Reviewed, UniProtKB/Swiss-Prot P51271 (HO_PORPU)

Names and origin

Protein names

Recommended name:
    Heme oxygenase
    EC=1.14.99.3

Gene names

Name:

pbsA

Encoded on

Plastid; Chloroplast

Organism

Porphyra purpurea

Taxonomic identifier

2787 [NCBI]

Taxonomic lineage

Eukaryota › Rhodophyta › Bangiophyceae › Bangiales › Bangiaceae › Porphyra

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae By similarity.
Catalytic activity	Heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the heme oxygenase family.

Ontologies

Keywords
Biological process	Photosynthesis
Cellular component	Chloroplast Plastid
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	heme oxidation Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW photosynthesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	heme oxygenase (decyclizing) activity Inferred from electronic annotation. Source: EC iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Heme oxygenase		PRO_0000209699
Sites
	Metal binding	17	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P51271-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 8C512D8C4DA2F0ED	FASTA	236	26,752
	10 20 30 40 50 60 MVSSLANELR EGTTKSHSMA ENVSFVKSFL GGVVDKKSYR KLIANLYFVY SAIEEEILLN 70 80 90 100 110 120 KDHPAIKPIY FTELNRKTSL AKDLNYYYGP DWLNIIEPSS ATQVYVNRIH NIGNKQPELL 130 140 150 160 170 180 VAHAYTRYLG DLSGGQVLKK IARGAMNLSD ERGTKFYDFD EIEDDKIFKN NYRSALDTIP 190 200 210 220 230 LSDEQVQNVV AEANISFTLN MKMFEELNSS IVKIITMIIV STVRKFTLKS ILATAD

References

[1]	"Complete nucleotide sequence of the Porphyra purpurea chloroplast genome." Reith M.E., Munholland J. Plant Mol. Biol. Rep. 13:333-335(1995) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Avonport.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U38804 Genomic DNA. Translation: AAC08157.1.
PIR	S73192.
RefSeq	NP_053881.1.
3D structure databases
HSSP	HSSP built from PDB template 1IRM based on UniProtKB P06762.
ModBase	Search...
Genome annotation databases
GeneID	809900.
Enzyme and pathway databases
BRENDA	1.14.99.3. 279956.
Family and domain databases
InterPro	IPR002051. Haem_Oase. IPR016053. Haem_Oase-like. IPR016084. Haem_Oase-like_multi-hlx. IPR018207. Haem_oxygenase_CS. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
PANTHER	PTHR10720. Haem_Oase. 1 hit.
Pfam	PF01126. Heme_oxygenase. 1 hit. [Graphical view]
PIRSF	PIRSF000343. Haem_Oase. 1 hit.
PRINTS	PR00088. HAEMOXYGNASE.
PROSITE	PS00593. HEME_OXYGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HO_PORPU

Accession

Primary (citable) accession number: P51271

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)