CCR8

Functionⁱ

Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.4 Publications

GO - Molecular functionⁱ

C-C chemokine receptor activity Source: Ensembl
chemokine receptor activity
Source: ProtInc
Traceable author statementⁱ
- 9417093
coreceptor activity
Source: ProtInc
Traceable author statementⁱ
- 9417093

Complete GO annotation...

GO - Biological processⁱ

cell adhesion
Source: ProtInc
Traceable author statementⁱ
- 10910894
chemotaxis
Source: ProtInc
Traceable author statementⁱ
- 10910894
G-protein coupled receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 8816377
immune response
Source: ProtInc
Traceable author statementⁱ
- 9670926
positive regulation of cytosolic calcium ion concentration
Source: ProtInc
Traceable author statementⁱ
- 9417093

Complete GO annotation...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380108. Chemokine receptors bind chemokines. R-HSA-418594. G alpha (i) signalling events.
SIGNORⁱ	P51685.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: C-C chemokine receptor type 8 Short name: C-C CKR-8 Short name: CC-CKR-8 Short name: CCR-8 Alternative name(s): CC chemokine receptor CHEMR1 CMKBRL2 Chemokine receptor-like 1 Short name: CKR-L1 GPR-CY6 Short name: GPRCY6 TER1 CD_antigen: CDw198
Gene namesⁱ	Name:CCR8 Synonyms:CKRL1, CMKBR8, CMKBRL2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1609. CCR8.

HGNCⁱ

HGNC:1609. CCR8.

Subcellular locationⁱ

Cell membrane; Multi-pass membrane protein

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 35	ExtracellularSequence analysisAdd BLAST	35
Transmembraneⁱ	36 – 63	Helical; Name=1Sequence analysisAdd BLAST	28
Topological domainⁱ	64 – 73	CytoplasmicSequence analysis	10
Transmembraneⁱ	74 – 93	Helical; Name=2Sequence analysisAdd BLAST	20
Topological domainⁱ	94 – 107	ExtracellularSequence analysisAdd BLAST	14
Transmembraneⁱ	108 – 129	Helical; Name=3Sequence analysisAdd BLAST	22
Topological domainⁱ	130 – 146	CytoplasmicSequence analysisAdd BLAST	17
Transmembraneⁱ	147 – 171	Helical; Name=4Sequence analysisAdd BLAST	25
Topological domainⁱ	172 – 202	ExtracellularSequence analysisAdd BLAST	31
Transmembraneⁱ	203 – 222	Helical; Name=5Sequence analysisAdd BLAST	20
Topological domainⁱ	223 – 238	CytoplasmicSequence analysisAdd BLAST	16
Transmembraneⁱ	239 – 263	Helical; Name=6Sequence analysisAdd BLAST	25
Topological domainⁱ	264 – 280	ExtracellularSequence analysisAdd BLAST	17
Transmembraneⁱ	281 – 304	Helical; Name=7Sequence analysisAdd BLAST	24
Topological domainⁱ	305 – 355	CytoplasmicSequence analysisAdd BLAST	51

GO - Cellular componentⁱ

integral component of plasma membrane
Source: ProtInc
Traceable author statementⁱ
- 8816377
plasma membrane Source: Reactome

Complete GO annotation...

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	1237.
Open Targets More...OpenTargetsⁱ	ENSG00000179934.
PharmGKBⁱ	PA26173.

Chemistry databases

ChEMBLⁱ	CHEMBL4596.
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	65.

Polymorphism and mutation databases

BioMutaⁱ	CCR8.
DMDMⁱ	1707884.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069288	1 – 355	C-C chemokine receptor type 8Add BLAST		355

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Disulfide bondⁱ	106 ↔ 183	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bond

Proteomic databases

PaxDbⁱ	P51685.
PeptideAtlas More...PeptideAtlasⁱ	P51685.
PRIDEⁱ	P51685.

PTM databases

iPTMnetⁱ	P51685.
PhosphoSitePlusⁱ	P51685.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000179934.
CleanExⁱ	HS_CCR8.
ExpressionAtlasⁱ	P51685. baseline and differential.
Genevisibleⁱ	P51685. HS.

Interactionⁱ

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-5836N.
Molecular INTeraction database More...MINTⁱ	MINT-140630.
STRINGⁱ	9606.ENSP00000326432.

Chemistry databases

BindingDBⁱ

P51685.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P51685.
SMRⁱ	P51685.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IJ9D. Eukaryota. ENOG410YUBT. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118785.
HOGENOMⁱ	HOG000234122.
HOVERGENⁱ	HBG106917.
InParanoidⁱ	P51685.
KEGG Orthology (KO) More...KOⁱ	K04183.
OMAⁱ	MFFITLM.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HEN.
PhylomeDBⁱ	P51685.
TreeFamⁱ	TF330966.

Family and domain databases

InterProⁱ	View protein in InterPro IPR004068. Chemokine_CCR8. IPR000355. Chemokine_rcpt. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit.
PRINTSⁱ	PR00657. CCCHEMOKINER. PR01530. CHEMOKINER8. PR00237. GPCRRHODOPSN.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: P51685-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDYTLDLSVT TVTDYYYPDI FSSPCDAELI QTNGKLLLAV FYCLLFVFSL 
        60         70         80         90        100
LGNSLVILVL VVCKKLRSIT DVYLLNLALS DLLFVFSFPF QTYYLLDQWV 
       110        120        130        140        150
FGTVMCKVVS GFYYIGFYSS MFFITLMSVD RYLAVVHAVY ALKVRTIRMG 
       160        170        180        190        200
TTLCLAVWLT AIMATIPLLV FYQVASEDGV LQCYSFYNQQ TLKWKIFTNF 
       210        220        230        240        250
KMNILGLLIP FTIFMFCYIK ILHQLKRCQN HNKTKAIRLV LIVVIASLLF 
       260        270        280        290        300
WVPFNVVLFL TSLHSMHILD GCSISQQLTY ATHVTEIISF THCCVNPVIY 
       310        320        330        340        350
AFVGEKFKKH LSEIFQKSCS QIFNYLGRQM PRESCEKSSS CQQHSSRSSS 

VDYIL

Length:355

Mass (Da):40,844

Last modified:October 1, 1996 - v1

Checksum:ⁱBC14A153CF695361

GO

Isoform 2 (identifier: P51685-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-91: MDYTLDLSVT...LLFVFSFPFQ → MRNLFRQM

« Hide

        10         20         30         40         50
MRNLFRQMTY YLLDQWVFGT VMCKVVSGFY YIGFYSSMFF ITLMSVDRYL 
        60         70         80         90        100
AVVHAVYALK VRTIRMGTTL CLAVWLTAIM ATIPLLVFYQ VASEDGVLQC 
       110        120        130        140        150
YSFYNQQTLK WKIFTNFKMN ILGLLIPFTI FMFCYIKILH QLKRCQNHNK 
       160        170        180        190        200
TKAIRLVLIV VIASLLFWVP FNVVLFLTSL HSMHILDGCS ISQQLTYATH 
       210        220        230        240        250
VTEIISFTHC CVNPVIYAFV GEKFKKHLSE IFQKSCSQIF NYLGRQMPRE 
       260        270 
SCEKSSSCQQ HSSRSSSVDY IL

Note: No experimental confirmation available.

Show »

Length:272

Mass (Da):31,622

Checksum:ⁱ1A78F1429FE3A4A3

GO

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_049384	27	A → G1 PublicationCorresponds to variant dbSNP:rs2853699Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_056340	1 – 91	MDYTL…SFPFQ → MRNLFRQM in isoform 2. 1 PublicationAdd BLAST		91

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z79782 Genomic DNA. Translation: CAB02142.1. Y08456 Genomic DNA. Translation: CAA69712.1. U45983 Genomic DNA. Translation: AAB61962.1. AF005210 mRNA. Translation: AAB62547.1. U62556 Genomic DNA. Translation: AAB05542.1. D49919 mRNA. Translation: BAA23387.1. AY016370 Genomic DNA. Translation: AAK08628.1. AK314957 mRNA. Translation: BAG37461.1. AC104850 Genomic DNA. No translation available. CH471055 Genomic DNA. Translation: EAW64577.1. BC069067 mRNA. Translation: AAH69067.1. BC074743 mRNA. Translation: AAH74743.1. BC107152 mRNA. Translation: AAI07153.1. BC107159 mRNA. Translation: AAI07160.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS2684.1. [P51685-1]
PIRⁱ	JC5067.
NCBI Reference Sequences More...RefSeqⁱ	NP_005192.1. NM_005201.3. [P51685-1]
UniGeneⁱ	Hs.113222.

