Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P51053

- SDHB_COXBU

UniProt

P51053 - SDHB_COXBU

Protein

Succinate dehydrogenase iron-sulfur subunit

Gene

sdhB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Succinate + a quinone = fumarate + a quinol.

    Cofactori

    Binds 1 2Fe-2S cluster.
    Binds 1 3Fe-4S cluster.
    Binds 1 4Fe-4S cluster.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi53 – 531Iron-sulfur 1 (2Fe-2S)By similarity
    Metal bindingi58 – 581Iron-sulfur 1 (2Fe-2S)By similarity
    Metal bindingi73 – 731Iron-sulfur 1 (2Fe-2S)By similarity
    Metal bindingi143 – 1431Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi146 – 1461Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi149 – 1491Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi153 – 1531Iron-sulfur 3 (3Fe-4S)By similarity
    Binding sitei158 – 1581Ubiquinone; shared with SdhD subunitBy similarity
    Metal bindingi200 – 2001Iron-sulfur 3 (3Fe-4S)By similarity
    Metal bindingi206 – 2061Iron-sulfur 3 (3Fe-4S)By similarity
    Metal bindingi210 – 2101Iron-sulfur 2 (4Fe-4S)By similarity

    GO - Molecular functioni

    1. 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
    2. 3 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    3. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    4. electron carrier activity Source: InterPro
    5. metal ion binding Source: UniProtKB-KW
    6. succinate dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

    GO - Biological processi

    1. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Transport, Tricarboxylic acid cycle

    Keywords - Ligandi

    2Fe-2S, 3Fe-4S, 4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Enzyme and pathway databases

    BioCyciCBUR227377:GJ7S-1388-MONOMER.
    UniPathwayiUPA00223; UER01005.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinate dehydrogenase iron-sulfur subunit (EC:1.3.5.1)
    Gene namesi
    Name:sdhB
    Ordered Locus Names:CBU_1400
    OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
    Taxonomic identifieri227377 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
    ProteomesiUP000002671: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 235235Succinate dehydrogenase iron-sulfur subunitPRO_0000158687Add
    BLAST

    Proteomic databases

    PRIDEiP51053.

    Interactioni

    Subunit structurei

    Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, cytochrome b-556 and a hydrophobic protein.

    Protein-protein interaction databases

    STRINGi227377.CBU_1400.

    Structurei

    3D structure databases

    ProteinModelPortaliP51053.
    SMRiP51053. Positions 1-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini133 – 163314Fe-4S ferredoxin-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 4Fe-4S ferredoxin-type domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0479.
    HOGENOMiHOG000160590.
    KOiK00240.
    OMAiQYEKIRP.
    OrthoDBiEOG6CK7MG.

    Family and domain databases

    Gene3Di3.10.20.30. 1 hit.
    InterProiIPR001041. 2Fe-2S_ferredoxin-type.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR012675. Beta-grasp_dom.
    IPR009051. Helical_ferredxn.
    IPR004489. Succ_DH/fum_Rdtase_Fe-S.
    IPR025192. Succ_DH/fum_Rdtase_N.
    [Graphical view]
    PfamiPF13085. Fer2_3. 1 hit.
    PF13183. Fer4_8. 1 hit.
    [Graphical view]
    SUPFAMiSSF46548. SSF46548. 1 hit.
    SSF54292. SSF54292. 1 hit.
    TIGRFAMsiTIGR00384. dhsB. 1 hit.
    PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P51053-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTFSIMRFNP ETDKKPYMQD FELDVSAIQG KMLLNALEAL REKHPDIGLR    50
    RSCAEGVCGS DGMNINGKNA LACVTQLKDL PDRVVVRPLP GFPIIRDLIV 100
    DMEQFYAQYK KVKPYLLNDQ EAPQKERLQS PEERAKLDGL YECILCACCS 150
    SSCPSYWWNP DKFIGPAGLL WSYRFIADSR DSKEKERLDA MKDPYSVFRC 200
    RTIMDCATVC PKNLNPAKAI RKIRTEMLQE TESGE 235
    Length:235
    Mass (Da):26,847
    Last modified:October 1, 1996 - v1
    Checksum:i5949664A63BF5B41
    GO

    Sequence cautioni

    The sequence AAO90899.1 differs from that shown. Reason: Erroneous initiation.
    The sequence CAA54873.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L33409 Genomic DNA. Translation: AAA74134.1.
    X77919 Genomic DNA. Translation: CAA54873.1. Different initiation.
    AE016828 Genomic DNA. Translation: AAO90899.1. Different initiation.
    PIRiS42873.
    RefSeqiNP_820385.1. NC_002971.3.

    Genome annotation databases

    EnsemblBacteriaiAAO90899; AAO90899; CBU_1400.
    GeneIDi1209306.
    KEGGicbu:CBU_1400.
    PATRICi17931557. VBICoxBur82552_1402.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L33409 Genomic DNA. Translation: AAA74134.1 .
    X77919 Genomic DNA. Translation: CAA54873.1 . Different initiation.
    AE016828 Genomic DNA. Translation: AAO90899.1 . Different initiation.
    PIRi S42873.
    RefSeqi NP_820385.1. NC_002971.3.

    3D structure databases

    ProteinModelPortali P51053.
    SMRi P51053. Positions 1-229.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227377.CBU_1400.

    Proteomic databases

    PRIDEi P51053.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO90899 ; AAO90899 ; CBU_1400 .
    GeneIDi 1209306.
    KEGGi cbu:CBU_1400.
    PATRICi 17931557. VBICoxBur82552_1402.

    Phylogenomic databases

    eggNOGi COG0479.
    HOGENOMi HOG000160590.
    KOi K00240.
    OMAi QYEKIRP.
    OrthoDBi EOG6CK7MG.

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER01005 .
    BioCyci CBUR227377:GJ7S-1388-MONOMER.

    Family and domain databases

    Gene3Di 3.10.20.30. 1 hit.
    InterProi IPR001041. 2Fe-2S_ferredoxin-type.
    IPR017896. 4Fe4S_Fe-S-bd.
    IPR017900. 4Fe4S_Fe_S_CS.
    IPR012675. Beta-grasp_dom.
    IPR009051. Helical_ferredxn.
    IPR004489. Succ_DH/fum_Rdtase_Fe-S.
    IPR025192. Succ_DH/fum_Rdtase_N.
    [Graphical view ]
    Pfami PF13085. Fer2_3. 1 hit.
    PF13183. Fer4_8. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46548. SSF46548. 1 hit.
    SSF54292. SSF54292. 1 hit.
    TIGRFAMsi TIGR00384. dhsB. 1 hit.
    PROSITEi PS00198. 4FE4S_FER_1. 1 hit.
    PS51379. 4FE4S_FER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the succinate dehydrogenase-encoding gene cluster (sdh) from the rickettsia Coxiella burnetii."
      Heinzen R.A., Mo Y.-Y., Robertson S.J., Mallavia L.P.
      Gene 155:27-34(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Nine Mile.
    2. Thiele D., Willems H., Oswald W., Krauss H.
      Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Nine Mile.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RSA 493 / Nine Mile phase I.

    Entry informationi

    Entry nameiSDHB_COXBU
    AccessioniPrimary (citable) accession number: P51053
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Coxiella burnetii
      Coxiella burnetii (strain RSA 493): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3