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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Tomato bushy stunt virus (strain type) (TBSV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding, Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiTomato bushy stunt virus (strain type) (TBSV)
Taxonomic identifieri70159 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCapsicum annuum (Bell pepper) [TaxID: 4072]
Malus [TaxID: 3749]
Pyrus (pears) [TaxID: 3766]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
Tolmiea menziesii [TaxID: 29777]
Tulipa [TaxID: 13305]

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002228841 – 172RNA silencing suppressor p19Add BLAST172

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP50628
SMRiP50628
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

Gene3Di2.60.40.1810, 1 hit
InterProiView protein in InterPro
IPR004905 Tombusvirus_p19
IPR036131 VP19_sf
PfamiView protein in Pfam
PF03220 Tombus_P19, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005743 Tombus_P19, 1 hit
SUPFAMiSSF103145 SSF103145, 1 hit

Sequencei

Sequence statusi: Complete.

P50628-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAIQGNDA REQANSERWD GGSGSSTSPF QLPDESPSWT EWRLHNDETN
60 70 80 90 100
SNQDNPLGFK ESWGFGKVVF KRYLRYERTE TSLHRVLGSW TGDSVNYAAS
110 120 130 140 150
RFFGVNQIGC TYSIRFRGVS VTISGGSRTL QHLCEMAIRS KQELLQLTPV
160 170
EVESNVSRGC PEGVETFEEE SE
Length:172
Mass (Da):19,421
Last modified:October 1, 1996 - v1
Checksum:iE51E7FB9BA7FAA29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68899 Genomic RNA Translation: CAA93132.1

Similar proteinsi

Entry informationi

Entry nameiP19_TBSVT
AccessioniPrimary (citable) accession number: P50628
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

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