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P51041

- CISY_RICCA

UniProt

P51041 - CISY_RICCA

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Protein
Citrate synthase
Gene
gltA
Organism
Rickettsia canadensis
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei304 – 3041 By similarity
Active sitei363 – 3631 By similarity

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase (EC:2.3.3.16)
Gene namesi
Name:gltA
OrganismiRickettsia canadensis
Taxonomic identifieri788 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›411›411Citrate synthase
PRO_0000169960Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP51041.
SMRiP51041. Positions 15-411.

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P51041-1 [UniParc]FASTAAdd to Basket

« Hide

DSEFVELKIR GKIFKLPILK ASIGEDVIDI SRVSSEADCF TYDPGFMSTA    50
SCRSTITYID GDKGILRYRG YDIKDLADKS DFLEVAYLLI YGELPSSEQY 100
NNFTKKVAVH SLVNERLHYL FQTFCSSSHP MAIMLAAVGS LSAFYPDLLN 150
FKEADYELTA IRMIAKIPTM AAMSYKYSIG QPFIYPDNSL DFTENFLHMM 200
FATPCMKYEV NPVIKNALNK IFILHADHEQ NASTSTVRIA GSSGANPFAC 250
ISTGIASLWG PAHGGANEAV INMLKEIGSS ENIPKYIAKA KDKDDPFRLM 300
GFGHRVYKNY DPRAAVLKET CNEVLKELGQ LENNPLLQIA IELEAIALKD 350
EYFIERKLYP NVDFYSGIIY KAMGIPSQMF TVLFAIARTV GWMAQWKEMH 400
EDPEQKISRP R 411
Length:411
Mass (Da):46,298
Last modified:November 1, 1997 - v2
Checksum:i8596D3806FBE78E3
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei411 – 4111

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U59713 Genomic DNA. Translation: AAB02957.1.
U20241 Genomic DNA. Translation: AAA85706.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U59713 Genomic DNA. Translation: AAB02957.1 .
U20241 Genomic DNA. Translation: AAA85706.1 .

3D structure databases

ProteinModelPortali P51041.
SMRi P51041. Positions 15-411.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .

Family and domain databases

Gene3Di 1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001369. Citrate_synth. 1 hit.
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Citrate synthase gene comparison, a new tool for phylogenetic analysis, and its application for the rickettsiae."
    Roux V., Rydkina E., Eremeeva M., Raoult D.
    Int. J. Syst. Bacteriol. 47:252-261(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 2678.
  2. Balayeva N., Eremeeva M., Tissot-Dupont H., Zakharov I., Raoult D.
    Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 264-382.
    Strain: 2678.

Entry informationi

Entry nameiCISY_RICCA
AccessioniPrimary (citable) accession number: P51041
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 1, 1997
Last modified: September 3, 2014
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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