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P50471 (GSTX1_NICPL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutathione S-transferase MSR-1

EC=2.5.1.18
Alternative name(s):
Auxin-regulated protein MSR-1
Gene names
Name:MSR-1
OrganismNicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Taxonomic identifier4092 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May play an important role in hormonal and growth regulatory responses.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Induction

By auxin and cytokinin.

Sequence similarities

Belongs to the GST superfamily. HSP26 family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processAuxin signaling pathway
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processauxin-activated signaling pathway

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Probable glutathione S-transferase MSR-1
PRO_0000185862

Regions

Domain4 – 8380GST N-terminal
Domain89 – 208120GST C-terminal
Region67 – 682Glutathione binding By similarity

Sites

Binding site141Glutathione By similarity
Binding site411Glutathione By similarity
Binding site551Glutathione; via amide nitrogen and carbonyl oxygen By similarity

Sequences

Sequence LengthMass (Da)Tools
P50471 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: DCE165B0FB33A759

FASTA21925,269
        10         20         30         40         50         60 
MESNNVVLLD FSGSSFGMRL RIALALKGIK YEAKEENLSD KSPLLLEMNP VHKKIPILIH 

        70         80         90        100        110        120 
NGKPICESLN ILEYIDEVWH EKCPLLPSDP YQRSQARFWA NYIDNKIYST GRRVWSGKGE 

       130        140        150        160        170        180 
DQEEAKKEFI EIFKTLEGEL GNKTYFGGDN LGFVDVALVP FTSWFYSYET CANFSIEAEC 

       190        200        210 
RKLVVWQNCM ENERVSKSLP HPHKIYDFVL ELKHKLGLA 

« Hide

References

[1]"Cytokinins and auxins control the expression of a gene in Nicotiana plumbaginifolia cells by feedback regulation."
Dominov J.A., Stenzler L., Lee S., Schwarz J.J., Leisner S., Howell S.H.
Plant Cell 4:451-461(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S44036 mRNA. Translation: AAB47712.2.
PIRJQ1606.

3D structure databases

ProteinModelPortalP50471.
SMRP50471. Positions 2-218.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTX1_NICPL
AccessionPrimary (citable) accession number: P50471
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families