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P51034

- CISY_BARQU

UniProt

P51034 - CISY_BARQU

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Protein
Citrate synthase
Gene
gltA, BQ06850
Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei306 – 3061 By similarity
Active sitei364 – 3641 By similarity

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

BioCyciBQUI283165:GHZA-684-MONOMER.
UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase (EC:2.3.3.16)
Gene namesi
Name:gltA
Ordered Locus Names:BQ06850
OrganismiBartonella quintana (strain Toulouse) (Rochalimaea quintana)
Taxonomic identifieri283165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000597: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 438438Citrate synthase
PRO_0000169935Add
BLAST

Proteomic databases

PRIDEiP51034.

Interactioni

Protein-protein interaction databases

STRINGi283165.BQ06850.

Structurei

3D structure databases

ProteinModelPortaliP51034.
SMRiP51034. Positions 2-429.

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.

Phylogenomic databases

eggNOGiCOG0372.
HOGENOMiHOG000021224.
KOiK01647.
OMAiKETCDEV.
OrthoDBiEOG6P8TP4.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51034-1 [UniParc]FASTAAdd to Basket

« Hide

MSENKAHITV NNKKIELSVR KGTLGPGVIE IASLYKETDT FTYDPGFTST    50
ASCESKITYI DGDKGILLYC GYPIDQLAEK GDFLESCYLL LYGELPTKQE 100
KIDFDRCIMQ HMMVHEQFTR FFHGFRRDSH PMAVMVACLG AMSAFYHDSI 150
DIKDAQQRMI AAIRLISKVP TLAAMAYKYS IGQAFVYPRN DLSYAANFLH 200
MCFSVPCEEY KINPVLSRAM DRIFTLHADH EQNASTSTVR LVGSSGANPF 250
ACIAAGVACL WGPAHGGANE ACLKMLQKIG SVERIPEFIA RAKDKNDPFR 300
LMGFGHRVYK NYDPRAKIMQ QTCHEVLKEL NIQDDPLLDI AIALENTALN 350
DEYFIEKKLY PNVDFYSGIT LKALGFPTEM FTVLFALARS IGWVAQWKEM 400
IEDPAQKIGR PRQLYTGYAA REYVSIDKRI SKNKMTTQ 438
Length:438
Mass (Da):49,464
Last modified:August 16, 2004 - v3
Checksum:i98ED2C4A41ACD5E4
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti117 – 1171Q → R in CAA93836. 1 Publication
Sequence conflicti224 – 2241F → C in CAA93836. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26174.1.
Z70014 Genomic DNA. Translation: CAA93836.1.
U28073 Genomic DNA. Translation: AAA74978.1.
RefSeqiWP_011179429.1. NC_005955.1.
YP_032322.1. NC_005955.1.

Genome annotation databases

EnsemblBacteriaiCAF26174; CAF26174; BQ06850.
GeneIDi2867054.
KEGGibqu:BQ06850.
PATRICi31952667. VBIBarQui58630_0759.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26174.1 .
Z70014 Genomic DNA. Translation: CAA93836.1 .
U28073 Genomic DNA. Translation: AAA74978.1 .
RefSeqi WP_011179429.1. NC_005955.1.
YP_032322.1. NC_005955.1.

3D structure databases

ProteinModelPortali P51034.
SMRi P51034. Positions 2-429.
ModBasei Search...

Protein-protein interaction databases

STRINGi 283165.BQ06850.

Proteomic databases

PRIDEi P51034.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF26174 ; CAF26174 ; BQ06850 .
GeneIDi 2867054.
KEGGi bqu:BQ06850.
PATRICi 31952667. VBIBarQui58630_0759.

Phylogenomic databases

eggNOGi COG0372.
HOGENOMi HOG000021224.
KOi K01647.
OMAi KETCDEV.
OrthoDBi EOG6P8TP4.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .
BioCyci BQUI283165:GHZA-684-MONOMER.

Family and domain databases

Gene3Di 1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001369. Citrate_synth. 1 hit.
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Toulouse.
  2. "Comparison of partial citrate synthase gene (gltA) sequences for phylogenetic analysis of Bartonella species."
    Birtles R.J., Raoult D.
    Int. J. Syst. Bacteriol. 46:891-897(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 60-379.
    Strain: ATCC VR-358 / Fuller / CIP 107027.
  3. "Bartonella species characterization: citrate synthase (gltA) PCR product sequence analysis."
    Jones D.C., Regnery R., Bowen M.
    Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 268-379.
    Strain: ATCC VR-358 / Fuller / CIP 107027.

Entry informationi

Entry nameiCISY_BARQU
AccessioniPrimary (citable) accession number: P51034
Secondary accession number(s): Q6FZN8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: August 16, 2004
Last modified: September 3, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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