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P51108 (DFRA_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dihydroflavonol-4-reductase

Short name=DFR
EC=1.1.1.219
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene names
Name:A1
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathway

Pigment biosynthesis; anthocyanin biosynthesis.

Sequence similarities

Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357Dihydroflavonol-4-reductase
PRO_0000215569

Sequences

Sequence LengthMass (Da)Tools
P51108 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 6892B51E30E52804

FASTA35738,856
        10         20         30         40         50         60 
MERGAGASEK GTVLVTGASG FVGSWLVMKL LQAGYTVRAT VRDPANVGKT KPLMDLPGAT 

        70         80         90        100        110        120 
ERLSIWKADL AEEGSFHDAI RGCTGVFHVA TPMDFLSKDP ENEVIKPTVE GMISIMRACK 

       130        140        150        160        170        180 
EAGTVRRIVF TSSAGTVNLE ERQRPVYDEE SWTDVDFCRR VKMTGWMYFV SKTLAEKAAL 

       190        200        210        220        230        240 
AYAAEHGLDL VTIIPTLVVG PFISASMPPS LITALALITG NAPHYSILKQ VQLIHLDDLC 

       250        260        270        280        290        300 
DAEIFLFENP AAAGRYVCSS HDVTIHGLAA MLRDRYPEYD VPQRFPGIQD DLQPVRFSSK 

       310        320        330        340        350 
KLQDLGFTFR YKTLEDMFDA AIRTCQEKGL IPLATAAGGD GFASVRAPGE TEATIGA 

« Hide

References

[1]"Influence of transposable elements on the structure and function of the A1 gene of Zea mays."
Schwarz-Sommer Z., Shepherd N., Tacke E., Gierl A., Rohde W., Leclercq L., Mattes M., Berndtgen R., Peterson P.A., Saedler H.
EMBO J. 6:287-294(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Wisconsin 22.
[2]"Endogenous and environmental factors influence 35S promoter methylation of a maize A1 gene construct in transgenic petunia and its colour phenotype."
Meyer P., Linn F., Heidmann I., Heiner Meyer Z.A., Niedenhof I., Saedler H.
Mol. Gen. Genet. 231:345-352(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Wisconsin 22.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X05068 Genomic DNA. Translation: CAA28734.1.
UniGeneZm.95153.

3D structure databases

ProteinModelPortalP51108.
SMRP51108. Positions 12-332.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP51108.
MaizeGDB13795.

Phylogenomic databases

HOGENOMHOG000167998.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-17992.
MetaCyc:MONOMER-17993.
UniPathwayUPA00009.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR013549. DUF1731_C.
IPR001509. Epimerase_deHydtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF08338. DUF1731. 1 hit.
PF01370. Epimerase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDFRA_MAIZE
AccessionPrimary (citable) accession number: P51108
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways