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Protein

60S ribosomal protein L18

Gene

RPL18-A

more
Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L18
Gene namesi
Name:RPL18-A
ORF Names:Tb10.6k15.0410
AND
Name:RPL18-B
ORF Names:Tb11.02.1840
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
ProteomesiUP000008524: Chromosome 10, UP000008524: Chromosome 11 Scaffold 1

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 19319360S ribosomal protein L18PRO_0000132779Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5691.Tb11.02.1840.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V8Melectron microscopy5.57BI1-193[»]
ProteinModelPortaliP50885.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L18e family.Curated

Phylogenomic databases

eggNOGiCOG1727.
HOGENOMiHOG000213425.
InParanoidiP50885.
KOiK02883.
OMAiFMEGKGD.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
IPR021132. Ribosomal_L18e_CS.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS01106. RIBOSOMAL_L18E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50885-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVDLTGVQK KKRVVRHHTY STNPYIKLLI KLYKFLGKRT NSPFNKLIHK
60 70 80 90 100
RLLKSRNNRA PISLSRIAVC MRRRTVWLKK GKKSPIAVIV GDVLDDVRMT
110 120 130 140 150
RIPALRICAL RFSKSARERI TGAGGECLTF DQLAMMAPTG KNTMLLRGRK
160 170 180 190
SGRESVKHFG AAGVPGSHAK PHVSSRGKER QRSSKRRHAF RHK
Length:193
Mass (Da):21,874
Last modified:October 1, 1996 - v1
Checksum:i350856090EAD0388
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47286 mRNA. Translation: AAC47428.1.
CM000208 Genomic DNA. Translation: EAN78382.1.
CH464491 Genomic DNA. Translation: EAN79394.1.
RefSeqiXP_823210.1. XM_818117.1.
XP_828506.1. XM_823413.1.

Genome annotation databases

GeneIDi3661727.
3664868.
KEGGitbr:Tb10.6k15.0410.
tbr:Tb11.02.1840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U47286 mRNA. Translation: AAC47428.1.
CM000208 Genomic DNA. Translation: EAN78382.1.
CH464491 Genomic DNA. Translation: EAN79394.1.
RefSeqiXP_823210.1. XM_818117.1.
XP_828506.1. XM_823413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V8Melectron microscopy5.57BI1-193[»]
ProteinModelPortaliP50885.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5691.Tb11.02.1840.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3661727.
3664868.
KEGGitbr:Tb10.6k15.0410.
tbr:Tb11.02.1840.

Phylogenomic databases

eggNOGiCOG1727.
HOGENOMiHOG000213425.
InParanoidiP50885.
KOiK02883.
OMAiFMEGKGD.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
IPR021132. Ribosomal_L18e_CS.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS01106. RIBOSOMAL_L18E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The cloning and sequencing of a ribosomal L18 protein from an evolutionary divergent eukaryote, Trypanosoma brucei."
    Coulter L.J., Hide G.
    Biochim. Biophys. Acta 1309:69-72(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.

Entry informationi

Entry nameiRL18_TRYB2
AccessioniPrimary (citable) accession number: P50885
Secondary accession number(s): Q385Y7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 4, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.