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P51672 (XCL1_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lymphotactin
Alternative name(s):
C motif chemokine 1
Cytokine SCM-1
Small-inducible cytokine C1
Gene names
Name:Xcl1
Synonyms:Ltn, Scyc1
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length114 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Chemotactic activity for lymphocytes but not for monocytes or neutrophils By similarity.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the intercrine gamma family.

Ontologies

Keywords
   Biological processChemotaxis
   Cellular componentSecreted
   DomainSignal
   Molecular functionCytokine
   PTMDisulfide bond
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell chemotaxis

Inferred from electronic annotation. Source: GOC

immune response

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular space

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 11493Lymphotactin
PRO_0000005250

Amino acid modifications

Disulfide bond32 ↔ 69 Potential

Sequences

Sequence LengthMass (Da)Tools
P51672 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 8E171C14F63172B0

FASTA11412,370
        10         20         30         40         50         60 
MRLLLLTFLG VCCFAAWVVE GVGTEVLQES ICVSLRTQRL PVQKIKTYTI KEGAMRAVIF 

        70         80         90        100        110 
VTKRGLRICA DPQAKWVKTA IKTVDGRASA SKSKAETIPT QAQRSASTAV TLTG 

« Hide

References

[1]Jones M.L.
Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Long Evans.
Tissue: Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U23377 mRNA. Translation: AAA69478.1.
RefSeqNP_599188.1. NM_134361.1.
UniGeneRn.90962.

3D structure databases

ProteinModelPortalP51672.
SMRP51672. Positions 22-114.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000003976.

Proteomic databases

PaxDbP51672.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID171371.
KEGGrno:171371.
UCSCRGD:620452. rat.

Organism-specific databases

CTD6375.
RGD620452. Xcl1.

Phylogenomic databases

eggNOGNOG47852.
HOGENOMHOG000036685.
HOVERGENHBG102118.
InParanoidP51672.
KOK05507.
PhylomeDBP51672.

Gene expression databases

GenevestigatorP51672.

Family and domain databases

InterProIPR001811. Chemokine_IL8-like_dom.
IPR008105. Chemokine_XCL1.
[Graphical view]
PfamPF00048. IL8. 1 hit.
[Graphical view]
PRINTSPR01731. LYMPHOTACTIN.
SMARTSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMSSF54117. SSF54117. 1 hit.
ProtoNetSearch...

Other

NextBio622175.
PROP51672.

Entry information

Entry nameXCL1_RAT
AccessionPrimary (citable) accession number: P51672
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families