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P50626

- P19_TBSVB

UniProt

P50626 - P19_TBSVB

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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Tomato bushy stunt virus (strain BS-3) (TBSV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiTomato bushy stunt virus (strain BS-3) (TBSV)
Taxonomic identifieri12146 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCapsicum annuum (Bell pepper) [TaxID: 4072]
Malus [TaxID: 3749]
Pyrus (pears) [TaxID: 3766]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
Tolmiea menziesii [TaxID: 29777]
Tulipa [TaxID: 13305]

Subcellular locationi

GO - Cellular componenti

  1. virion Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172RNA silencing suppressor p19PRO_0000222880Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP50626.
SMRiP50626. Positions 9-152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

InterProiIPR004905. Tombusvirus_p19.
[Graphical view]
PfamiPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomiPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103145. SSF103145. 1 hit.

Sequencei

Sequence statusi: Complete.

P50626-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERAIQGNDA REQAYGERWN GGSGSSTSPF KLPDESPSWT EWRLHNDETI
60 70 80 90 100
SNQDNPLGFK ESWGFGKVVF KRYLRYERTE TSLHRVLGSW TGDSVNYAAS
110 120 130 140 150
RFLGFDQIGC TYSIRFRGVS VTISGGSRTL QHLSEMAIRS KQELLQLTPV
160 170
EVESDVSRGC PEGIETFKEE SE
Length:172
Mass (Da):19,451
Last modified:October 1, 1996 - v1
Checksum:i445AF16F16498841
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z68895 Genomic RNA. Translation: CAA93124.1.
Z68900 Genomic RNA. Translation: CAA93134.1.
Z68902 Genomic RNA. Translation: CAA93138.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z68895 Genomic RNA. Translation: CAA93124.1 .
Z68900 Genomic RNA. Translation: CAA93134.1 .
Z68902 Genomic RNA. Translation: CAA93138.1 .

3D structure databases

ProteinModelPortali P50626.
SMRi P50626. Positions 9-152.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004905. Tombusvirus_p19.
[Graphical view ]
Pfami PF03220. Tombus_P19. 1 hit.
[Graphical view ]
ProDomi PD005743. Tombus_P19. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF103145. SSF103145. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Different tomato bushy stunt virus strains cause disease outbreaks on solanaceous crops in Spain."
    Luis-Areteaga M., Rodriguez-Cerezo E., Fraile A., Saez E., Garcia-Arenal F.
    Phytopathology 86:535-542(1996)
    [AGRICOLA] [Europe PMC]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiP19_TBSVB
AccessioniPrimary (citable) accession number: P50626
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3