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P51146 (RAB4B_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ras-related protein Rab-4B
Gene names
Name:Rab4b
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Protein transport. Probably involved in vesicular traffic By similarity.

Subcellular location

Cell membrane; Lipid-anchor; Cytoplasmic side Potential.

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 213212Ras-related protein Rab-4B
PRO_0000121101

Regions

Nucleotide binding15 – 239GTP By similarity
Nucleotide binding63 – 675GTP By similarity
Nucleotide binding121 – 1244GTP By similarity
Nucleotide binding151 – 1533GTP By similarity
Motif37 – 459Effector region By similarity

Amino acid modifications

Modified residue21N-acetylalanine By similarity
Modified residue2131Cysteine methyl ester By similarity
Lipidation2111S-geranylgeranyl cysteine By similarity
Lipidation2131S-geranylgeranyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
P51146 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 0C3D76DC328B0018

FASTA21323,629
        10         20         30         40         50         60 
MAETYDFLFK FLVIGSAGTG KSCLLHQFIE NKFKQDSNHT IGVEFGSRVV NVGGKTVKLQ 

        70         80         90        100        110        120 
IWDTAGQERF RSVTRSYYRG AAGALLVYDI TSRETYNSLA AWLTDARTLA SPNIVVILCG 

       130        140        150        160        170        180 
NKKDLDPERE VTFLEASRFA QENELMFLET SALTGENVEE AFLKCARTIL NKIDSGELDP 

       190        200        210 
ERMGSGIQYG DISLRQLRQP RSAQAVAPQP CGC 

« Hide

References

[1]Schuermann A., Muehl-Zuerbes P., Lie C., Joost H.G.
Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Sprague-Dawley.
Tissue: Heart muscle.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X78605 mRNA. Translation: CAA55339.1.
PIRS58279.
RefSeqNP_059051.1. NM_017355.1.
XP_006228645.1. XM_006228583.1.
XP_006228646.1. XM_006228584.1.
UniGeneRn.7181.

3D structure databases

ProteinModelPortalP51146.
SMRP51146. Positions 6-183.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000002052.

Proteomic databases

PaxDbP51146.
PRIDEP51146.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000002052; ENSRNOP00000002052; ENSRNOG00000001500.
GeneID50866.
KEGGrno:50866.
UCSCRGD:620931. rat.

Organism-specific databases

CTD53916.
RGD620931. Rab4b.

Phylogenomic databases

eggNOGCOG1100.
GeneTreeENSGT00710000106651.
HOGENOMHOG000233968.
HOVERGENHBG009351.
InParanoidP51146.
KOK07880.
OMAEAFLKCS.
OrthoDBEOG7QK0CV.
PhylomeDBP51146.
TreeFamTF300032.

Gene expression databases

GenevestigatorP51146.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PRINTSPR00449. RASTRNSFRMNG.
SMARTSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00231. small_GTP. 1 hit.
PROSITEPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio610586.
PROP51146.

Entry information

Entry nameRAB4B_RAT
AccessionPrimary (citable) accession number: P51146
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families