Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P51109

- DFRA_MEDSA

UniProt

P51109 - DFRA_MEDSA

Protein

Dihydroflavonol-4-reductase

Gene

DFR1

Organism
Medicago sativa (Alfalfa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

    Pathwayi

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
    2. cellular metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00009.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dihydroflavonol-4-reductase (EC:1.1.1.219)
    Short name:
    DFR
    Alternative name(s):
    Dihydrokaempferol 4-reductase
    Gene namesi
    Name:DFR1
    OrganismiMedicago sativa (Alfalfa)
    Taxonomic identifieri3879 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›217›217Dihydroflavonol-4-reductasePRO_0000215570Add
    BLAST

    Proteomic databases

    PRIDEiP51109.

    Structurei

    3D structure databases

    ProteinModelPortaliP51109.
    SMRiP51109. Positions 1-217.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01370. Epimerase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P51109-1 [UniParc]FASTAAdd to Basket

    « Hide

    GSWLVMRLME PGYMVRATVR DPENLKKVSP LLELPGAKSK LSIWKADLGE    50
    EGSFDEAIKG CTGVFHVATP MDFESKDPEN EMIKPTIKGV LDIMKACLKA 100
    KTVRRLIYTS SAGTLNVTED QKPLWDESCW SDVEFCRRVK MTGWMYFVSK 150
    TLAEQEAWKF AKEHKMDVIT IIPPLVVGPF LIPTMPPSLI TALSPITGNE 200
    AHYSIIKQGQ YVHLDDL 217
    Length:217
    Mass (Da):24,389
    Last modified:October 1, 1996 - v1
    Checksum:iE8A43AA76CBE3EB2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-terminal residuei217 – 2171

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X80222 mRNA. Translation: CAA56508.1.
    PIRiS61416.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X80222 mRNA. Translation: CAA56508.1 .
    PIRi S61416.

    3D structure databases

    ProteinModelPortali P51109.
    SMRi P51109. Positions 1-217.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P51109.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00009 .

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01370. Epimerase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization and expression of alfalfa (Medicago sativa L.) flavanone-3-hydroxylase and dihydroflavonol-4-reductase encoding genes."
      Charrier B., Coronado C., Kondorosi A., Ratet P.
      Plant Mol. Biol. 29:773-786(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Varia A2.

    Entry informationi

    Entry nameiDFRA_MEDSA
    AccessioniPrimary (citable) accession number: P51109
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3