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P50677 (COX3_THEVL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene names
Name:ctaE
OrganismThermosynechococcus vulcanus (Synechococcus vulcanus)
Taxonomic identifier32053 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus

Protein attributes

Sequence length201 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 201201Cytochrome c oxidase subunit 3
PRO_0000183890

Regions

Transmembrane25 – 4521Helical; Potential
Transmembrane65 – 8521Helical; Potential
Transmembrane100 – 12021Helical; Potential
Transmembrane137 – 15721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P50677 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: F92C60DC0A0C0268

FASTA20122,886
        10         20         30         40         50         60 
MQGTVESQGT AIAVDHAHEH PDFRVLGLLV FLISESLMFG GLFAAYLLLR GMHEQWPPEG 

        70         80         90        100        110        120 
TEVELFVPTI NTLILISSSF VIHYGDVAIK KDDVRGMRKW YWITAAMGAV FLGGQVYEYL 

       130        140        150        160        170        180 
TLGYGLRTNV FANCFYVMTG FHGLHVFIGI LLILGVIWRS RRPGHYNAQK HTGVAMAEIY 

       190        200 
WHFVDVIWII LFTLLYILTR F 

« Hide

References

[1]"The genes in the thermophilic cyanobacterium Synechococcus vulcanus encoding cytochrome-c oxidase."
Sone N., Tano H., Ishizuka M.
Biochim. Biophys. Acta 1183:130-138(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D16254 Genomic DNA. Translation: BAA41042.1.

3D structure databases

ProteinModelPortalP50677.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_THEVL
AccessionPrimary (citable) accession number: P50677
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families