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P51685

- CCR8_HUMAN

UniProt

P51685 - CCR8_HUMAN

Protein

C-C chemokine receptor type 8

Gene

CCR8

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 127 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.4 Publications

    GO - Molecular functioni

    1. C-C chemokine receptor activity Source: Ensembl
    2. chemokine receptor activity Source: ProtInc
    3. coreceptor activity Source: ProtInc

    GO - Biological processi

    1. cell adhesion Source: ProtInc
    2. chemokine-mediated signaling pathway Source: GOC
    3. chemotaxis Source: ProtInc
    4. G-protein coupled receptor signaling pathway Source: ProtInc
    5. immune response Source: ProtInc
    6. positive regulation of cytosolic calcium ion concentration Source: ProtInc

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_15344. Chemokine receptors bind chemokines.
    REACT_19231. G alpha (i) signalling events.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    C-C chemokine receptor type 8
    Short name:
    C-C CKR-8
    Short name:
    CC-CKR-8
    Short name:
    CCR-8
    Alternative name(s):
    CC chemokine receptor CHEMR1
    CMKBRL2
    Chemokine receptor-like 1
    Short name:
    CKR-L1
    GPR-CY6
    Short name:
    GPRCY6
    TER1
    CD_antigen: CDw198
    Gene namesi
    Name:CCR8
    Synonyms:CKRL1, CMKBR8, CMKBRL2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:1609. CCR8.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: ProtInc
    2. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA26173.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 355355C-C chemokine receptor type 8PRO_0000069288Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi106 ↔ 183PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PaxDbiP51685.
    PRIDEiP51685.

    PTM databases

    PhosphoSiteiP51685.

    Expressioni

    Gene expression databases

    ArrayExpressiP51685.
    BgeeiP51685.
    CleanExiHS_CCR8.
    GenevestigatoriP51685.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-5836N.
    MINTiMINT-140630.
    STRINGi9606.ENSP00000326432.

    Structurei

    3D structure databases

    ProteinModelPortaliP51685.
    SMRiP51685. Positions 15-316.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3535ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini64 – 7310CytoplasmicSequence Analysis
    Topological domaini94 – 10714ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini130 – 14617CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini172 – 20231ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini223 – 23816CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini264 – 28017ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini305 – 35551CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei36 – 6328Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei74 – 9320Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei108 – 12922Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei147 – 17125Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei203 – 22220Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei239 – 26325Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei281 – 30424Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG149415.
    HOGENOMiHOG000234122.
    HOVERGENiHBG106917.
    InParanoidiP51685.
    KOiK04183.
    OMAiLIYATHV.
    OrthoDBiEOG7B5WW3.
    PhylomeDBiP51685.
    TreeFamiTF330966.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR004068. Chemokine_CCR8.
    IPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PANTHERiPTHR24227. PTHR24227. 1 hit.
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00657. CCCHEMOKINER.
    PR01530. CHEMOKINER8.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P51685-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MDYTLDLSVT TVTDYYYPDI FSSPCDAELI QTNGKLLLAV FYCLLFVFSL    50
    LGNSLVILVL VVCKKLRSIT DVYLLNLALS DLLFVFSFPF QTYYLLDQWV 100
    FGTVMCKVVS GFYYIGFYSS MFFITLMSVD RYLAVVHAVY ALKVRTIRMG 150
    TTLCLAVWLT AIMATIPLLV FYQVASEDGV LQCYSFYNQQ TLKWKIFTNF 200
    KMNILGLLIP FTIFMFCYIK ILHQLKRCQN HNKTKAIRLV LIVVIASLLF 250
    WVPFNVVLFL TSLHSMHILD GCSISQQLTY ATHVTEIISF THCCVNPVIY 300
    AFVGEKFKKH LSEIFQKSCS QIFNYLGRQM PRESCEKSSS CQQHSSRSSS 350
    VDYIL 355
    Length:355
    Mass (Da):40,844
    Last modified:October 1, 1996 - v1
    Checksum:iBC14A153CF695361
    GO
    Isoform 2 (identifier: P51685-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-91: MDYTLDLSVT...LLFVFSFPFQ → MRNLFRQM

    Note: No experimental confirmation available.

    Show »
    Length:272
    Mass (Da):31,622
    Checksum:i1A78F1429FE3A4A3
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti27 – 271A → G.1 Publication
    Corresponds to variant rs2853699 [ dbSNP | Ensembl ].
    VAR_049384

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 9191MDYTL…SFPFQ → MRNLFRQM in isoform 2. 1 PublicationVSP_056340Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z79782 Genomic DNA. Translation: CAB02142.1.
    Y08456 Genomic DNA. Translation: CAA69712.1.
    U45983 Genomic DNA. Translation: AAB61962.1.
    AF005210 mRNA. Translation: AAB62547.1.
    U62556 Genomic DNA. Translation: AAB05542.1.
    D49919 mRNA. Translation: BAA23387.1.
    AY016370 Genomic DNA. Translation: AAK08628.1.
    AK314957 mRNA. Translation: BAG37461.1.
    AC104850 Genomic DNA. No translation available.
    CH471055 Genomic DNA. Translation: EAW64577.1.
    BC069067 mRNA. Translation: AAH69067.1.
    BC074743 mRNA. Translation: AAH74743.1.
    BC107152 mRNA. Translation: AAI07153.1.
    BC107159 mRNA. Translation: AAI07160.1.
    CCDSiCCDS2684.1.
    PIRiJC5067.
    RefSeqiNP_005192.1. NM_005201.3.
    UniGeneiHs.113222.

    Genome annotation databases

    EnsembliENST00000326306; ENSP00000326432; ENSG00000179934.
    ENST00000545843; ENSP00000440474; ENSG00000179934.
    GeneIDi1237.
    KEGGihsa:1237.
    UCSCiuc010hhr.2. human.

    Polymorphism databases

    DMDMi1707884.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Web resourcesi

    Wikipedia

    CC chemokine receptors entry

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z79782 Genomic DNA. Translation: CAB02142.1 .
    Y08456 Genomic DNA. Translation: CAA69712.1 .
    U45983 Genomic DNA. Translation: AAB61962.1 .
    AF005210 mRNA. Translation: AAB62547.1 .
    U62556 Genomic DNA. Translation: AAB05542.1 .
    D49919 mRNA. Translation: BAA23387.1 .
    AY016370 Genomic DNA. Translation: AAK08628.1 .
    AK314957 mRNA. Translation: BAG37461.1 .
    AC104850 Genomic DNA. No translation available.
    CH471055 Genomic DNA. Translation: EAW64577.1 .
    BC069067 mRNA. Translation: AAH69067.1 .
    BC074743 mRNA. Translation: AAH74743.1 .
    BC107152 mRNA. Translation: AAI07153.1 .
    BC107159 mRNA. Translation: AAI07160.1 .
    CCDSi CCDS2684.1.
    PIRi JC5067.
    RefSeqi NP_005192.1. NM_005201.3.
    UniGenei Hs.113222.

    3D structure databases

    ProteinModelPortali P51685.
    SMRi P51685. Positions 15-316.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-5836N.
    MINTi MINT-140630.
    STRINGi 9606.ENSP00000326432.

    Chemistry

    BindingDBi P51685.
    ChEMBLi CHEMBL4596.
    GuidetoPHARMACOLOGYi 65.

    Protein family/group databases

    GPCRDBi Search...

    PTM databases

    PhosphoSitei P51685.

    Polymorphism databases

    DMDMi 1707884.

    Proteomic databases

    PaxDbi P51685.
    PRIDEi P51685.

    Protocols and materials databases

    DNASUi 1237.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000326306 ; ENSP00000326432 ; ENSG00000179934 .
    ENST00000545843 ; ENSP00000440474 ; ENSG00000179934 .
    GeneIDi 1237.
    KEGGi hsa:1237.
    UCSCi uc010hhr.2. human.

    Organism-specific databases

    CTDi 1237.
    GeneCardsi GC03P039371.
    HGNCi HGNC:1609. CCR8.
    MIMi 601834. gene.
    neXtProti NX_P51685.
    PharmGKBi PA26173.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG149415.
    HOGENOMi HOG000234122.
    HOVERGENi HBG106917.
    InParanoidi P51685.
    KOi K04183.
    OMAi LIYATHV.
    OrthoDBi EOG7B5WW3.
    PhylomeDBi P51685.
    TreeFami TF330966.

    Enzyme and pathway databases

    Reactomei REACT_15344. Chemokine receptors bind chemokines.
    REACT_19231. G alpha (i) signalling events.

    Miscellaneous databases

    GeneWikii CCR8_(gene).
    GenomeRNAii 1237.
    NextBioi 5053.
    PROi P51685.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P51685.
    Bgeei P51685.
    CleanExi HS_CCR8.
    Genevestigatori P51685.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR004068. Chemokine_CCR8.
    IPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    PANTHERi PTHR24227. PTHR24227. 1 hit.
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00657. CCCHEMOKINER.
    PR01530. CHEMOKINER8.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning and RNA expression of two new human chemokine receptor-like genes."
      Zaballos A., Varona R., Gutierrez J., Lind P., Marquez G.
      Biochem. Biophys. Res. Commun. 227:846-853(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor."
      Samson M., Stordeur P., Labbe O., Soularue P., Vassart G., Parmentier M.
      Eur. J. Immunol. 26:3021-3028(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309."
      Tiffany H.L., Lautens L.L., Gao J.-L., Pease J., Locati M., Combadiere C., Modi W., Bonner T.I., Murphy P.M.
      J. Exp. Med. 186:165-170(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1), FUNCTION AS A RECEPTOR FOR CCL1.
      Tissue: Thymus.
    4. "Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues."
      Napolitano M., Zingoni A., Bernardini G., Spinetti G., Nista A., Storlazzi C.T., Rocchi M., Santoni A.
      J. Immunol. 157:2759-2763(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    5. "Molecular cloning of a human novel C-C chemokine receptor."
      Nakajima T., Yoshida R., Harada S.
      Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    6. "Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus."
      DeVries M.E., Cao H., Wang J., Xu L., Kelvin A.A., Ran L., Chau L.A., Madrenas J., Hegele R.A., Kelvin D.J.
      J. Biol. Chem. 278:11985-11994(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT GLY-27.
    7. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    8. "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
      , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
      Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    11. "Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor."
      Bernardini G., Hedrick J., Sozzani S., Luini W., Spinetti G., Weiss M., Menon S., Zlotnik A., Mantovani A., Santoni A., Napolitano M.
      Eur. J. Immunol. 28:582-588(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    12. "Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3."
      Goya I., Gutierrez J., Varona R., Kremer L., Zaballos A., Marquez G.
      J. Immunol. 160:1975-1981(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION AS A RECEPTOR FOR CCL1.
    13. "The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8."
      Garlisi C.G., Xiao H., Tian F., Hedrick J.A., Billah M.M., Egan R.W., Umland S.P.
      Eur. J. Immunol. 29:3210-3215(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiCCR8_HUMAN
    AccessioniPrimary (citable) accession number: P51685
    Secondary accession number(s): B2RC64
    , Q3KNQ8, Q3KNR3, Q9BYX5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 127 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human cell differentiation molecules
      CD nomenclature of surface proteins of human leucocytes and list of entries
    3. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    4. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    5. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    6. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    7. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3