SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P51110

- DFRA_VITVI

UniProt

P51110 - DFRA_VITVI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Dihydroflavonol-4-reductase
Gene
DFR
Organism
Vitis vinifera (Grape)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathwayi

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

GO - Biological processi

  1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
  2. cellular metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Flavonoid biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00009.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroflavonol-4-reductase (EC:1.1.1.219)
Short name:
DFR
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene namesi
Name:DFR
OrganismiVitis vinifera (Grape)
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 337337Dihydroflavonol-4-reductase
PRO_0000215572Add
BLAST

Proteomic databases

PRIDEiP51110.

Expressioni

Inductioni

By light.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 126
Helixi16 – 2712
Beta strandi31 – 377
Helixi42 – 498
Helixi54 – 574
Beta strandi58 – 625
Turni68 – 714
Helixi72 – 754
Beta strandi79 – 835
Helixi95 – 984
Helixi100 – 11617
Beta strandi121 – 1266
Helixi129 – 1313
Beta strandi135 – 1373
Beta strandi140 – 1423
Helixi150 – 1567
Helixi161 – 18020
Beta strandi185 – 1906
Beta strandi192 – 1954
Beta strandi198 – 2014
Helixi204 – 2096
Helixi211 – 2144
Helixi217 – 2193
Turni221 – 2244
Beta strandi225 – 2306
Helixi231 – 24313
Beta strandi249 – 2535
Beta strandi256 – 2594
Helixi260 – 27011
Helixi295 – 2995
Helixi308 – 32114

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IODX-ray2.06A/B/C/D1-337[»]
2NNLX-ray2.10D/F1-337[»]
3BXXX-ray2.90A/B/C/D/E/F1-337[»]
3C1TX-ray2.25A/B/C/D1-337[»]
ProteinModelPortaliP51110.
SMRiP51110. Positions 5-330.

Miscellaneous databases

EvolutionaryTraceiP51110.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51110-1 [UniParc]FASTAAdd to Basket

« Hide

MGSQSETVCV TGASGFIGSW LVMRLLERRL TVRATVRDPT NVKKVKHLLD    50
LPKAETHLTL WKADLADEGS FDEAIKGCTG VFHVATPMDF ESKDPENEVI 100
KPTIEGMLGI MKSCAAAKTV RRLVFTSSAG TVNIQEHQLP VYDESCWSDM 150
EFCRAKKMTA WMYFVSKTLA EQAAWKYAKE NNIDFITIIP TLVVGPFIMS 200
SMPPSLITAL SPITGNEAHY SIIRQGQFVH LDDLCNAHIY LFENPKAEGR 250
YICSSHDCII LDLAKMLREK YPEYNIPTEF KGVDENLKSV CFSSKKLTDL 300
GFEFKYSLED MFTGAVDTCR AKGLLRPSHE KPVDGKT 337
Length:337
Mass (Da):37,757
Last modified:October 1, 1996 - v1
Checksum:i73EDB67A03DF94E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X75964 mRNA. Translation: CAA53578.1.
UniGeneiVvi.120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X75964 mRNA. Translation: CAA53578.1 .
UniGenei Vvi.120.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2IOD X-ray 2.06 A/B/C/D 1-337 [» ]
2NNL X-ray 2.10 D/F 1-337 [» ]
3BXX X-ray 2.90 A/B/C/D/E/F 1-337 [» ]
3C1T X-ray 2.25 A/B/C/D 1-337 [» ]
ProteinModelPortali P51110.
SMRi P51110. Positions 5-330.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P51110.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00009 .

Miscellaneous databases

EvolutionaryTracei P51110.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR001509. Epimerase_deHydtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01370. Epimerase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and molecular analysis of structural genes involved in flavonoid and stilbene biosynthesis in grape (Vitis vinifera L.)."
    Sparvoli F., Martin C., Scienza A., Gavazzi G., Tonelli C.
    Plant Mol. Biol. 24:743-755(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Lambrusco Foglia Frastagliata.

Entry informationi

Entry nameiDFRA_VITVI
AccessioniPrimary (citable) accession number: P51110
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi