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P51007

- FNRL_RHOS4

UniProt

P51007 - FNRL_RHOS4

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Protein

Transcriptional activator protein FnrL

Gene
fnrL, RHOS4_23060, RSP_0698
Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi191 – 21020H-T-H motif Reviewed predictionAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Iron

Enzyme and pathway databases

BioCyciRSPH272943:GJAS-2364-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator protein FnrL
Gene namesi
Name:fnrL
Ordered Locus Names:RHOS4_23060
ORF Names:RSP_0698
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000002703: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 248248Transcriptional activator protein FnrLPRO_0000100180Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272943.RSP_0698.

Structurei

3D structure databases

ProteinModelPortaliP51007.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini154 – 23279HTH crp-typeAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0664.
HOGENOMiHOG000186462.
KOiK01420.
OMAiCDADELE.
OrthoDBiEOG6TBHH3.
PhylomeDBiP51007.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
SMARTiSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P51007-1 [UniParc]FASTAAdd to Basket

« Hide

MTLHEVPTIL HRCGDCPIRH RAVCARCDSE ELATLEQIKY YRSYQAGQTV    50
IWSGDKMDFV ASVVTGIATL TQTMEDGRRQ MVGLLLPSDF VGRPGRQTVA 100
YDVTATTDLL MCCFRRKPFE EMMQKTPHVG QRLLEMTLDE LDAAREWMLL 150
LGRKTAREKI ASLLAIIARR DAALKLRESN GPMTFDLPLT REEMADYLGL 200
TLETVSRQVS ALKRDGVIAL EGKRHVIVTD FARLLEEAGD DSDGGLPV 248
Length:248
Mass (Da):27,800
Last modified:October 1, 1996 - v1
Checksum:i788F5BB365AE7DAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49746 Genomic DNA. Translation: CAA89820.1.
CP000143 Genomic DNA. Translation: ABA79874.1.
RefSeqiWP_002720880.1. NZ_AKVW01000001.1.
YP_353775.1. NC_007493.2.

Genome annotation databases

EnsemblBacteriaiABA79874; ABA79874; RSP_0698.
GeneIDi3718176.
KEGGirsp:RSP_0698.
PATRICi23154559. VBIRhoSph57909_2650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49746 Genomic DNA. Translation: CAA89820.1 .
CP000143 Genomic DNA. Translation: ABA79874.1 .
RefSeqi WP_002720880.1. NZ_AKVW01000001.1.
YP_353775.1. NC_007493.2.

3D structure databases

ProteinModelPortali P51007.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272943.RSP_0698.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA79874 ; ABA79874 ; RSP_0698 .
GeneIDi 3718176.
KEGGi rsp:RSP_0698.
PATRICi 23154559. VBIRhoSph57909_2650.

Phylogenomic databases

eggNOGi COG0664.
HOGENOMi HOG000186462.
KOi K01420.
OMAi CDADELE.
OrthoDBi EOG6TBHH3.
PhylomeDBi P51007.

Enzyme and pathway databases

BioCyci RSPH272943:GJAS-2364-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProi IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00027. cNMP_binding. 1 hit.
[Graphical view ]
PRINTSi PR00034. HTHCRP.
SMARTi SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view ]
SUPFAMi SSF51206. SSF51206. 1 hit.
PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the role of the fnrL gene."
    Zeilstra-Ryalls J.H., Kaplan S.
    J. Bacteriol. 177:6422-6431(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Entry informationi

Entry nameiFNRL_RHOS4
AccessioniPrimary (citable) accession number: P51007
Secondary accession number(s): Q3J010
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Possesses 4 cysteines which may bind a metal ion (possibly iron).

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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