
OrthoDBiEOG7Q8CM9.
PhylomeDBiP51805.
TreeFamiTF312962.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
2.60.40.10. 4 hits.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR016201. Plexin-like_fold.
IPR013548. Plexin_cytoplasmic_RasGAP_dom.
IPR002165. Plexin_repeat.
IPR008936. Rho_GTPase_activation_prot.
IPR001627. Semap_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF08337. Plexin_cytopl. 1 hit.
PF01437. PSI. 3 hits.
PF01403. Sema. 1 hit.
PF01833. TIG. 4 hits.
[Graphical view]
SMARTiSM00429. IPT. 4 hits.
SM00423. PSI. 3 hits.
SM00630. Sema. 1 hit.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
SSF48350. SSF48350. 2 hits.
SSF81296. SSF81296. 4 hits.
PROSITEiPS51004. SEMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P51805-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSVCLLLLL FLAVGGALGN RPFRAFVVTD TTLTHLAVHR VTGEVFVGAV
60 70 80 90 100
NRVFKLAPNL TELRAHVTGP VEDNARCYPP PSMRVCAHRL APVDNINKLL
110 120 130 140 150
LIDYAARRLV ACGSIWQGIC QFLRLDDLFK LGEPHHRKEH YLSGAQEPDS
160 170 180 190 200
MAGVIVEQGQ GPSKLFVGTA VDGKSEYFPT LSSRKLISDE DSADMFSLVY
210 220 230 240 250
QDEFVSSQIK IPSDTLSLYP AFDIYYIYGF VSASFVYFLT LQLDTQQTLL
260 270 280 290 300
DTAGEKFFTS KIVRMCAGDS EFYSYVEFPI GCSWRGVEYR LVQSAHLAKP
310 320 330 340 350
GLLLAQALGV PADEDVLFTI FSQGQKNRAS PPRQTILCLF TLSNINAHIR
360 370 380 390 400
RRIQSCYRGE GTLALPWLLN KELPCINTPM QINGNFCGLV LNQPLGGLHV
410 420 430 440 450
IEGLPLLADS TDGMASVAAY TYRQHSVVFI GTRSGSLKKV RVDGFQDAHL
460 470 480 490 500
YETVPVVDGS PILRDLLFSP DHRHIYLLSE KQVSQLPVET CEQYQSCAAC
510 520 530 540 550
LGSGDPHCGW CVLRHRCCRE GACLGASAPH GFAEELSKCV QVRVRPNNVS
560 570 580 590 600
VTSPGVQLTV TLHNVPDLSA GVSCAFEAAA ENEAVLLPSG ELLCPSPSLQ
610 620 630 640 650
ELRALTRGHG ATRTVRLQLL SKETGVRFAG ADFVFYNCSV LQSCMSCVGS
660 670 680 690 700
PYPCHWCKYR HTCTSRPHEC SFQEGRVHSP EGCPEILPSG DLLIPVGVMQ
710 720 730 740 750
PLTLRAKNLP QPQSGQKNYE CVVRVQGRQQ RVPAVRFNSS SVQCQNASYS
760 770 780 790 800
YEGDEHGDTE LDFSVVWDGD FPIDKPPSFR ALLYKCWAQR PSCGLCLKAD
810 820 830 840 850
PRFNCGWCIS EHRCQLRTHC PAPKTNWMHL SQKGTRCSHP RITQIHPLVG
860 870 880 890 900
PKEGGTRVTI VGDNLGLLSR EVGLRVAGVR CNSIPAEYIS AERIVCEMEE
910 920 930 940 950
SLVPSPPPGP VELCVGDCSA DFRTQSEQVY SFVTPTFDQV SPSRGPASGG
960 970 980 990 1000
TRLTISGSSL DAGSRVTVTV RDSECQFVRR DAKAIVCISP LSTLGPSQAP
1010 1020 1030 1040 1050
ITLAIDRANI SSPGLIYTYT QDPTVTRLEP TWSIINGSTA ITVSGTHLLT
1060 1070 1080 1090 1100
VQEPRVRAKY RGIETTNTCQ VINDTAMLCK APGIFLGRPQ PRAQGEHPDE
1110 1120 1130 1140 1150
FGFLLDHVQT ARSLNRSSFT YYPDPSFEPL GPSGVLDVKP GSHVVLKGKN
1160 1170 1180 1190 1200
LIPAAAGSSR LNYTVLIGGQ PCSLTVSDTQ LLCDSPSQTG RQPVMVLVGG
1210 1220 1230 1240 1250
LEFWLGTLHI SAERALTLPA MMGLAAGGGL LLLAITAVLV AYKRKTQDAD
1260 1270 1280 1290 1300
RTLKRLQLQM DNLESRVALE CKEAFAELQT DINELTNHMD EVQIPFLDYR
1310 1320 1330 1340 1350
TYAVRVLFPG IEAHPVLKEL DTPPNVEKAL RLFGQLLHSR AFVLTFIHTL
1360 1370 1380 1390 1400
EAQSSFSMRD RGTVASLTMV ALQSRLDYAT GLLKQLLADL IEKNLESKNH
1410 1420 1430 1440 1450
PKLLLRRTES VAEKMLTNWF TFLLHKFLKE CAGEPLFLLY CAIKQQMEKG
1460 1470 1480 1490 1500
PIDAITGEAR YSLSEDKLIR QQIDYKTLTL HCVCPENEGS AQVPVKVLNC
1510 1520 1530 1540 1550
DSITQAKDKL LDTVYKGIPY SQRPKAEDMD LEWRQGRMTR IILQDEDVTT
1560 1570 1580 1590 1600
KIECDWKRLN SLAHYQVTDG SLVALVPKQV SAYNMANSFT FTRSLSRYES
1610 1620 1630 1640 1650
LLRTASSPDS LRSRAPMITP DQETGTKLWH LVKNHDHADH REGDRGSKMV
1660 1670 1680 1690 1700
SEIYLTRLLA TKGTLQKFVD DLFETVFSTA HRGSALPLAI KYMFDFLDEQ
1710 1720 1730 1740 1750
ADQRQISDPD VRHTWKSNCL PLRFWVNVIK NPQFVFDIHK NSITDACLSV
1760 1770 1780 1790 1800
VAQTFMDSCS TSEHRLGKDS PSNKLLYAKD IPNYKSWVER YYRDIAKMAS
1810 1820 1830 1840 1850
ISDQDMDAYL VEQSRLHASD FSVLSALNEL YFYVTKYRQE ILTALDRDAS
1860 1870
CRKHKLRQKL EQIISLVSSD S
Length:1,871
Mass (Da):207,703
Last modified:November 28, 2006 - v2
Checksum:iF0D21C3FD4CE9FBA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti222 – 2221F → L in CAA61132. (PubMed:8570614)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti384 – 3841G → S.
Corresponds to variant rs34585333 [ dbSNP | Ensembl ].
VAR_050595
Natural varianti413 – 4131G → S.
Corresponds to variant rs36115591 [ dbSNP | Ensembl ].
VAR_050596
Natural varianti863 – 8631D → E.1 Publication
Corresponds to variant rs5945430 [ dbSNP | Ensembl ].
VAR_050597

