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P51106

- DFRA_HORVU

UniProt

P51106 - DFRA_HORVU

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Protein

Dihydroflavonol-4-reductase

Gene

ANT18

Organism
Hordeum vulgare (Barley)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathwayi

GO - Molecular functioni

  1. coenzyme binding Source: EnsemblPlants/Gramene
  2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

GO - Biological processi

  1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
  2. cellular metabolic process Source: EnsemblPlants/Gramene
  3. response to sucrose Source: EnsemblPlants/Gramene
  4. response to UV-B Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Flavonoid biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00009.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroflavonol-4-reductase (EC:1.1.1.219)
Short name:
DFR
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene namesi
Name:ANT18
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Organism-specific databases

GrameneiP51106.

Subcellular locationi

GO - Cellular componenti

  1. extrinsic component of endoplasmic reticulum membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 354354Dihydroflavonol-4-reductasePRO_0000215567Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP51106.

Structurei

3D structure databases

ProteinModelPortaliP51106.
SMRiP51106. Positions 8-326.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51106-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDGNKGPVVV TGASGFVGSW LVMKLLQAGY TVRATVRDPA NVEKTKPLLE
60 70 80 90 100
LPGAKERLSI WKADLSEDGS FNEAIAGCTG VFHVATPMDF DSQDPENEVI
110 120 130 140 150
KPTVEGMLSI MRACKEAGTV KRIVFTSSAG SVNIEERPRP AYDQDNWSDI
160 170 180 190 200
DYCRRVKMTG WMYFVSKALA EKAAMEYASE NGLDFISIIP TLVVGPFLSA
210 220 230 240 250
GMPPSLVTAL ALITGNEAHY SILKQVQLVH LDDLCDAMTF LFEHPEANGR
260 270 280 290 300
YICSSHDATI HGLARMLQDR FPEYDIPQKF AGVDDNLQPI HFSSKKLLDH
310 320 330 340 350
GFSFRYTTED MFDAAIHTCR DKGLIPLGDV PAPAAGGKLG ALAAGEGQAI

GAET
Length:354
Mass (Da):38,435
Last modified:October 1, 1996 - v1
Checksum:i528524A832815AC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S69616 Genomic DNA. Translation: AAB20555.1.
PIRiS18595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S69616 Genomic DNA. Translation: AAB20555.1 .
PIRi S18595.

3D structure databases

ProteinModelPortali P51106.
SMRi P51106. Positions 8-326.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P51106.

Enzyme and pathway databases

UniPathwayi UPA00009 .

Gene expression databases

Genevestigatori P51106.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01370. Epimerase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure of the Hordeum vulgare gene encoding dihydroflavonol-4-reductase and molecular analysis of ant18 mutants blocked in flavonoid synthesis."
    Kristiansen K.N., Rohde W.
    Mol. Gen. Genet. 230:49-59(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Gula.

Entry informationi

Entry nameiDFRA_HORVU
AccessioniPrimary (citable) accession number: P51106
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3