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P51109 (DFRA_MEDSA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dihydroflavonol-4-reductase

Short name=DFR
EC=1.1.1.219
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene names
Name:DFR1
OrganismMedicago sativa (Alfalfa)
Taxonomic identifier3879 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

Protein attributes

Sequence length217 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathway

Pigment biosynthesis; anthocyanin biosynthesis.

Sequence similarities

Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›217›217Dihydroflavonol-4-reductase
PRO_0000215570

Experimental info

Non-terminal residue11
Non-terminal residue2171

Sequences

Sequence LengthMass (Da)Tools
P51109 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: E8A43AA76CBE3EB2

FASTA21724,389
        10         20         30         40         50         60 
GSWLVMRLME PGYMVRATVR DPENLKKVSP LLELPGAKSK LSIWKADLGE EGSFDEAIKG 

        70         80         90        100        110        120 
CTGVFHVATP MDFESKDPEN EMIKPTIKGV LDIMKACLKA KTVRRLIYTS SAGTLNVTED 

       130        140        150        160        170        180 
QKPLWDESCW SDVEFCRRVK MTGWMYFVSK TLAEQEAWKF AKEHKMDVIT IIPPLVVGPF 

       190        200        210 
LIPTMPPSLI TALSPITGNE AHYSIIKQGQ YVHLDDL 

« Hide

References

[1]"Molecular characterization and expression of alfalfa (Medicago sativa L.) flavanone-3-hydroxylase and dihydroflavonol-4-reductase encoding genes."
Charrier B., Coronado C., Kondorosi A., Ratet P.
Plant Mol. Biol. 29:773-786(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Varia A2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X80222 mRNA. Translation: CAA56508.1.
PIRS61416.

3D structure databases

ProteinModelPortalP51109.
SMRP51109. Positions 1-217.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP51109.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00009.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR001509. Epimerase_deHydtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01370. Epimerase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDFRA_MEDSA
AccessionPrimary (citable) accession number: P51109
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways