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P51672

- XCL1_RAT

UniProt

P51672 - XCL1_RAT

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Protein
Lymphotactin
Gene
Xcl1, Ltn, Scyc1
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Chemotactic activity for lymphocytes but not for monocytes or neutrophils By similarity.

GO - Biological processi

  1. cell chemotaxis Source: GOC
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Cytokine

Keywords - Biological processi

Chemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Lymphotactin
Alternative name(s):
C motif chemokine 1
Cytokine SCM-1
Small-inducible cytokine C1
Gene namesi
Name:Xcl1
Synonyms:Ltn, Scyc1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi620452. Xcl1.

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed prediction
Add
BLAST
Chaini22 – 11493Lymphotactin
PRO_0000005250Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi32 ↔ 69 Reviewed prediction

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP51672.

Expressioni

Gene expression databases

GenevestigatoriP51672.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000003976.

Structurei

3D structure databases

ProteinModelPortaliP51672.
SMRiP51672. Positions 22-114.

Family & Domainsi

Sequence similaritiesi

Belongs to the intercrine gamma family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG47852.
HOGENOMiHOG000036685.
HOVERGENiHBG102118.
InParanoidiP51672.
KOiK05507.
PhylomeDBiP51672.

Family and domain databases

InterProiIPR001811. Chemokine_IL8-like_dom.
IPR008105. Chemokine_XCL1.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
PRINTSiPR01731. LYMPHOTACTIN.
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P51672-1 [UniParc]FASTAAdd to Basket

« Hide

MRLLLLTFLG VCCFAAWVVE GVGTEVLQES ICVSLRTQRL PVQKIKTYTI    50
KEGAMRAVIF VTKRGLRICA DPQAKWVKTA IKTVDGRASA SKSKAETIPT 100
QAQRSASTAV TLTG 114
Length:114
Mass (Da):12,370
Last modified:October 1, 1996 - v1
Checksum:i8E171C14F63172B0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U23377 mRNA. Translation: AAA69478.1.
RefSeqiNP_599188.1. NM_134361.1.
UniGeneiRn.90962.

Genome annotation databases

GeneIDi171371.
KEGGirno:171371.
UCSCiRGD:620452. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U23377 mRNA. Translation: AAA69478.1 .
RefSeqi NP_599188.1. NM_134361.1.
UniGenei Rn.90962.

3D structure databases

ProteinModelPortali P51672.
SMRi P51672. Positions 22-114.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000003976.

Proteomic databases

PaxDbi P51672.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 171371.
KEGGi rno:171371.
UCSCi RGD:620452. rat.

Organism-specific databases

CTDi 6375.
RGDi 620452. Xcl1.

Phylogenomic databases

eggNOGi NOG47852.
HOGENOMi HOG000036685.
HOVERGENi HBG102118.
InParanoidi P51672.
KOi K05507.
PhylomeDBi P51672.

Miscellaneous databases

NextBioi 622175.
PROi P51672.

Gene expression databases

Genevestigatori P51672.

Family and domain databases

InterProi IPR001811. Chemokine_IL8-like_dom.
IPR008105. Chemokine_XCL1.
[Graphical view ]
Pfami PF00048. IL8. 1 hit.
[Graphical view ]
PRINTSi PR01731. LYMPHOTACTIN.
SMARTi SM00199. SCY. 1 hit.
[Graphical view ]
SUPFAMi SSF54117. SSF54117. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Jones M.L.
    Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Long Evans.
    Tissue: Lung.

Entry informationi

Entry nameiXCL1_RAT
AccessioniPrimary (citable) accession number: P51672
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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