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P50624

- P19_TBSV8

UniProt

P50624 - P19_TBSV8

Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Tomato bushy stunt virus (strain B8) (TBSV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA By similarity.By similarity

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Suppressor of RNA silencing

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA silencing suppressor p19
    Alternative name(s):
    19 kDa symptom severity modulator
    Gene namesi
    ORF Names:ORF4
    OrganismiTomato bushy stunt virus (strain B8) (TBSV)
    Taxonomic identifieri70155 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
    Virus hostiCapsicum annuum (Bell pepper) [TaxID: 4072]
    Malus [TaxID: 3749]
    Pyrus (pears) [TaxID: 3766]
    Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
    Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
    Tolmiea menziesii [TaxID: 29777]
    Tulipa [TaxID: 13305]

    Subcellular locationi

    GO - Cellular componenti

    1. virion Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 171171RNA silencing suppressor p19PRO_0000222878Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP50624.
    SMRiP50624. Positions 9-152.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tombusvirus protein p19 family.Curated

    Family and domain databases

    InterProiIPR004905. Tombusvirus_p19.
    [Graphical view]
    PfamiPF03220. Tombus_P19. 1 hit.
    [Graphical view]
    ProDomiPD005743. Tombus_P19. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF103145. SSF103145. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P50624-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERAIPGNDT REPAYGERWN GGPGGSTSPF QLPDESPSWT EWRLHYDETN    50
    SNQDNPLGFK ESWGFGKVVF KRYLRYDGTE TSLHRVLGSW TGDSVNYAAS 100
    RFFGFDQIGC TYSIRFRGVS VTISGGSRTL QHLSEMAIRS KQELLQLTPV 150
    QVESDVSRGR PECQTFKEES E 171
    Length:171
    Mass (Da):19,354
    Last modified:October 1, 1996 - v1
    Checksum:iE4FC480FFF62D759
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68897 Genomic RNA. Translation: CAA93128.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68897 Genomic RNA. Translation: CAA93128.1 .

    3D structure databases

    ProteinModelPortali P50624.
    SMRi P50624. Positions 9-152.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR004905. Tombusvirus_p19.
    [Graphical view ]
    Pfami PF03220. Tombus_P19. 1 hit.
    [Graphical view ]
    ProDomi PD005743. Tombus_P19. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF103145. SSF103145. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Different tomato bushy stunt virus strains cause disease outbreaks on solanaceous crops in Spain."
      Luis-Areteaga M., Rodriguez-Cerezo E., Fraile A., Saez E., Garcia-Arenal F.
      Phytopathology 86:535-542(1996)
      [AGRICOLA] [Europe PMC]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiP19_TBSV8
    AccessioniPrimary (citable) accession number: P50624
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3