P51778 (TAL_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Ava_0493

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 332	332	Transaldolase HAMAP MF_00492		PRO_0000173578
Sites
	Active site	136	1	By similarity
Experimental info
	Sequence conflict	204	1	D → Y in AAC41527. Ref.1
	Sequence conflict	309	1	T → S in AAC41527. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P51778 [UniParc]. Last modified April 4, 2006. Version 2. Checksum: 3536377CFEA0D692	FASTA	332	36,165
	10 20 30 40 50 60 MTKNLLEQLR EMTVVVADTG DIQAIEKFTP RDATTNPSLI TAAAKMPEYQ EIVDQTLLQA 70 80 90 100 110 120 KKDAGAGASK GQIVSLAFDR LAVSFGLKIL QIIPGRVSTE VDARLSYDTE ATITKARELI 130 140 150 160 170 180 AQYKAAGIGP ERVLIKIAST WEGIKAAEIL EKEGIHCNLT LLFGLHQAIA CAEAGITLIS 190 200 210 220 230 240 PFVGRILDWY KKETGRDSYP SAEDPGVISV TTIYNYYKKF GYTTEVMGAS FRNIGEITEL 250 260 270 280 290 300 AGSDLLTISP GLLGELQATI GELPRKLDPA KAATLDIEKI SIDKATFDKM HAADRMAYDK 310 320 330 LDEGIKGFTK ALEELETLLA ERLARLEVVA SH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Transaldolase genes from the cyanobacteria Anabaena variabilis and Synechocystis sp. PCC 6803: comparison with other eubacterial and eukaryotic homologues." Koehler U., Cerff R., Brinkmann H. Plant Mol. Biol. 30:213-218(1996) [PubMed: 8616240] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29413 / PCC 7937.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L47327 Genomic DNA. Translation: AAC41527.1. CP000117 Genomic DNA. Translation: ABA20117.1.
PIR	S72517.
RefSeq	YP_321012.1. NC_007413.1.
3D structure databases
ProteinModelPortal	P51778.
SMR	P51778. Positions 3-324.
ModBase	Search...
Protein-protein interaction databases
STRING	P51778.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3682400.
GenomeReviews	Gene locus Ava_0493 in contig CP000117_GR.
KEGG	ava:Ava_0493.
NMPDR	fig|240292.3.peg.1851.
PATRIC	35421342. VBIAnaVar43351_1243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HBG286747.
OMA	DWHKAKT.
PhylomeDB	P51778.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_0493-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_ANAVT

Accession

Primary (citable) accession number: P51778
Secondary accession number(s): Q3MFW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	April 4, 2006
Last modified:	January 25, 2012
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program