Genome annotation databases

Ensemblⁱ	ENST00000326306; ENSP00000326432; ENSG00000179934. [P51685-1]
GeneIDⁱ	1237.
KEGGⁱ	hsa:1237.
UCSC genome browser More...UCSCⁱ	uc010hhr.3. human. [P51685-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Web resourcesⁱ

Wikipedia

CC chemokine receptors entry

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z79782 Genomic DNA. Translation: CAB02142.1. Y08456 Genomic DNA. Translation: CAA69712.1. U45983 Genomic DNA. Translation: AAB61962.1. AF005210 mRNA. Translation: AAB62547.1. U62556 Genomic DNA. Translation: AAB05542.1. D49919 mRNA. Translation: BAA23387.1. AY016370 Genomic DNA. Translation: AAK08628.1. AK314957 mRNA. Translation: BAG37461.1. AC104850 Genomic DNA. No translation available. CH471055 Genomic DNA. Translation: EAW64577.1. BC069067 mRNA. Translation: AAH69067.1. BC074743 mRNA. Translation: AAH74743.1. BC107152 mRNA. Translation: AAI07153.1. BC107159 mRNA. Translation: AAI07160.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS2684.1. [P51685-1]
PIRⁱ	JC5067.
NCBI Reference Sequences More...RefSeqⁱ	NP_005192.1. NM_005201.3. [P51685-1]
UniGeneⁱ	Hs.113222.

3D structure databases

ProteinModelPortalⁱ	P51685.
SMRⁱ	P51685.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-5836N.
Molecular INTeraction database More...MINTⁱ	MINT-140630.
STRINGⁱ	9606.ENSP00000326432.

Chemistry databases

BindingDBⁱ	P51685.
ChEMBLⁱ	CHEMBL4596.
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	65.

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	P51685.
PhosphoSitePlusⁱ	P51685.

Polymorphism and mutation databases

BioMutaⁱ	CCR8.
DMDMⁱ	1707884.

Proteomic databases

PaxDbⁱ	P51685.
PeptideAtlas More...PeptideAtlasⁱ	P51685.
PRIDEⁱ	P51685.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	1237.
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000326306; ENSP00000326432; ENSG00000179934. [P51685-1]
GeneIDⁱ	1237.
KEGGⁱ	hsa:1237.
UCSC genome browser More...UCSCⁱ	uc010hhr.3. human. [P51685-1]

Organism-specific databases

CTDⁱ	1237.
DisGeNET More...DisGeNETⁱ	1237.
GeneCardsⁱ	CCR8.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1609. CCR8.
MIMⁱ	601834. gene.
neXtProtⁱ	NX_P51685.
Open Targets More...OpenTargetsⁱ	ENSG00000179934.
PharmGKBⁱ	PA26173.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IJ9D. Eukaryota. ENOG410YUBT. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118785.
HOGENOMⁱ	HOG000234122.
HOVERGENⁱ	HBG106917.
InParanoidⁱ	P51685.
KEGG Orthology (KO) More...KOⁱ	K04183.
OMAⁱ	MFFITLM.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HEN.
PhylomeDBⁱ	P51685.
TreeFamⁱ	TF330966.

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380108. Chemokine receptors bind chemokines. R-HSA-418594. G alpha (i) signalling events.
SIGNORⁱ	P51685.

Miscellaneous databases

GeneWikiⁱ	CCR8_(gene).
GenomeRNAiⁱ	1237.
Protein Ontology More...PROⁱ	PR:P51685.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000179934.
CleanExⁱ	HS_CCR8.
ExpressionAtlasⁱ	P51685. baseline and differential.
Genevisibleⁱ	P51685. HS.

Family and domain databases

InterProⁱ	View protein in InterPro IPR004068. Chemokine_CCR8. IPR000355. Chemokine_rcpt. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit.
PRINTSⁱ	PR00657. CCCHEMOKINER. PR01530. CHEMOKINER8. PR00237. GPCRRHODOPSN.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CCR8_HUMAN
Accessionⁱ	P51685Primary (citable) accession number: P51685 Secondary accession number(s): B2RC64 , Q3KNQ8, Q3KNR3, Q9BYX5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
	Last sequence update:	October 1, 1996
	Last modified:	June 7, 2017
	This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

Was originally thought to be a receptor for SCYA3 and SCYA17.1 Publication

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries
Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries
Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P51685 (CCR8_HUMAN)

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C-C chemokine receptor type 8

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequences (2)ⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