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Protein

Dihydroflavonol-4-reductase

Gene

F

Organism
Callistephus chinensis (China aster) (Callistemma chinense)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathway: anthocyanin biosynthesis

This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.
View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Flavonoid biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

BRENDAi1.1.1.219. 1066.
UniPathwayiUPA00009.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroflavonol-4-reductase (EC:1.1.1.219)
Short name:
DFR
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene namesi
Name:F
OrganismiCallistephus chinensis (China aster) (Callistemma chinense)
Taxonomic identifieri13379 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeAstereaeAustralasian lineagesCallistephus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 364364Dihydroflavonol-4-reductasePRO_0000215564Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP51103.
SMRiP51103. Positions 8-329.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51103-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEDSPPTVC VTGAAGFIGS WLVMRLLERG YIVRATVRNP GDMKKVKHLL
60 70 80 90 100
ELPKAETNLT LWKADLTQEG SFDEAIEGCH GVFHVATPMD FESKDPENEI
110 120 130 140 150
IKPTIEGILS IIRSCAKAKT VKKLVYTSSA GTVNVQETQL PVYDESHWSD
160 170 180 190 200
LDFIYSKKMT AWMYFVSKTL AEKAAMEAAK ENNIDFVSII PPLVVGPFIN
210 220 230 240 250
PTFPPSLITA LSLINGAESH YSIIKQGQYV HLDDLCECHI FLYENPEAKG
260 270 280 290 300
RYICSKQDAT IHQLARMIKQ KWPEYHVPTQ FAGIDEELPT VSFSSKKLID
310 320 330 340 350
MGFKFKYDLE DMFKGAIDSC KEKGFLPYST NEVKKGLFES SINGNVHGQK
360
GNQKIGDEGV KLVN
Length:364
Mass (Da):40,726
Last modified:October 1, 1996 - v1
Checksum:i83E82B02F1AF4329
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67981 mRNA. Translation: CAA91922.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67981 mRNA. Translation: CAA91922.1.

3D structure databases

ProteinModelPortaliP51103.
SMRiP51103. Positions 8-329.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00009.
BRENDAi1.1.1.219. 1066.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Min B., Sommer H., Forkmann G.
    Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: L 01.
    Tissue: Petal.

Entry informationi

Entry nameiDFRA_CALCH
AccessioniPrimary (citable) accession number: P51103
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.