ZNF83

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	Length	Description	Actions
Zinc fingerⁱ	93 – 115	23	C2H2-type 1; degeneratePROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	121 – 143	23	C2H2-type 2PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	149 – 171	23	C2H2-type 3PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	177 – 199	23	C2H2-type 4PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	205 – 227	23	C2H2-type 5PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	233 – 255	23	C2H2-type 6PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	261 – 283	23	C2H2-type 7PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	289 – 311	23	C2H2-type 8PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	317 – 339	23	C2H2-type 9PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	345 – 367	23	C2H2-type 10PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	373 – 395	23	C2H2-type 11PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	401 – 423	23	C2H2-type 12PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	429 – 451	23	C2H2-type 13PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	457 – 479	23	C2H2-type 14PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	485 – 507	23	C2H2-type 15PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 83 Alternative name(s): Zinc finger protein 816B Zinc finger protein HPF1
Gene namesⁱ	Name:ZNF83 Synonyms:ZNF816B
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

HGNCⁱ	HGNC:13158. ZNF83.

HGNCⁱ

HGNC:13158. ZNF83.

Subcellular locationⁱ

Nucleus Curated

GO - Cellular componentⁱ

nucleus Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA37731.

PharmGKBⁱ

PA37731.

Polymorphism and mutation databases

BioMutaⁱ	ZNF83.
DMDMⁱ	300669707.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Chainⁱ	1 – 516	516	Zinc finger protein 83		PRO_0000047396	Add BLAST

Proteomic databases

PaxDbⁱ	P51522.
PeptideAtlasⁱ	P51522.
PRIDEⁱ	P51522.

PTM databases

iPTMnetⁱ	P51522.
PhosphoSiteⁱ	P51522.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000167766.
CleanExⁱ	HS_ZNF83.
ExpressionAtlasⁱ	P51522. baseline and differential.
Genevisibleⁱ	P51522. HS.

Organism-specific databases

HPAⁱ	HPA025970.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	120886. 3 interactions.
IntActⁱ	P51522. 4 interactions.
MINTⁱ	MINT-1182660.
STRINGⁱ	9606.ENSP00000301096.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P51522.
SMRⁱ	P51522. Positions 29-67, 93-515.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Contains 15 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature key	Position(s)	Length	Description	Actions
Zinc fingerⁱ	93 – 115	23	C2H2-type 1; degeneratePROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	121 – 143	23	C2H2-type 2PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	149 – 171	23	C2H2-type 3PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	177 – 199	23	C2H2-type 4PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	205 – 227	23	C2H2-type 5PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	233 – 255	23	C2H2-type 6PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	261 – 283	23	C2H2-type 7PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	289 – 311	23	C2H2-type 8PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	317 – 339	23	C2H2-type 9PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	345 – 367	23	C2H2-type 10PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	373 – 395	23	C2H2-type 11PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	401 – 423	23	C2H2-type 12PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	429 – 451	23	C2H2-type 13PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	457 – 479	23	C2H2-type 14PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST
Zinc fingerⁱ	485 – 507	23	C2H2-type 15PROSITE-ProRule annotation Manual assertion according to rulesⁱ PROSITE-ProRule:PRU00042	Add BLAST

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
GeneTreeⁱ	ENSGT00690000102079.
HOGENOMⁱ	HOG000234617.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P51522.
KOⁱ	K09228.
OMAⁱ	FTQKEKA.
OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P51522.
TreeFamⁱ	TF341892.

