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P50388 (BGAL_SULSH) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase

Short name=Lactase
EC=3.2.1.23
Gene names
Name:bglY
OrganismSulfolobus shibatae
Taxonomic identifier2286 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Subunit structure

Homotetramer.

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
   PTMMethylation
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 489489Beta-galactosidase
PRO_0000063868

Sites

Active site2061Proton donor Potential
Active site3871Nucleophile By similarity

Amino acid modifications

Modified residue1351N6-methyllysine By similarity
Modified residue2731N6-methyllysine By similarity
Modified residue3321N6-methyllysine By similarity

Sequences

Sequence LengthMass (Da)Tools
P50388 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 32412B88F478842E

FASTA48956,565
        10         20         30         40         50         60 
MYSFPKNFRF GWSQAGFQSE MGTPGSEDPN TDWYKWVHDP ENISAGLVSG DLPENGPGYW 

        70         80         90        100        110        120 
GNYKTFHDNA QKMGLKIARL NVEWSRIFPN QLPKPQNFDD SKQDVTEVEI NQNELRRLDE 

       130        140        150        160        170        180 
HANKDALNHY REIFKDLKSR GIYFILNMYH WPLPLWLHDP IRVRRGDLSG PTGWLSTRTV 

       190        200        210        220        230        240 
YEFARFSAYI AWKFDDLVDE YSTMNEPNVV GGLGYVGVKS GFPPGYLSFE LSRKAMYNII 

       250        260        270        280        290        300 
QAHARAYDGI KSVSKKPIGI IYANSSFQPL TEKDVEAVEM AEYDNRWAFF DAIIRGEIMR 

       310        320        330        340        350        360 
GSEKVVRDDL RGRLDWIGVN YYTRTVVKKT EKGYTSLGGY GHGCERNSVS LAGLPTSDFG 

       370        380        390        400        410        420 
WEFFPEGLYD VLTKYWNRYH LYMYVTENGI ADDADYQRPY YLVSHVYQVH RAINSGADVR 

       430        440        450        460        470        480 
GYLHWSLADN YEWASGFSMR FGLLKVDYGT KRLYWRPSAL VYREIATNGG ITDEIEHLNT 


VPPIRPLRH 

« Hide

References

[1]"The development and application of genetical techniques for the extremely thermoacidophilic archaeon Sulfolobus shibatae."
Connaris H., Charalambous B.M.
Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L47841 Genomic DNA. Translation: AAA79030.1.

3D structure databases

ProteinModelPortalP50388.
SMRP50388. Positions 1-489.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 2 hits.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGAL_SULSH
AccessionPrimary (citable) accession number: P50388
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries