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P51007 (FNRL_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcriptional activator protein FnrL
Gene names
Name:fnrL
Ordered Locus Names:RHOS4_23060
ORF Names:RSP_0698
OrganismRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Reference proteome] [HAMAP]
Taxonomic identifier272943 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length248 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes.

Miscellaneous

Possesses 4 cysteines which may bind a metal ion (possibly iron).

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   LigandDNA-binding
Iron
   Molecular functionActivator
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 248248Transcriptional activator protein FnrL
PRO_0000100180

Regions

Domain154 – 23279HTH crp-type
DNA binding191 – 21020H-T-H motif Potential

Sequences

Sequence LengthMass (Da)Tools
P51007 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 788F5BB365AE7DAD

FASTA24827,800
        10         20         30         40         50         60 
MTLHEVPTIL HRCGDCPIRH RAVCARCDSE ELATLEQIKY YRSYQAGQTV IWSGDKMDFV 

        70         80         90        100        110        120 
ASVVTGIATL TQTMEDGRRQ MVGLLLPSDF VGRPGRQTVA YDVTATTDLL MCCFRRKPFE 

       130        140        150        160        170        180 
EMMQKTPHVG QRLLEMTLDE LDAAREWMLL LGRKTAREKI ASLLAIIARR DAALKLRESN 

       190        200        210        220        230        240 
GPMTFDLPLT REEMADYLGL TLETVSRQVS ALKRDGVIAL EGKRHVIVTD FARLLEEAGD 


DSDGGLPV 

« Hide

References

« Hide 'large scale' references
[1]"Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the role of the fnrL gene."
Zeilstra-Ryalls J.H., Kaplan S.
J. Bacteriol. 177:6422-6431(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49746 Genomic DNA. Translation: CAA89820.1.
CP000143 Genomic DNA. Translation: ABA79874.1.
RefSeqYP_353775.1. NC_007493.2.

3D structure databases

ProteinModelPortalP51007.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272943.RSP_0698.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA79874; ABA79874; RSP_0698.
GeneID3718176.
KEGGrsp:RSP_0698.
PATRIC23154559. VBIRhoSph57909_2650.

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000186462.
KOK01420.
OMACDADELE.
OrthoDBEOG6TBHH3.
PhylomeDBP51007.

Enzyme and pathway databases

BioCycRSPH272943:GJAS-2364-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFNRL_RHOS4
AccessionPrimary (citable) accession number: P51007
Secondary accession number(s): Q3J010
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families