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P51038 (CISY2_RHITR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Citrate synthase, plasmid

EC=2.3.3.16
Gene names
Name:pcsA
Encoded onPlasmid sym
OrganismRhizobium tropici
Taxonomic identifier398 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The exact function of the plasmid-encoded citrate synthase is not clear, it could help nodulation by allowing the bacteria to use citrate as a chelator of iron and calcium.

Catalytic activity

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.

Sequence similarities

Belongs to the citrate synthase family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   Molecular functionTransferase
   Technical termPlasmid
Gene Ontology (GO)
   Biological_processcellular carbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncitrate (Si)-synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 429429Citrate synthase, plasmid
PRO_0000169955

Sites

Active site3061 By similarity
Active site3641 By similarity

Sequences

Sequence LengthMass (Da)Tools
P51038 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: C2E4560E4FE03485

FASTA42948,105
        10         20         30         40         50         60 
MDNNNACVLV DGHSAELKLR SSTIGPNVLG IGSLYEQTKM FTYDPGFTST ASCESSITFI 

        70         80         90        100        110        120 
DGDEGVLLHR GYPIEQLAEH GDFLEVCYLL LYGELPTAAQ KKDFDYRVVH HTMVHEQMSR 

       130        140        150        160        170        180 
FFTGFRRDAH PMAVMCGCVG ALSAFYHDST DITDPHQRMV ASLRMIAKMP TLAAMAYKYH 

       190        200        210        220        230        240 
IGQPFVYPKN DLDYASNFLR MCFAVPCEEY VVNPVLARAM DRIFILHADH EQNASTSTVR 

       250        260        270        280        290        300 
LAGSSGANPF ACIAAGIACL WGPAHGGANE RALNMLTEIG TVDRIPEYIA RAKDKNDPFR 

       310        320        330        340        350        360 
LMGFGHRVYK NYDPRAKIMQ KTAHEVLGEL GIKDDPLLDI AIELERIALT DDYFIEKKLY 

       370        380        390        400        410        420 
PNVDFYSGIT LKALGFPTTM FTVLFALART VGWIAQWNEM IEDPDQRIGR PRQLYTGAPL 


REYVPLSKR 

« Hide

References

[1]"Nodulating ability of Rhizobium tropici is conditioned by a plasmid-encoded citrate synthase."
Pardo M.A., Lagunez J., Miranda J., Martinez E.
Mol. Microbiol. 11:315-321(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CFN 299.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z34516 Genomic DNA. Translation: CAA84274.1.
PIRS41527.

3D structure databases

ProteinModelPortalP51038.
SMRP51038. Positions 4-429.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP51038.
ProMEXP51038.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00223; UER00717.

Family and domain databases

Gene3D1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-II.
[Graphical view]
PANTHERPTHR11739. PTHR11739. 1 hit.
PfamPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001369. Citrate_synth. 1 hit.
PRINTSPR00143. CITRTSNTHASE.
SUPFAMSSF48256. SSF48256. 1 hit.
TIGRFAMsTIGR01798. cit_synth_I. 1 hit.
PROSITEPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCISY2_RHITR
AccessionPrimary (citable) accession number: P51038
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways