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Protein

60S ribosomal protein L3

Gene

rpl-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L3
Gene namesi
Name:rpl-3
ORF Names:F13B10.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF13B10.2a ; CE05598 ; WBGene00004414 ; rpl-3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000772351 – 40160S ribosomal protein L3Add BLAST401

Proteomic databases

EPDiP50880
PaxDbiP50880
PeptideAtlasiP50880
PRIDEiP50880

Expressioni

Gene expression databases

BgeeiWBGene00004414
ExpressionAtlasiP50880 baseline

Interactioni

Protein-protein interaction databases

BioGridi40739, 13 interactors
DIPiDIP-24912N
IntActiP50880, 10 interactors
STRINGi6239.F13B10.2a.1

Structurei

3D structure databases

ProteinModelPortaliP50880
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0746 Eukaryota
COG0087 LUCA
GeneTreeiENSGT00390000017606
HOGENOMiHOG000107319
InParanoidiP50880
KOiK02925
OMAiHQRTEYN
OrthoDBiEOG091G086T
PhylomeDBiP50880

Family and domain databases

InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

Sequencei

Sequence statusi: Complete.

P50880-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHRKFSAPR HGHMGFTPKK RSRTYRGRIK AFPKDDKSKP IHLTAFLGYK
60 70 80 90 100
AGMTHIVRDV DKPGSKVNKK EVVEAVTIVE TPPMVIAGVT GYVDTPQGPR
110 120 130 140 150
ALTTIWAEHL SEEARRRFYS NWAKSKKKAF TKYAKKWQDE DGKKLIEADF
160 170 180 190 200
AKLKKYCSSI RVIAHTQMKI LRRRQKKAHL VEIQVNGGTI EQKVDWAREH
210 220 230 240 250
LEKQVQVDTV FAQDEMIDTI GVTRGHGFKG VTSRWHTKKL PRKTHKGLRK
260 270 280 290 300
VACIGAWHPS RVAFTVARAG QKGFHHRTII NNKIYRIGKS ALTEEGKNNG
310 320 330 340 350
STEFDLTQKT ITPMGGFPRY GIVNQDYIML RGAVLGPKKR LITLRKSLIT
360 370 380 390 400
QTKRVAHEKI NLKWIDTSSK TGHGRFQTTA EKRAFMGKLK RDFLAEAEAK

A
Length:401
Mass (Da):45,659
Last modified:October 1, 1996 - v1
Checksum:i25F3DAE3714B0DFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69337 Genomic DNA Translation: CAA93269.1
Z69336 mRNA Translation: CAA93268.1
Z49936, Z66495 Genomic DNA Translation: CAA90183.1
PIRiT19771
RefSeqiNP_001021254.1, NM_001026083.4
UniGeneiCel.17929

Genome annotation databases

EnsemblMetazoaiF13B10.2a.1; F13B10.2a.1; WBGene00004414
F13B10.2a.2; F13B10.2a.2; WBGene00004414
GeneIDi175501
KEGGicel:CELE_F13B10.2
UCSCiF13B10.2d.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRL3_CAEEL
AccessioniPrimary (citable) accession number: P50880
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health