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P51672

- XCL1_RAT

UniProt

P51672 - XCL1_RAT

Protein

Lymphotactin

Gene

Xcl1

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Chemotactic activity for lymphocytes but not for monocytes or neutrophils.By similarity

    GO - Biological processi

    1. cell chemotaxis Source: GOC
    2. immune response Source: InterPro

    Keywords - Molecular functioni

    Cytokine

    Keywords - Biological processi

    Chemotaxis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lymphotactin
    Alternative name(s):
    C motif chemokine 1
    Cytokine SCM-1
    Small-inducible cytokine C1
    Gene namesi
    Name:Xcl1
    Synonyms:Ltn, Scyc1
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Unplaced

    Organism-specific databases

    RGDi620452. Xcl1.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-KW

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 11493LymphotactinPRO_0000005250Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi32 ↔ 69Sequence Analysis

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PaxDbiP51672.

    Expressioni

    Gene expression databases

    GenevestigatoriP51672.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000003976.

    Structurei

    3D structure databases

    ProteinModelPortaliP51672.
    SMRiP51672. Positions 22-114.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the intercrine gamma family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG47852.
    HOGENOMiHOG000036685.
    HOVERGENiHBG102118.
    InParanoidiP51672.
    KOiK05507.
    PhylomeDBiP51672.

    Family and domain databases

    InterProiIPR001811. Chemokine_IL8-like_dom.
    IPR008105. Chemokine_XCL1.
    [Graphical view]
    PfamiPF00048. IL8. 1 hit.
    [Graphical view]
    PRINTSiPR01731. LYMPHOTACTIN.
    SMARTiSM00199. SCY. 1 hit.
    [Graphical view]
    SUPFAMiSSF54117. SSF54117. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P51672-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLLLLTFLG VCCFAAWVVE GVGTEVLQES ICVSLRTQRL PVQKIKTYTI    50
    KEGAMRAVIF VTKRGLRICA DPQAKWVKTA IKTVDGRASA SKSKAETIPT 100
    QAQRSASTAV TLTG 114
    Length:114
    Mass (Da):12,370
    Last modified:October 1, 1996 - v1
    Checksum:i8E171C14F63172B0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U23377 mRNA. Translation: AAA69478.1.
    RefSeqiNP_599188.1. NM_134361.1.
    UniGeneiRn.90962.

    Genome annotation databases

    GeneIDi171371.
    KEGGirno:171371.
    UCSCiRGD:620452. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U23377 mRNA. Translation: AAA69478.1 .
    RefSeqi NP_599188.1. NM_134361.1.
    UniGenei Rn.90962.

    3D structure databases

    ProteinModelPortali P51672.
    SMRi P51672. Positions 22-114.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000003976.

    Proteomic databases

    PaxDbi P51672.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 171371.
    KEGGi rno:171371.
    UCSCi RGD:620452. rat.

    Organism-specific databases

    CTDi 6375.
    RGDi 620452. Xcl1.

    Phylogenomic databases

    eggNOGi NOG47852.
    HOGENOMi HOG000036685.
    HOVERGENi HBG102118.
    InParanoidi P51672.
    KOi K05507.
    PhylomeDBi P51672.

    Miscellaneous databases

    NextBioi 622175.
    PROi P51672.

    Gene expression databases

    Genevestigatori P51672.

    Family and domain databases

    InterProi IPR001811. Chemokine_IL8-like_dom.
    IPR008105. Chemokine_XCL1.
    [Graphical view ]
    Pfami PF00048. IL8. 1 hit.
    [Graphical view ]
    PRINTSi PR01731. LYMPHOTACTIN.
    SMARTi SM00199. SCY. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54117. SSF54117. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Jones M.L.
      Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: Long Evans.
      Tissue: Lung.

    Entry informationi

    Entry nameiXCL1_RAT
    AccessioniPrimary (citable) accession number: P51672
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3