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P51106

- DFRA_HORVU

UniProt

P51106 - DFRA_HORVU

Protein

Dihydroflavonol-4-reductase

Gene

ANT18

Organism
Hordeum vulgare (Barley)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

    Pathwayi

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
    2. cellular metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00009.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dihydroflavonol-4-reductase (EC:1.1.1.219)
    Short name:
    DFR
    Alternative name(s):
    Dihydrokaempferol 4-reductase
    Gene namesi
    Name:ANT18
    OrganismiHordeum vulgare (Barley)
    Taxonomic identifieri4513 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

    Organism-specific databases

    GrameneiP51106.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354Dihydroflavonol-4-reductasePRO_0000215567Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP51106.

    Structurei

    3D structure databases

    ProteinModelPortaliP51106.
    SMRiP51106. Positions 8-326.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01370. Epimerase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P51106-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDGNKGPVVV TGASGFVGSW LVMKLLQAGY TVRATVRDPA NVEKTKPLLE    50
    LPGAKERLSI WKADLSEDGS FNEAIAGCTG VFHVATPMDF DSQDPENEVI 100
    KPTVEGMLSI MRACKEAGTV KRIVFTSSAG SVNIEERPRP AYDQDNWSDI 150
    DYCRRVKMTG WMYFVSKALA EKAAMEYASE NGLDFISIIP TLVVGPFLSA 200
    GMPPSLVTAL ALITGNEAHY SILKQVQLVH LDDLCDAMTF LFEHPEANGR 250
    YICSSHDATI HGLARMLQDR FPEYDIPQKF AGVDDNLQPI HFSSKKLLDH 300
    GFSFRYTTED MFDAAIHTCR DKGLIPLGDV PAPAAGGKLG ALAAGEGQAI 350
    GAET 354
    Length:354
    Mass (Da):38,435
    Last modified:October 1, 1996 - v1
    Checksum:i528524A832815AC9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S69616 Genomic DNA. Translation: AAB20555.1.
    PIRiS18595.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S69616 Genomic DNA. Translation: AAB20555.1 .
    PIRi S18595.

    3D structure databases

    ProteinModelPortali P51106.
    SMRi P51106. Positions 8-326.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei P51106.

    Enzyme and pathway databases

    UniPathwayi UPA00009 .

    Gene expression databases

    Genevestigatori P51106.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01370. Epimerase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structure of the Hordeum vulgare gene encoding dihydroflavonol-4-reductase and molecular analysis of ant18 mutants blocked in flavonoid synthesis."
      Kristiansen K.N., Rohde W.
      Mol. Gen. Genet. 230:49-59(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Gula.

    Entry informationi

    Entry nameiDFRA_HORVU
    AccessioniPrimary (citable) accession number: P51106
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3