true1996-10-012024-01-24104RIR2_EHV4Sequences of the ribonucleotide reductase-encoding genes of equine herpesvirus 4.Riggio M.P.Onions D.E.doi:10.1016/0378-1119(94)90099-x1994Gene143217-222NUCLEOTIDE SEQUENCE [GENOMIC DNA]1942Tinkering with a viral ribonucleotide reductase.Lembo D.Brune W.doi:10.1016/j.tibs.2008.09.0082009Trends Biochem. Sci.3425-32REVIEW2RNRR2Ribonucleotide Reductase, subunit AHSV_RIR2Ferritin-like_SFHSV_RIR2RNR-likeRNR_smallRNR_small_ASRNR_small_famRIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAINRIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2Ribonuc_red_smFerritin-likeRIBORED_SMALLRibonucleoside-diphosphate reductase small subunit1.17.4.1Ribonucleotide reductase small subunitRIR2Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.Heterotetramer composed of a homodimer of the large subunit (R1) and a homodimer of the small subunit (R2). Larger multisubunit protein complex are also active, composed of (R1)n(R2)n.Belongs to the ribonucleoside diphosphate reductase small chain family.Ribonucleoside-diphosphate reductase small subunit361721320Helical16418411477107110170204207121996-10-011361721bf7c2ba48f1a66b2b59f669a02647b8MALENSKKTDFADELLINAYFYTPECPDIEHLRLLSVANRWLDTDLPISDDLKDVAKLAPAEREFYRFLFAFLSAADDLVNLNLGDLSALFTQKDILHYYIEQESIEVTHSRVYSAIQLMLFGNDATARARYVASVVKDVAIDLKVSWLQAKVRECKSVAEKYILMILIEGVFFASSFASIAYLRTHNLFVVTCQSNDLISRDEAIHTNASCCIYNNYLGGFEKPAPTRIYALFSEAVNIECEFLLSHAPKSSHLLDIEAIICYVRYSADRLLGEIGLSPLFNAPKPPPSFPLAFMTVEKHTNFFERRSTAYSGTLINDLtrue