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Reviewed, UniProtKB/Swiss-Prot P50845 (KDGK_BACSU)

Last modified November 3, 2009. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    2-dehydro-3-deoxygluconokinase
    EC=2.7.1.45
Alternative name(s):
    2-keto-3-deoxygluconokinase
    3-deoxy-2-oxo-D-gluconate kinase
    KDG kinase
Gene names
Name: kdgK
Ordered Locus Names: BSU22110
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 6-phospho-2-dehydro-3-deoxy-D-gluconate.

Pathway

Carbohydrate acid metabolism; 2-dehydro-3-deoxy-D-gluconate degradation; D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate: step 1/2.

Sequence similarities

Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular function2-dehydro-3-deoxygluconokinase activity

Inferred from electronic annotation. Source: EC

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3243242-dehydro-3-deoxygluconokinase
PRO_0000080084

Sequences

Sequence LengthMass (Da)Tools
P50845-1 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 6345AAD7AEDA0759

FASTA32435,036
        10         20         30         40         50         60 
MKLDAVTFGE SMAMFYANEY GGLHEVSTFS KGLAGAESNV ACGLARLGFR MGWMSKVGND 

        70         80         90        100        110        120 
QLGTFILQEL KKEGVDVSRV IRSQDENPTG LLLKSKVKEG DPQVTYYRKN SAASTLTTAE 

       130        140        150        160        170        180 
YPRDYFQCAG HLHVTGIPPA LSAEMKDFTY HVMNDMRNAG KTISFDPNVR PSLWPDQATM 

       190        200        210        220        230        240 
VHTINDLAGL ADWFFPGIAE GELLTGEKTP EGIADYYLKK GASFVAIKLG KEGAYFKTGT 

       250        260        270        280        290        300 
SEGFLEGCRV DRVVDTVGAG DGFAVGVISG ILDGLSYKDA VQRGNAIGAL QVQAPGDMDG 

       310        320 
LPTREKLASF LSAQRTVHQK KGDY 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of the Bacillus subtilis chromosome region between the serA and kdg loci cloned in a yeast artificial chromosome."
Sorokin A.V., Azevedo V., Zumstein E., Galleron N., Ehrlich S.D., Serror P.
Microbiology 142:2005-2016(1996) [PubMed: 8760912] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / Marburg.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

Cross-references

Sequence databases

L47838 Genomic DNA. Translation: AAB38479.1.
AL009126 Genomic DNA. Translation: CAB14128.1.
PIRA69648.
RefSeqNP_390093.1.

3D structure databases

HSSPHSSP built from PDB template 1J5V based on UniProtKB Q9WXS2.
ModBaseSearch...

Genome annotation databases

GeneID939058.
GenomeReviewsGene locus BSU22110 in contig AL009126_GR.
KEGGbsu:BSU22110.
NMPDRfig|224308.1.peg.2216.

Organism-specific databases

SubtiListBG11397. kdgK. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMP50845.
OMACELSHEL.

Enzyme and pathway databases

BioCycBSUB224308:BSU2211-MON.
BRENDA2.7.1.45. 150.

Family and domain databases

InterProIPR011611. Carb/pur_kinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
[Graphical view]
PfamPF00294. PfkB. 1 hit.
[Graphical view]
PROSITEPS00583. PFKB_KINASES_1. False negative.
PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKDGK_BACSU
AccessionPrimary (citable) accession number: P50845
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 3, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents