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Protein

Glutamine synthetase cytosolic isozyme 2

Gene

GS1-2

Organism
Vitis vinifera (Grape)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase cytosolic isozyme 2 (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:GS1-2
Synonyms:GS1;2
OrganismiVitis vinifera (Grape)
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Glutamine synthetase cytosolic isozyme 2PRO_0000153200Add
BLAST

Proteomic databases

PRIDEiP51119.

Interactioni

Subunit structurei

Homooctamer.By similarity

Protein-protein interaction databases

STRINGi29760.VIT_14s0006g00350.t01.

Structurei

3D structure databases

ProteinModelPortaliP51119.
SMRiP51119. Positions 4-355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

eggNOGiCOG0174.
HOGENOMiHOG000061500.
KOiK01915.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51119-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLSDLINL NLSDVTEKII AEYIWIGGSG MDLRSKARTL SGPVSDPHKL
60 70 80 90 100
PKWNYDGSST GQAPGEDSEV ILYPQAIFKD PFRRGNNILV MCDTYTPAGE
110 120 130 140 150
PIPTNKRHNA AKIFSHPEVL AEETWYGIEQ EYTLLQNSVK WPIGWPVGGY
160 170 180 190 200
PGPQGPYYCG IGADKAFGRD IVDSHYKACL YAGINISGIN GEVMPGQWEF
210 220 230 240 250
QVGPAVGISA GDELWVARYI LERITEIAGV VVSFDPKPIQ GDWNGAGAHT
260 270 280 290 300
NYSTKSMRND GGYEIIKKAI EKLGLRHKEH IAAYGEGNER RLTGRHETAD
310 320 330 340 350
INTFLWGVAN RGASIRVGRD TEKEGKGYFE DRRPASNMDP YVVTSMIAES

TILWKP
Length:356
Mass (Da):39,322
Last modified:October 1, 1996 - v1
Checksum:i5EB0D289F971E5D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94321 mRNA. Translation: CAA63982.1.
PIRiS71580.
RefSeqiNP_001268054.1. NM_001281125.1.
UniGeneiVvi.13775.

Genome annotation databases

GeneIDi100246404.
KEGGivvi:100246404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94321 mRNA. Translation: CAA63982.1.
PIRiS71580.
RefSeqiNP_001268054.1. NM_001281125.1.
UniGeneiVvi.13775.

3D structure databases

ProteinModelPortaliP51119.
SMRiP51119. Positions 4-355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi29760.VIT_14s0006g00350.t01.

Proteomic databases

PRIDEiP51119.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100246404.
KEGGivvi:100246404.

Phylogenomic databases

eggNOGiCOG0174.
HOGENOMiHOG000061500.
KOiK01915.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization of Vitis vinifera L. glutamine synthetase and molecular cloning of cDNAs for the cytosolic enzyme."
    Loulakakis K.A., Roubelakis-Angelakis K.A.
    Plant Mol. Biol. 31:983-992(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Sultanina.
    Tissue: Shoot.

Entry informationi

Entry nameiGLNA2_VITVI
AccessioniPrimary (citable) accession number: P51119
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 24, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.