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P50386

- TRPF_SULSO

UniProt

P50386 - TRPF_SULSO

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-848-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:SSO0892
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154415Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0892.

Structurei

3D structure databases

ProteinModelPortaliP50386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
InParanoidiP50386.
KOiK01817.
OMAiHEYLALE.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P50386-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKLKICGNA TLSDIIEFSK LDVDYLGIIT DVVSQRFVKS EFLTFVKRYV
60 70 80 90 100
EKPIVNVKVN VQISEIEREL LVSDYFQIHR VLDDSELELL KSYDFRKRII
110 120 130 140 150
LYVPASFEYK KYLERAIDTV DMVLVDSVKK GVGVDYNVVS SFLKDYPYLG
160 170 180 190 200
VGGKISIDNI SNFIDLNPAW LDISSSIEIY PGKKDINMVK KIVEVVKYGS

SSNK
Length:204
Mass (Da):23,342
Last modified:October 1, 1996 - v1
Checksum:i0697F1FF5D2213BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50014 Genomic DNA. Translation: CAA90310.1.
AE006641 Genomic DNA. Translation: AAK41174.1.
PIRiG90239.
RefSeqiNP_342384.1. NC_002754.1.
WP_009992306.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK41174; AAK41174; SSO0892.
GeneIDi1455141.
KEGGisso:SSO0892.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z50014 Genomic DNA. Translation: CAA90310.1 .
AE006641 Genomic DNA. Translation: AAK41174.1 .
PIRi G90239.
RefSeqi NP_342384.1. NC_002754.1.
WP_009992306.1. NC_002754.1.

3D structure databases

ProteinModelPortali P50386.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273057.SSO0892.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK41174 ; AAK41174 ; SSO0892 .
GeneIDi 1455141.
KEGGi sso:SSO0892.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
InParanoidi P50386.
KOi K01817.
OMAi HEYLALE.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SSOL273057:GCH2-848-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The tryptophan operon in Sulfolobus solfataricus."
    Tutino M.L., Cubellis M., Sannia G., Marino G.
    Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 5833 / MT-4.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiTRPF_SULSO
AccessioniPrimary (citable) accession number: P50386
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3