Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P51034

- CISY_BARQU

UniProt

P51034 - CISY_BARQU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Citrate synthase

Gene

gltA

Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei306 – 3061PROSITE-ProRule annotation
Active sitei364 – 3641PROSITE-ProRule annotation

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

BioCyciBQUI283165:GHZA-684-MONOMER.
UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase (EC:2.3.3.16)
Gene namesi
Name:gltA
Ordered Locus Names:BQ06850
OrganismiBartonella quintana (strain Toulouse) (Rochalimaea quintana)
Taxonomic identifieri283165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000597: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 438438Citrate synthasePRO_0000169935Add
BLAST

Proteomic databases

PRIDEiP51034.

Interactioni

Protein-protein interaction databases

STRINGi283165.BQ06850.

Structurei

3D structure databases

ProteinModelPortaliP51034.
SMRiP51034. Positions 2-429.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.Curated

Phylogenomic databases

eggNOGiCOG0372.
HOGENOMiHOG000021224.
KOiK01647.
OMAiKETCDEV.
OrthoDBiEOG6P8TP4.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51034-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSENKAHITV NNKKIELSVR KGTLGPGVIE IASLYKETDT FTYDPGFTST
60 70 80 90 100
ASCESKITYI DGDKGILLYC GYPIDQLAEK GDFLESCYLL LYGELPTKQE
110 120 130 140 150
KIDFDRCIMQ HMMVHEQFTR FFHGFRRDSH PMAVMVACLG AMSAFYHDSI
160 170 180 190 200
DIKDAQQRMI AAIRLISKVP TLAAMAYKYS IGQAFVYPRN DLSYAANFLH
210 220 230 240 250
MCFSVPCEEY KINPVLSRAM DRIFTLHADH EQNASTSTVR LVGSSGANPF
260 270 280 290 300
ACIAAGVACL WGPAHGGANE ACLKMLQKIG SVERIPEFIA RAKDKNDPFR
310 320 330 340 350
LMGFGHRVYK NYDPRAKIMQ QTCHEVLKEL NIQDDPLLDI AIALENTALN
360 370 380 390 400
DEYFIEKKLY PNVDFYSGIT LKALGFPTEM FTVLFALARS IGWVAQWKEM
410 420 430
IEDPAQKIGR PRQLYTGYAA REYVSIDKRI SKNKMTTQ
Length:438
Mass (Da):49,464
Last modified:August 16, 2004 - v3
Checksum:i98ED2C4A41ACD5E4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti117 – 1171Q → R in CAA93836. (PubMed:8863415)Curated
Sequence conflicti224 – 2241F → C in CAA93836. (PubMed:8863415)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897700 Genomic DNA. Translation: CAF26174.1.
Z70014 Genomic DNA. Translation: CAA93836.1.
U28073 Genomic DNA. Translation: AAA74978.1.
RefSeqiWP_011179429.1. NC_005955.1.
YP_032322.1. NC_005955.1.

Genome annotation databases

EnsemblBacteriaiCAF26174; CAF26174; BQ06850.
GeneIDi2867054.
KEGGibqu:BQ06850.
PATRICi31952667. VBIBarQui58630_0759.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897700 Genomic DNA. Translation: CAF26174.1 .
Z70014 Genomic DNA. Translation: CAA93836.1 .
U28073 Genomic DNA. Translation: AAA74978.1 .
RefSeqi WP_011179429.1. NC_005955.1.
YP_032322.1. NC_005955.1.

3D structure databases

ProteinModelPortali P51034.
SMRi P51034. Positions 2-429.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 283165.BQ06850.

Proteomic databases

PRIDEi P51034.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF26174 ; CAF26174 ; BQ06850 .
GeneIDi 2867054.
KEGGi bqu:BQ06850.
PATRICi 31952667. VBIBarQui58630_0759.

Phylogenomic databases

eggNOGi COG0372.
HOGENOMi HOG000021224.
KOi K01647.
OMAi KETCDEV.
OrthoDBi EOG6P8TP4.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .
BioCyci BQUI283165:GHZA-684-MONOMER.

Family and domain databases

Gene3Di 1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001369. Citrate_synth. 1 hit.
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Toulouse.
  2. "Comparison of partial citrate synthase gene (gltA) sequences for phylogenetic analysis of Bartonella species."
    Birtles R.J., Raoult D.
    Int. J. Syst. Bacteriol. 46:891-897(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 60-379.
    Strain: ATCC VR-358 / Fuller / CIP 107027.
  3. "Bartonella species characterization: citrate synthase (gltA) PCR product sequence analysis."
    Jones D.C., Regnery R., Bowen M.
    Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 268-379.
    Strain: ATCC VR-358 / Fuller / CIP 107027.

Entry informationi

Entry nameiCISY_BARQU
AccessioniPrimary (citable) accession number: P51034
Secondary accession number(s): Q6FZN8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: August 16, 2004
Last modified: November 26, 2014
This is version 88 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3