Family and domain databases

Gene3Dⁱ	3.30.160.60. 15 hits.
InterProⁱ	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Pfamⁱ	PF00096. zf-C2H2. 8 hits. [Graphical view]
SMARTⁱ	SM00355. ZnF_C2H2. 15 hits. [Graphical view]
PROSITEⁱ	PS00028. ZINC_FINGER_C2H2_1. 14 hits. PS50157. ZINC_FINGER_C2H2_2. 15 hits. [Graphical view]

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: P51522-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MHGRKDDAQK QPVKNQLGLN PQSHLPELQL FQAEGKIYKY DHMEKSVNSS 
        60         70         80         90        100
SLVSPPQRIS STVKTHISHT YECNFVDSLF TQKEKANIGT EHYKCSERGK 
       110        120        130        140        150
AFHQGLHFTI HQIIHTKETQ FKCDICGKIF NKKSNLASHQ RIHTGEKPYK 
       160        170        180        190        200
CNECGKVFHN MSHLAQHRRI HTGEKPYKCN ECGKVFNQIS HLAQHQRIHT 
       210        220        230        240        250
GEKPYKCNEC GKVFHQISHL AQHRTIHTGE KPYECNKCGK VFSRNSYLVQ 
       260        270        280        290        300
HLIIHTGEKP YRCNVCGKVF HHISHLAQHQ RIHTGEKPYK CNECGKVFSH 
       310        320        330        340        350
KSSLVNHWRI HTGEKPYKCN ECGKVFSHKS SLVNHWRIHT GEKPYKCNEC 
       360        370        380        390        400
GKVFSRNSYL AQHLIIHAGE KPYKCDECDK AFSQNSHLVQ HHRIHTGEKP 
       410        420        430        440        450
YKCDECGKVF SQNSYLAYHW RIHTGEKAYK CNECGKVFGL NSSLAHHRKI 
       460        470        480        490        500
HTGEKPFKCN ECGKAFSMRS SLTNHHAIHT GEKHFKCNEC GKLFRDNSYL 
       510 
VRHQRFHAGK KSNTCN

Length:516

Mass (Da):59,710

Last modified:July 13, 2010 - v3

Checksum:ⁱA6CA428CFAEA5D69

GO

Isoform 2 (identifier: P51522-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
271-298: Missing.

« Hide

        10         20         30         40         50
MHGRKDDAQK QPVKNQLGLN PQSHLPELQL FQAEGKIYKY DHMEKSVNSS 
        60         70         80         90        100
SLVSPPQRIS STVKTHISHT YECNFVDSLF TQKEKANIGT EHYKCSERGK 
       110        120        130        140        150
AFHQGLHFTI HQIIHTKETQ FKCDICGKIF NKKSNLASHQ RIHTGEKPYK 
       160        170        180        190        200
CNECGKVFHN MSHLAQHRRI HTGEKPYKCN ECGKVFNQIS HLAQHQRIHT 
       210        220        230        240        250
GEKPYKCNEC GKVFHQISHL AQHRTIHTGE KPYECNKCGK VFSRNSYLVQ 
       260        270        280        290        300
HLIIHTGEKP YRCNVCGKVF SHKSSLVNHW RIHTGEKPYK CNECGKVFSH 
       310        320        330        340        350
KSSLVNHWRI HTGEKPYKCN ECGKVFSRNS YLAQHLIIHA GEKPYKCDEC 
       360        370        380        390        400
DKAFSQNSHL VQHHRIHTGE KPYKCDECGK VFSQNSYLAY HWRIHTGEKA 
       410        420        430        440        450
YKCNECGKVF GLNSSLAHHR KIHTGEKPFK CNECGKAFSM RSSLTNHHAI 
       460        470        480 
HTGEKHFKCN ECGKLFRDNS YLVRHQRFHA GKKSNTCN

Show »

Length:488

Mass (Da):56,429

Checksum:ⁱ02D19C75A1677C48

GO

Experimental Info

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Sequence conflictⁱ	89 – 91	3	GTE → MDR in AAG41760 (PubMed:2505992).Curated
Sequence conflictⁱ	108 – 109	2	FT → LP in AAG41760 (PubMed:2505992).Curated

Natural variant

Feature key	Position(s)	Length	Description	Feature identifier
Natural variantⁱ	70 – 70	1	T → I. Corresponds to variant rs3786490 [ dbSNP \| Ensembl ].	VAR_058206
Natural variantⁱ	96 – 96	1	S → N.3 Publications Manual assertion based on experiment inⁱ Ref.1 "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT ASN-96. Ref.3 "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS ASN-96 AND ARG-392. Ref.4 "The human genome contains hundreds of genes coding for finger proteins of the Kruppel type." Bellefroid E.J., Lecocq P.J., Benhida A., Poncelet D.A., Belayew A., Martial J.A. DNA 8:377-387(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 89-428 (ISOFORM 1), VARIANT ASN-96. Corresponds to variant rs1056185 [ dbSNP \| Ensembl ].	VAR_058207
Natural variantⁱ	119 – 119	1	T → M. Corresponds to variant rs329940 [ dbSNP \| Ensembl ].	VAR_058208
Natural variantⁱ	392 – 392	1	H → R.1 Publication Manual assertion based on experiment inⁱ Ref.3 "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS ASN-96 AND ARG-392. Corresponds to variant rs11545619 [ dbSNP \| Ensembl ].	VAR_058209

Alternative sequence

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Alternative sequenceⁱ	271 – 298	28	Missing in isoform 2. 2 Publications Manual assertion based on opinion inⁱ Ref.1 "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT ASN-96. Ref.3 "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS ASN-96 AND ARG-392.		VSP_037663	Add BLAST

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK289399 mRNA. Translation: BAF82088.1. AC022150 Genomic DNA. No translation available. BC050407 mRNA. Translation: AAH50407.1. BC032867 mRNA. Translation: AAH32867.1. M27877 mRNA. Translation: AAG41760.1.
CCDSⁱ	CCDS12854.1. [P51522-1]
PIRⁱ	A32891.
RefSeqⁱ	NP_001099019.1. NM_001105549.1. [P51522-1] NP_001099020.1. NM_001105550.1. [P51522-1] NP_001099021.1. NM_001105551.1. [P51522-1] NP_001099022.1. NM_001105552.1. [P51522-1] NP_001264874.1. NM_001277945.1. [P51522-1] NP_001264875.1. NM_001277946.1. [P51522-1] NP_001264876.1. NM_001277947.1. [P51522-1] NP_001264877.1. NM_001277948.1. [P51522-1] NP_001264878.1. NM_001277949.1. [P51522-1] NP_001264880.1. NM_001277951.1. [P51522-1] NP_001264881.1. NM_001277952.1. [P51522-1] NP_060770.3. NM_018300.3. [P51522-1]
UniGeneⁱ	Hs.467210. Hs.659798. Hs.665751. Hs.710125. Hs.744177.

Genome annotation databases

Ensemblⁱ	ENST00000301096; ENSP00000301096; ENSG00000167766. [P51522-1] ENST00000536937; ENSP00000445993; ENSG00000167766. [P51522-1] ENST00000541777; ENSP00000439681; ENSG00000167766. [P51522-1] ENST00000545872; ENSP00000440713; ENSG00000167766. [P51522-1] ENST00000597597; ENSP00000472619; ENSG00000167766. [P51522-1]
GeneIDⁱ	55769.
KEGGⁱ	hsa:55769.
UCSCⁱ	uc002pzu.5. human. [P51522-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK289399 mRNA. Translation: BAF82088.1. AC022150 Genomic DNA. No translation available. BC050407 mRNA. Translation: AAH50407.1. BC032867 mRNA. Translation: AAH32867.1. M27877 mRNA. Translation: AAG41760.1.
CCDSⁱ	CCDS12854.1. [P51522-1]
PIRⁱ	A32891.
RefSeqⁱ	NP_001099019.1. NM_001105549.1. [P51522-1] NP_001099020.1. NM_001105550.1. [P51522-1] NP_001099021.1. NM_001105551.1. [P51522-1] NP_001099022.1. NM_001105552.1. [P51522-1] NP_001264874.1. NM_001277945.1. [P51522-1] NP_001264875.1. NM_001277946.1. [P51522-1] NP_001264876.1. NM_001277947.1. [P51522-1] NP_001264877.1. NM_001277948.1. [P51522-1] NP_001264878.1. NM_001277949.1. [P51522-1] NP_001264880.1. NM_001277951.1. [P51522-1] NP_001264881.1. NM_001277952.1. [P51522-1] NP_060770.3. NM_018300.3. [P51522-1]
UniGeneⁱ	Hs.467210. Hs.659798. Hs.665751. Hs.710125. Hs.744177.

3D structure databases

ProteinModelPortalⁱ	P51522.
SMRⁱ	P51522. Positions 29-67, 93-515.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	120886. 3 interactions.
IntActⁱ	P51522. 4 interactions.
MINTⁱ	MINT-1182660.
STRINGⁱ	9606.ENSP00000301096.

PTM databases

iPTMnetⁱ	P51522.
PhosphoSiteⁱ	P51522.

Polymorphism and mutation databases

BioMutaⁱ	ZNF83.
DMDMⁱ	300669707.

Proteomic databases

PaxDbⁱ	P51522.
PeptideAtlasⁱ	P51522.
PRIDEⁱ	P51522.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000301096; ENSP00000301096; ENSG00000167766. [P51522-1] ENST00000536937; ENSP00000445993; ENSG00000167766. [P51522-1] ENST00000541777; ENSP00000439681; ENSG00000167766. [P51522-1] ENST00000545872; ENSP00000440713; ENSG00000167766. [P51522-1] ENST00000597597; ENSP00000472619; ENSG00000167766. [P51522-1]
GeneIDⁱ	55769.
KEGGⁱ	hsa:55769.
UCSCⁱ	uc002pzu.5. human. [P51522-1]

Organism-specific databases

CTDⁱ	55769.
GeneCardsⁱ	ZNF83.
HGNCⁱ	HGNC:13158. ZNF83.
HPAⁱ	HPA025970.
MIMⁱ	194558. gene.
neXtProtⁱ	NX_P51522.
PharmGKBⁱ	PA37731.
GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
GeneTreeⁱ	ENSGT00690000102079.
HOGENOMⁱ	HOG000234617.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P51522.
KOⁱ	K09228.
OMAⁱ	FTQKEKA.
OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P51522.
TreeFamⁱ	TF341892.

Miscellaneous databases

ChiTaRSⁱ	ZNF83. human.
GeneWikiⁱ	ZNF83.
GenomeRNAiⁱ	55769.
PROⁱ	P51522.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000167766.
CleanExⁱ	HS_ZNF83.
ExpressionAtlasⁱ	P51522. baseline and differential.
Genevisibleⁱ	P51522. HS.

Family and domain databases

Gene3Dⁱ	3.30.160.60. 15 hits.
InterProⁱ	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Pfamⁱ	PF00096. zf-C2H2. 8 hits. [Graphical view]
SMARTⁱ	SM00355. ZnF_C2H2. 15 hits. [Graphical view]
PROSITEⁱ	PS00028. ZINC_FINGER_C2H2_1. 14 hits. PS50157. ZINC_FINGER_C2H2_2. 15 hits. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

ZNF83_HUMAN

Accessionⁱ

Primary (citable) accession number: P51522
Secondary accession number(s): A8MT75, Q3ZCX0, Q6PI08

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	July 13, 2010
Last modified:	September 7, 2016
This is version 145 of the entry and version 3 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P51522 (ZNF83_HUMAN)

UniProt

P51522 - ZNF83_HUMAN

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Zinc finger protein 83

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Provides information on the disease(s) and phenotype(s) associated with a protein.</p><p><a href='../manual/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequences (2)i

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequences (2)ⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