Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosrestin-1

Gene

ARR2

Organism
Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Directly interacts with light-activated rhodopsin thereby activating the phosphorylation of metarhodopsin. Inhibits the dephosphorylation of metarhodopsin.

GO - Biological processi

  1. signal transduction Source: InterPro
  2. visual perception Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Sensory transduction, Vision

Names & Taxonomyi

Protein namesi
Recommended name:
Phosrestin-1
Alternative name(s):
Arrestin-2
Arrestin-B
Phosrestin I
Gene namesi
Name:ARR2
OrganismiCalliphora vicina (Blue blowfly) (Calliphora erythrocephala)
Taxonomic identifieri7373 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaCalliphoridaeCalliphorinaeCalliphora

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 401400Phosrestin-1PRO_0000205216Add
BLAST

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP51487.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arrestin family.Curated

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
2.60.40.840. 1 hit.
InterProiIPR000698. Arrestin.
IPR011021. Arrestin-like_N.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR017864. Arrestin_CS.
IPR014753. Arrestin_N.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
PF00339. Arrestin_N. 1 hit.
[Graphical view]
PRINTSiPR00309. ARRESTIN.
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 2 hits.
PROSITEiPS00295. ARRESTINS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P51487-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVSVKVFKK ATPNGKVTFY LGRRHFIDHF DYIDPVDGVI VVDPDYLKNR
60 70 80 90 100
KVFAQLATIY RYGREEDEVM GVKFSKELIL CREQIVPMGN SNMEMTPTQE
110 120 130 140 150
KLVRKLGSNA HPFTFHFPPN SPSSVTLQQE GDDLGKPLGV EYTIRAYVAD
160 170 180 190 200
SEDDRQHKRS MVSLVIKKLQ YAPPTRGQRL PSSLVSKGFT FSNGKISLEV
210 220 230 240 250
TLDREIYYHG GKVAATVQIN NNSKKAVKNI KVFIIQHTEI TMVNAQFSKH
260 270 280 290 300
VAQLETKEGC PITPGANLSK TFYLIPLASN NKDRHGIALD GHLKDEDVNL
310 320 330 340 350
ASSTMVQDGK STGDACGIVI SYSVRIKLNC GTLGGEIQTD VPFKLLQPAP
360 370 380 390 400
GSVEKKRSNA MKKMKSIEQH RNTKGYYQDD DDNIVFEDFA KMRNNNADVM

D
Length:401
Mass (Da):44,912
Last modified:January 23, 2007 - v2
Checksum:i1212C2422CD35A94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79073 mRNA. Translation: CAA55673.1.
PIRiB55081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79073 mRNA. Translation: CAA55673.1.
PIRiB55081.

3D structure databases

ProteinModelPortaliP51487.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
2.60.40.840. 1 hit.
InterProiIPR000698. Arrestin.
IPR011021. Arrestin-like_N.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR017864. Arrestin_CS.
IPR014753. Arrestin_N.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
PF00339. Arrestin_N. 1 hit.
[Graphical view]
PRINTSiPR00309. ARRESTIN.
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 2 hits.
PROSITEiPS00295. ARRESTINS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Mechanism of arrestin 2 function in rhabdomeric photoreceptors."
    Plangger A., Malicki D., Whitney M., Paulsen R.
    J. Biol. Chem. 269:26969-26975(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-11.
    Tissue: Retina.

Entry informationi

Entry nameiARRB_CALVI
AccessioniPrimary (citable) accession number: P51487
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.