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P50388

- BGAL_SULSH

UniProt

P50388 - BGAL_SULSH

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Protein
Beta-galactosidase
Gene
bglY
Organism
Sulfolobus shibatae
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei206 – 2061Proton donor Reviewed prediction
Active sitei387 – 3871Nucleophile By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Lactase
Gene namesi
Name:bglY
OrganismiSulfolobus shibatae
Taxonomic identifieri2286 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 489489Beta-galactosidase
PRO_0000063868Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei135 – 1351N6-methyllysine By similarity
Modified residuei273 – 2731N6-methyllysine By similarity
Modified residuei332 – 3321N6-methyllysine By similarity

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliP50388.
SMRiP50388. Positions 1-489.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 2 hits.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50388-1 [UniParc]FASTAAdd to Basket

« Hide

MYSFPKNFRF GWSQAGFQSE MGTPGSEDPN TDWYKWVHDP ENISAGLVSG    50
DLPENGPGYW GNYKTFHDNA QKMGLKIARL NVEWSRIFPN QLPKPQNFDD 100
SKQDVTEVEI NQNELRRLDE HANKDALNHY REIFKDLKSR GIYFILNMYH 150
WPLPLWLHDP IRVRRGDLSG PTGWLSTRTV YEFARFSAYI AWKFDDLVDE 200
YSTMNEPNVV GGLGYVGVKS GFPPGYLSFE LSRKAMYNII QAHARAYDGI 250
KSVSKKPIGI IYANSSFQPL TEKDVEAVEM AEYDNRWAFF DAIIRGEIMR 300
GSEKVVRDDL RGRLDWIGVN YYTRTVVKKT EKGYTSLGGY GHGCERNSVS 350
LAGLPTSDFG WEFFPEGLYD VLTKYWNRYH LYMYVTENGI ADDADYQRPY 400
YLVSHVYQVH RAINSGADVR GYLHWSLADN YEWASGFSMR FGLLKVDYGT 450
KRLYWRPSAL VYREIATNGG ITDEIEHLNT VPPIRPLRH 489
Length:489
Mass (Da):56,565
Last modified:October 1, 1996 - v1
Checksum:i32412B88F478842E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L47841 Genomic DNA. Translation: AAA79030.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L47841 Genomic DNA. Translation: AAA79030.1 .

3D structure databases

ProteinModelPortali P50388.
SMRi P50388. Positions 1-489.
ModBasei Search...

Protein family/group databases

CAZyi GH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10353. PTHR10353. 1 hit.
Pfami PF00232. Glyco_hydro_1. 2 hits.
[Graphical view ]
PRINTSi PR00131. GLHYDRLASE1.
SUPFAMi SSF51445. SSF51445. 1 hit.
PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The development and application of genetical techniques for the extremely thermoacidophilic archaeon Sulfolobus shibatae."
    Connaris H., Charalambous B.M.
    Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12.

Entry informationi

Entry nameiBGAL_SULSH
AccessioniPrimary (citable) accession number: P50388
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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