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87852 mRNA. Translation: CAA61132.1.
BX936365 Genomic DNA. Translation: CAI43194.1.
CCDSiCCDS14752.1.
RefSeqiNP_059984.3. NM_017514.4.
UniGeneiHs.632839.

Genome annotation databases

EnsembliENST00000369682; ENSP00000358696; ENSG00000130827.
GeneIDi55558.
KEGGihsa:55558.
UCSCiuc004flm.3. human.

Polymorphism databases

DMDMi118572690.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87852 mRNA. Translation: CAA61132.1 .
BX936365 Genomic DNA. Translation: CAI43194.1 .
CCDSi CCDS14752.1.
RefSeqi NP_059984.3. NM_017514.4.
UniGenei Hs.632839.

3D structure databases

ProteinModelPortali P51805.
SMRi P51805. Positions 30-684, 1246-1869.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120717. 7 interactions.
DIPi DIP-57386N.
IntActi P51805. 6 interactions.
MINTi MINT-7556947.
STRINGi 9606.ENSP00000358696.

PTM databases

PhosphoSitei P51805.

Polymorphism databases

DMDMi 118572690.

Proteomic databases

MaxQBi P51805.
PaxDbi P51805.
PRIDEi P51805.

Protocols and materials databases

DNASUi 55558.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000369682 ; ENSP00000358696 ; ENSG00000130827 .
GeneIDi 55558.
KEGGi hsa:55558.
UCSCi uc004flm.3. human.

Organism-specific databases

CTDi 55558.
GeneCardsi GC0XP153686.
H-InvDB HIX0203329.
HGNCi HGNC:9101. PLXNA3.
MIMi 300022. gene.
neXtProti NX_P51805.
PharmGKBi PA33427.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG254546.
HOGENOMi HOG000231377.
HOVERGENi HBG105711.
InParanoidi P51805.
KOi K06820.
OMAi NTEGMAS.
OrthoDBi EOG7Q8CM9.
PhylomeDBi P51805.
TreeFami TF312962.

Enzyme and pathway databases

Reactomei REACT_19199. CRMPs in Sema3A signaling.
REACT_19236. Sema3A PAK dependent Axon repulsion.
REACT_19279. SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion.

Miscellaneous databases

GeneWikii PLXNA3.
GenomeRNAii 55558.
NextBioi 60030.
PROi P51805.
SOURCEi Search...

Gene expression databases

Bgeei P51805.
CleanExi HS_PLXNA3.
Genevestigatori P51805.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
2.60.40.10. 4 hits.
InterProi IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR016201. Plexin-like_fold.
IPR013548. Plexin_cytoplasmic_RasGAP_dom.
IPR002165. Plexin_repeat.
IPR008936. Rho_GTPase_activation_prot.
IPR001627. Semap_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF08337. Plexin_cytopl. 1 hit.
PF01437. PSI. 3 hits.
PF01403. Sema. 1 hit.
PF01833. TIG. 4 hits.
[Graphical view ]
SMARTi SM00429. IPT. 4 hits.
SM00423. PSI. 3 hits.
SM00630. Sema. 1 hit.
[Graphical view ]
SUPFAMi SSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
SSF48350. SSF48350. 2 hits.
SSF81296. SSF81296. 4 hits.
PROSITEi PS51004. SEMA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor."
    Maestrini E., Tamagnone L., Longati P., Cremona O., Gulisano M., Bione S., Tamanini F., Neel B.G., Toniolo D., Comoglio P.M.
    Proc. Natl. Acad. Sci. U.S.A. 93:674-678(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT GLU-863.
    Tissue: Embryo, Fetal brain and Skeletal muscle.
  2. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner."
    Fiedler S.E., Schillace R.V., Daniels C.J., Andrews S.F., Carr D.W.
    FEBS Lett. 584:873-877(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CBFA2T3/MTG16.

Entry informationi

Entry nameiPLXA3_HUMAN
AccessioniPrimary (citable) accession number: P51805
Secondary accession number(s): Q5HY36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 28, 2006
Last modified: October 29, 2014
This is version 132 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3