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P51107 (DFRA_SOLLC) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dihydroflavonol-4-reductase

Short name=DFR
EC=1.1.1.219
Alternative name(s):
Dihydrokaempferol 4-reductase
OrganismSolanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome]
Taxonomic identifier4081 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathway

Pigment biosynthesis; anthocyanin biosynthesis.

Tissue specificity

Expressed in both leaf and hypocotyl tissues.

Sequence similarities

Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 379379Dihydroflavonol-4-reductase
PRO_0000215568

Sequences

Sequence LengthMass (Da)Tools
P51107 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 8B23708B01E4A989

FASTA37942,429
        10         20         30         40         50         60 
MASEAHAVVD AHSPPKTTTV WVTGGAGFIG SWLVMRLLER GYNVHATVRD PENQKKVKHL 

        70         80         90        100        110        120 
LELPKADTNL TLWKADLAVE GSFDEAIQGC QGVFHVATPM DFESKDPENE VIKPTVRGML 

       130        140        150        160        170        180 
SIIESCAKAN TVKRLVFTSS AGTLDVQEDQ KLFYDETSWS DLDFIYAKKM TGWMYFVSKI 

       190        200        210        220        230        240 
LAEKAAMEEA RKNNIDFISI IPPLVVGPFI TSTFPPSLIT ALSLITAHYG IIKQGQYVHL 

       250        260        270        280        290        300 
DDLCEAHIFL YEHPKAEGRF ICSSHHAIIY DVAKMVRQKW PEYYVPTEFK GIDKDLALVS 

       310        320        330        340        350        360 
FSSKKLMDIK FQFKHTLEDM YKGAIETCRQ KQLLPFSTRS TADNGKDKEA IPISTENYSS 

       370 
GKENAPVANC TGKFTNGEI 

« Hide

References

[1]"Characterization of the gene encoding dihydroflavonol 4-reductase in tomato."
Bongue-Bartelsman M., O'Neill S.D., Tong Y., Yoder J.I.
Gene 138:153-157(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Hypocotyl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z18277 mRNA. Translation: CAA79154.1.
PIRS38474.
RefSeqNP_001234408.1. NM_001247479.1.
UniGeneLes.3659.

3D structure databases

ProteinModelPortalP51107.
SMRP51107. Positions 19-337.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID544150.
KEGGsly:544150.

Phylogenomic databases

KOK13082.

Enzyme and pathway databases

UniPathwayUPA00009.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR001509. Epimerase_deHydtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01370. Epimerase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDFRA_SOLLC
AccessionPrimary (citable) accession number: P51107
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways