Reviewed,
UniProtKB/Swiss-Prot P50864 (CWLD_BACSU)
Last modified
February 9, 2010.
Version 60.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Germination-specific N-acetylmuramoyl-L-alanine amidase EC=3.5.1.28 Alternative name(s): Cell wall hydrolase Autolysin | ||||
| Gene names |
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| Organism | Bacillus subtilis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1423 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 237 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. |
| Subcellular location | Secreted Potential. |
| Sequence similarities | Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell wall biogenesis/degradation |
| Cellular component | Secreted |
| Domain | Signal |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic processInferred from electronic annotation. Source: InterPro |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | N-acetylmuramoyl-L-alanine amidase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Nucleotide sequence and regulation of a new putative cell wall hydrolase gene, cwlD, which affects germination in Bacillus subtilis." Sekiguchi J., Akeo K., Yamamoto H., Khasanov F.K., Alonso J.C., Kuroda A. J. Bacteriol. 177:5582-5589(1995) [PubMed: 7559346] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Sequence analysis of a 50 kb region between spo0H and rrnH on the Bacillus subtilis chromosome." Yasumoto K., Liu H., Jeong S.M., Ohashi Y., Kakinuma S., Tanaka K., Kawamura F., Yoshikawa H., Takahashi H. Microbiology 142:3039-3046(1996) [PubMed: 8969501] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [3] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X74737 Genomic DNA. Translation: CAA52758.1. D64126 Genomic DNA. Translation: BAA10993.1. AL009126 Genomic DNA. Translation: CAB11929.1. |
| PIR | G69610. |
| RefSeq | NP_388034.1. |
3D structure databases | |
| SMR | P50864. Positions 41-232. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 938917. |
| GenomeReviews | Gene locus BSU01530 in contig AL009126_GR. |
| KEGG | bsu:BSU01530. |
| NMPDR | fig|224308.1.peg.153. |
Organism-specific databases | |
| SubtiList | BG11514. cwlD. [Micado] |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG656726. |
| OMA | SVIVECG. |
Enzyme and pathway databases | |
| BRENDA | 3.5.1.28. 150. |
Family and domain databases | |
| InterPro | IPR002508. CW_Hdrlase/autolysin_cat. IPR014234. Spore_cwlD. [Graphical view] |
| Gene3D | G3DSA:3.40.630.40. Cell_wall_OHase/autolysin_cat. 1 hit. |
| Pfam | PF01520. Amidase_3. 1 hit. [Graphical view] |
| SMART | SM00646. Ami_3. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02883. spore_cwlD. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | CWLD_BACSU | ||||||||
| Accession | Primary (citable) accession number: P50864 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| SIMILARITY comments Index of protein domains and families |

Clusters with


