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P51082 (CHSB_PEA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase 1B

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase 1B
Gene names
Name:CHS-1B
OrganismPisum sativum (Garden pea)
Taxonomic identifier3888 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Chalcone synthase 1B
PRO_0000216025

Sites

Active site1641 By similarity

Sequences

Sequence LengthMass (Da)Tools
P51082 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 963105A8C4010C52

FASTA38942,821
        10         20         30         40         50         60 
MVTVDEIRQA QKAEGPATVL AIGTATPPNC VDQSTYPDYY FRITNSEHKT ELKEKFQRMC 

        70         80         90        100        110        120 
DKSMIKKRYM HLTEEILKEN PSVCEYMAPS LDARQDMVVV EVPKLGKEAA TKAIKEWGQP 

       130        140        150        160        170        180 
KSKITHLIFC TTSGVDMPGA DYQLTKLLGL RPHVKRYMMY QQGCFAGGTV LRLAKDLAEN 

       190        200        210        220        230        240 
NKGARVLVVC SEITAVTFRG PSDTHLDSLV GQALFGDGAA AVIVGSDPLP QVEKPLFELV 

       250        260        270        280        290        300 
WTAQTILPDS EGAIDGHLRE VGLTFHLLKD VPGLISKNIE KALVEAFQPL GISDYNSLFW 

       310        320        330        340        350        360 
IAHPGGPAIL DQVEAKLSLK QRKMQATRHV LSEYGNMSSA CVLFILDEMR RKSKEEQLGT 

       370        380 
TGEGLEWGVL FGFGPGLTVE TVVLHSVAT 

« Hide

References

[1]Hellens R.P.
Submitted (JUL-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. JI 813.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X80007 Genomic DNA. Translation: CAA56317.1.
PIRS49203.

3D structure databases

ProteinModelPortalP51082.
SMRP51082. Positions 3-388.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHSB_PEA
AccessionPrimary (citable) accession number: P51082
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways