P51487 (ARRB_CALVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosrestin-1

Alternative name(s):
Arrestin-2
Arrestin-B
Phosrestin I

Gene names

Name:

ARR2

Organism

Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)

Taxonomic identifier

7373 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Calyptratae › Oestroidea › Calliphoridae › Calliphorinae › Calliphora

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Directly interacts with light-activated rhodopsin thereby activating the phosphorylation of metarhodopsin. Inhibits the dephosphorylation of metarhodopsin.
Sequence similarities	Belongs to the arrestin family.

Ontologies

Keywords
Biological process	Sensory transduction Vision
PTM	Phosphoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	signal transduction Inferred from electronic annotation. Source: InterPro visual perception Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 401	400	Phosrestin-1		PRO_0000205216

Sequences

	Sequence		Length	Mass (Da)
	P51487 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 1212C2422CD35A94	FASTA	401	44,912
	10 20 30 40 50 60 MVVSVKVFKK ATPNGKVTFY LGRRHFIDHF DYIDPVDGVI VVDPDYLKNR KVFAQLATIY 70 80 90 100 110 120 RYGREEDEVM GVKFSKELIL CREQIVPMGN SNMEMTPTQE KLVRKLGSNA HPFTFHFPPN 130 140 150 160 170 180 SPSSVTLQQE GDDLGKPLGV EYTIRAYVAD SEDDRQHKRS MVSLVIKKLQ YAPPTRGQRL 190 200 210 220 230 240 PSSLVSKGFT FSNGKISLEV TLDREIYYHG GKVAATVQIN NNSKKAVKNI KVFIIQHTEI 250 260 270 280 290 300 TMVNAQFSKH VAQLETKEGC PITPGANLSK TFYLIPLASN NKDRHGIALD GHLKDEDVNL 310 320 330 340 350 360 ASSTMVQDGK STGDACGIVI SYSVRIKLNC GTLGGEIQTD VPFKLLQPAP GSVEKKRSNA 370 380 390 400 MKKMKSIEQH RNTKGYYQDD DDNIVFEDFA KMRNNNADVM D

References

[1]	"Mechanism of arrestin 2 function in rhabdomeric photoreceptors." Plangger A., Malicki D., Whitney M., Paulsen R. J. Biol. Chem. 269:26969-26975(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-11. Tissue: Retina.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X79073 mRNA. Translation: CAA55673.1.
PIR	B55081.
3D structure databases
ProteinModelPortal	P51487.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.640. 1 hit. 2.60.40.840. 1 hit.
InterPro	IPR000698. Arrestin. IPR011021. Arrestin-like_N. IPR014752. Arrestin_C. IPR011022. Arrestin_C-like. IPR017864. Arrestin_CS. IPR014753. Arrestin_N. IPR014756. Ig_E-set. [Graphical view]
PANTHER	PTHR11792. PTHR11792. 1 hit.
Pfam	PF02752. Arrestin_C. 1 hit. PF00339. Arrestin_N. 1 hit. [Graphical view]
PRINTS	PR00309. ARRESTIN.
SMART	SM01017. Arrestin_C. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 2 hits.
PROSITE	PS00295. ARRESTINS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARRB_CALVI

Accession

Primary (citable) accession number: P51487

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)