ID   FNRL_CERS4              Reviewed;         248 AA.
AC   P51007; Q3J010;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   RecName: Full=Transcriptional activator protein FnrL;
GN   Name=fnrL; OrderedLocusNames=RHOS4_23060; ORFNames=RSP_0698;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7592416; DOI=10.1128/jb.177.22.6422-6431.1995;
RA   Zeilstra-Ryalls J.H., Kaplan S.;
RT   "Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the
RT   role of the fnrL gene.";
RL   J. Bacteriol. 177:6422-6431(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC
RC   12203 / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Anaerobic regulatory protein; transcriptional activator of
CC       hemA. Appears to regulate other genes.
CC   -!- MISCELLANEOUS: Possesses 4 cysteines which may bind a metal ion
CC       (possibly iron).
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DR   EMBL; Z49746; CAA89820.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA79874.1; -; Genomic_DNA.
DR   RefSeq; WP_002720880.1; NZ_CP030271.1.
DR   RefSeq; YP_353775.1; NC_007493.2.
DR   AlphaFoldDB; P51007; -.
DR   SMR; P51007; -.
DR   STRING; 272943.RSP_0698; -.
DR   EnsemblBacteria; ABA79874; ABA79874; RSP_0698.
DR   KEGG; rsp:RSP_0698; -.
DR   PATRIC; fig|272943.9.peg.2650; -.
DR   eggNOG; COG0664; Bacteria.
DR   OrthoDB; 667966at2; -.
DR   PhylomeDB; P51007; -.
DR   Proteomes; UP000002703; Chromosome 1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   CDD; cd00092; HTH_CRP; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   PANTHER; PTHR24567:SF75; FUMARATE AND NITRATE REDUCTION REGULATORY PROTEIN; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   PRINTS; PR00034; HTHCRP.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS00042; HTH_CRP_1; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Iron; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..248
FT                   /note="Transcriptional activator protein FnrL"
FT                   /id="PRO_0000100180"
FT   DOMAIN          154..232
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
FT   DNA_BIND        191..210
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
SQ   SEQUENCE   248 AA;  27800 MW;  788F5BB365AE7DAD CRC64;
     MTLHEVPTIL HRCGDCPIRH RAVCARCDSE ELATLEQIKY YRSYQAGQTV IWSGDKMDFV
     ASVVTGIATL TQTMEDGRRQ MVGLLLPSDF VGRPGRQTVA YDVTATTDLL MCCFRRKPFE
     EMMQKTPHVG QRLLEMTLDE LDAAREWMLL LGRKTAREKI ASLLAIIARR DAALKLRESN
     GPMTFDLPLT REEMADYLGL TLETVSRQVS ALKRDGVIAL EGKRHVIVTD FARLLEEAGD
     DSDGGLPV
//