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P50471

- GSTX1_NICPL

UniProt

P50471 - GSTX1_NICPL

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Protein

Probable glutathione S-transferase MSR-1

Gene

MSR-1

Organism
Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

May play an important role in hormonal and growth regulatory responses.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei14 – 141GlutathioneBy similarity
Binding sitei41 – 411GlutathioneBy similarity
Binding sitei55 – 551Glutathione; via amide nitrogen and carbonyl oxygenBy similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC

GO - Biological processi

  1. auxin-activated signaling pathway Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Auxin signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutathione S-transferase MSR-1 (EC:2.5.1.18)
Alternative name(s):
Auxin-regulated protein MSR-1
Gene namesi
Name:MSR-1
OrganismiNicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Taxonomic identifieri4092 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Probable glutathione S-transferase MSR-1PRO_0000185862Add
BLAST

Expressioni

Inductioni

By auxin and cytokinin.

Structurei

3D structure databases

ProteinModelPortaliP50471.
SMRiP50471. Positions 2-218.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 8380GST N-terminalAdd
BLAST
Domaini89 – 208120GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni67 – 682Glutathione bindingBy similarity

Sequence similaritiesi

Belongs to the GST superfamily. HSP26 family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50471-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESNNVVLLD FSGSSFGMRL RIALALKGIK YEAKEENLSD KSPLLLEMNP
60 70 80 90 100
VHKKIPILIH NGKPICESLN ILEYIDEVWH EKCPLLPSDP YQRSQARFWA
110 120 130 140 150
NYIDNKIYST GRRVWSGKGE DQEEAKKEFI EIFKTLEGEL GNKTYFGGDN
160 170 180 190 200
LGFVDVALVP FTSWFYSYET CANFSIEAEC RKLVVWQNCM ENERVSKSLP
210
HPHKIYDFVL ELKHKLGLA
Length:219
Mass (Da):25,269
Last modified:October 1, 1996 - v1
Checksum:iDCE165B0FB33A759
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S44036 mRNA. Translation: AAB47712.2.
PIRiJQ1606.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S44036 mRNA. Translation: AAB47712.2 .
PIRi JQ1606.

3D structure databases

ProteinModelPortali P50471.
SMRi P50471. Positions 2-218.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cytokinins and auxins control the expression of a gene in Nicotiana plumbaginifolia cells by feedback regulation."
    Dominov J.A., Stenzler L., Lee S., Schwarz J.J., Leisner S., Howell S.H.
    Plant Cell 4:451-461(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiGSTX1_NICPL
AccessioniPrimary (citable) accession number: P50471
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3