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P51546 (KGCY_HEDDI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycocyamine kinase

Short name=GK
EC=2.7.3.1
Alternative name(s):
Guanidinoacetate kinase
OrganismHediste diversicolor (Sandworm) (Nereis diversicolor)
Taxonomic identifier126592 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaNereididaeHedisteHediste diversicolor species group

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + guanidinoacetate = ADP + phosphoguanidinoacetate.

Subunit structure

Monomer.

Sequence similarities

Belongs to the ATP:guanido phosphotransferase family.

Contains 1 phosphagen kinase C-terminal domain.

Contains 1 phosphagen kinase N-terminal domain.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

guanidinoacetate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Glycocyamine kinase
PRO_0000212008

Regions

Domain7 – 9488Phosphagen kinase N-terminal
Domain120 – 362243Phosphagen kinase C-terminal
Nucleotide binding123 – 1275ATP By similarity
Nucleotide binding287 – 2915ATP By similarity
Nucleotide binding315 – 3206ATP By similarity

Sites

Binding site1861ATP By similarity
Binding site2311ATP By similarity
Binding site3301ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P51546 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: CB529ADC9B3CCFC1

FASTA39344,462
        10         20         30         40         50         60 
MFKDYSREKF AKENFPDLSK HNNVMASHLT YELYEKYWDK VTPNGVTLDK CIQTGVDNPG 

        70         80         90        100        110        120 
NKFYGKKTGC VFGDEHSYET FKDFFDRVIE EIHHFKPEDV HPATDLDETK LVGGVFDEKY 

       130        140        150        160        170        180 
VKSCRIRCGR SVRGVCLPPA MSRAERRLVE KVVSNALGGL KEDLAGKYFP LTTMNDKDME 

       190        200        210        220        230        240 
ALIEDHFLFE KPTGALLTTS GCARDWPDGR GIWHNNGKNF LVWINEEDHI RIISMQKGGD 

       250        260        270        280        290        300 
MRAVFSRFGR GLTEVERLMK EKGYELMRNE RLGYICTCPT NLGTVVRASV HLRLANLEKD 

       310        320        330        340        350        360 
KRFDDFLAKL RLGKRGTGGE SSLAEDSTYD ISNLARLGKS ERELVQVLVD GVNVLIEADK 

       370        380        390 
RLEAGKPIDD LTPRLNSSTG TSISATASRH MTL 

« Hide

References

[1]"Evolution of phosphagen kinase. Primary structure of glycocyamine kinase and arginine kinase from invertebrates."
Suzuki T., Furukohri T.
J. Mol. Biol. 237:353-357(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D26103 mRNA. Translation: BAA05099.1.
PIRS77896.

3D structure databases

ProteinModelPortalP51546.
SMRP51546. Positions 14-368.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.135.10. 1 hit.
3.30.590.10. 1 hit.
InterProIPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR022413. ATP-guanido_PTrfase_N.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PfamPF00217. ATP-gua_Ptrans. 1 hit.
PF02807. ATP-gua_PtransN. 1 hit.
[Graphical view]
SUPFAMSSF48034. SSF48034. 1 hit.
PROSITEPS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
PS51509. PHOSPHAGEN_KINASE_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGCY_HEDDI
AccessionPrimary (citable) accession number: P51546
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families