##gff-version 3
P50643	UniProtKB	Chain	1	835	.	.	.	ID=PRO_0000187244;Note=Ribonucleoside-diphosphate reductase large subunit	
P50643	UniProtKB	Region	1	39	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P50643	UniProtKB	Compositional bias	1	24	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P50643	UniProtKB	Active site	489	489	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Active site	491	491	.	.	.	Note=Cysteine radical intermediate;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Active site	493	493	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Binding site	262	262	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Binding site	277	278	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Binding site	308	308	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Binding site	489	493	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Binding site	666	670	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	278	278	.	.	.	Note=Important for hydrogen atom transfer;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	506	506	.	.	.	Note=Important for hydrogen atom transfer;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	810	810	.	.	.	Note=Important for electron transfer;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	811	811	.	.	.	Note=Important for electron transfer;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	830	830	.	.	.	Note=Interacts with thioredoxin/glutaredoxin;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Site	833	833	.	.	.	Note=Interacts with thioredoxin/glutaredoxin;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026	
P50643	UniProtKB	Disulfide bond	278	506	.	.	.	Note=Redox-active;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_04026