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P51546

- KGCY_HEDDI

UniProt

P51546 - KGCY_HEDDI

Protein

Glycocyamine kinase

Gene
N/A
Organism
Hediste diversicolor (Sandworm) (Nereis diversicolor)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + guanidinoacetate = ADP + phosphoguanidinoacetate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei186 – 1861ATPPROSITE-ProRule annotation
    Binding sitei231 – 2311ATPPROSITE-ProRule annotation
    Binding sitei330 – 3301ATPPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi123 – 1275ATPPROSITE-ProRule annotation
    Nucleotide bindingi287 – 2915ATPPROSITE-ProRule annotation
    Nucleotide bindingi315 – 3206ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. guanidinoacetate kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycocyamine kinase (EC:2.7.3.1)
    Short name:
    GK
    Alternative name(s):
    Guanidinoacetate kinase
    OrganismiHediste diversicolor (Sandworm) (Nereis diversicolor)
    Taxonomic identifieri126592 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaNereididaeHedisteHediste diversicolor species group

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Glycocyamine kinasePRO_0000212008Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.

    Structurei

    3D structure databases

    ProteinModelPortaliP51546.
    SMRiP51546. Positions 14-368.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 9488Phosphagen kinase N-terminalPROSITE-ProRule annotationAdd
    BLAST
    Domaini120 – 362243Phosphagen kinase C-terminalPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ATP:guanido phosphotransferase family.PROSITE-ProRule annotation
    Contains 1 phosphagen kinase C-terminal domain.PROSITE-ProRule annotation
    Contains 1 phosphagen kinase N-terminal domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.135.10. 1 hit.
    3.30.590.10. 1 hit.
    InterProiIPR022415. ATP-guanido_PTrfase_AS.
    IPR022414. ATP-guanido_PTrfase_cat.
    IPR022413. ATP-guanido_PTrfase_N.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    [Graphical view]
    PfamiPF00217. ATP-gua_Ptrans. 1 hit.
    PF02807. ATP-gua_PtransN. 1 hit.
    [Graphical view]
    SUPFAMiSSF48034. SSF48034. 1 hit.
    PROSITEiPS00112. PHOSPHAGEN_KINASE. 1 hit.
    PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
    PS51509. PHOSPHAGEN_KINASE_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P51546-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFKDYSREKF AKENFPDLSK HNNVMASHLT YELYEKYWDK VTPNGVTLDK    50
    CIQTGVDNPG NKFYGKKTGC VFGDEHSYET FKDFFDRVIE EIHHFKPEDV 100
    HPATDLDETK LVGGVFDEKY VKSCRIRCGR SVRGVCLPPA MSRAERRLVE 150
    KVVSNALGGL KEDLAGKYFP LTTMNDKDME ALIEDHFLFE KPTGALLTTS 200
    GCARDWPDGR GIWHNNGKNF LVWINEEDHI RIISMQKGGD MRAVFSRFGR 250
    GLTEVERLMK EKGYELMRNE RLGYICTCPT NLGTVVRASV HLRLANLEKD 300
    KRFDDFLAKL RLGKRGTGGE SSLAEDSTYD ISNLARLGKS ERELVQVLVD 350
    GVNVLIEADK RLEAGKPIDD LTPRLNSSTG TSISATASRH MTL 393
    Length:393
    Mass (Da):44,462
    Last modified:October 1, 1996 - v1
    Checksum:iCB529ADC9B3CCFC1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D26103 mRNA. Translation: BAA05099.1.
    PIRiS77896.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D26103 mRNA. Translation: BAA05099.1 .
    PIRi S77896.

    3D structure databases

    ProteinModelPortali P51546.
    SMRi P51546. Positions 14-368.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.135.10. 1 hit.
    3.30.590.10. 1 hit.
    InterProi IPR022415. ATP-guanido_PTrfase_AS.
    IPR022414. ATP-guanido_PTrfase_cat.
    IPR022413. ATP-guanido_PTrfase_N.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    [Graphical view ]
    Pfami PF00217. ATP-gua_Ptrans. 1 hit.
    PF02807. ATP-gua_PtransN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48034. SSF48034. 1 hit.
    PROSITEi PS00112. PHOSPHAGEN_KINASE. 1 hit.
    PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
    PS51509. PHOSPHAGEN_KINASE_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of phosphagen kinase. Primary structure of glycocyamine kinase and arginine kinase from invertebrates."
      Suzuki T., Furukohri T.
      J. Mol. Biol. 237:353-357(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiKGCY_HEDDI
    AccessioniPrimary (citable) accession number: P51546
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3