ID   ARRB_CALVI              Reviewed;         401 AA.
AC   P51487;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   22-FEB-2023, entry version 66.
DE   RecName: Full=Phosrestin-1;
DE   AltName: Full=Arrestin-2;
DE   AltName: Full=Arrestin-B;
DE   AltName: Full=Phosrestin I;
GN   Name=ARR2;
OS   Calliphora vicina (Blue blowfly) (Calliphora erythrocephala).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Calliphoridae; Calliphorinae; Calliphora.
OX   NCBI_TaxID=7373;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 2-11.
RC   TISSUE=Retina;
RX   PubMed=7929436; DOI=10.1016/s0021-9258(18)47113-x;
RA   Plangger A., Malicki D., Whitney M., Paulsen R.;
RT   "Mechanism of arrestin 2 function in rhabdomeric photoreceptors.";
RL   J. Biol. Chem. 269:26969-26975(1994).
CC   -!- FUNCTION: Directly interacts with light-activated rhodopsin thereby
CC       activating the phosphorylation of metarhodopsin. Inhibits the
CC       dephosphorylation of metarhodopsin.
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; X79073; CAA55673.1; -; mRNA.
DR   PIR; B55081; B55081.
DR   AlphaFoldDB; P51487; -.
DR   SMR; P51487; -.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   Gene3D; 2.60.40.840; -; 1.
DR   InterPro; IPR000698; Arrestin.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR017864; Arrestin_CS.
DR   InterPro; IPR014753; Arrestin_N.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11792; ARRESTIN; 1.
DR   PANTHER; PTHR11792:SF23; PHOSRESTIN-1; 1.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   PRINTS; PR00309; ARRESTIN.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; E set domains; 2.
DR   PROSITE; PS00295; ARRESTINS; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Phosphoprotein; Sensory transduction; Vision.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:7929436"
FT   CHAIN           2..401
FT                   /note="Phosrestin-1"
FT                   /id="PRO_0000205216"
SQ   SEQUENCE   401 AA;  44912 MW;  1212C2422CD35A94 CRC64;
     MVVSVKVFKK ATPNGKVTFY LGRRHFIDHF DYIDPVDGVI VVDPDYLKNR KVFAQLATIY
     RYGREEDEVM GVKFSKELIL CREQIVPMGN SNMEMTPTQE KLVRKLGSNA HPFTFHFPPN
     SPSSVTLQQE GDDLGKPLGV EYTIRAYVAD SEDDRQHKRS MVSLVIKKLQ YAPPTRGQRL
     PSSLVSKGFT FSNGKISLEV TLDREIYYHG GKVAATVQIN NNSKKAVKNI KVFIIQHTEI
     TMVNAQFSKH VAQLETKEGC PITPGANLSK TFYLIPLASN NKDRHGIALD GHLKDEDVNL
     ASSTMVQDGK STGDACGIVI SYSVRIKLNC GTLGGEIQTD VPFKLLQPAP GSVEKKRSNA
     MKKMKSIEQH RNTKGYYQDD DDNIVFEDFA KMRNNNADVM D
//