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P50386

- TRPF_SULSO

UniProt

P50386 - TRPF_SULSO

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, SSO0892
Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-848-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:SSO0892
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_0000154415Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0892.

Structurei

3D structure databases

ProteinModelPortaliP50386.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiHEYLALE.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P50386-1 [UniParc]FASTAAdd to Basket

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MVKLKICGNA TLSDIIEFSK LDVDYLGIIT DVVSQRFVKS EFLTFVKRYV    50
EKPIVNVKVN VQISEIEREL LVSDYFQIHR VLDDSELELL KSYDFRKRII 100
LYVPASFEYK KYLERAIDTV DMVLVDSVKK GVGVDYNVVS SFLKDYPYLG 150
VGGKISIDNI SNFIDLNPAW LDISSSIEIY PGKKDINMVK KIVEVVKYGS 200
SSNK 204
Length:204
Mass (Da):23,342
Last modified:October 1, 1996 - v1
Checksum:i0697F1FF5D2213BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z50014 Genomic DNA. Translation: CAA90310.1.
AE006641 Genomic DNA. Translation: AAK41174.1.
PIRiG90239.
RefSeqiNP_342384.1. NC_002754.1.
WP_009992306.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK41174; AAK41174; SSO0892.
GeneIDi1455141.
KEGGisso:SSO0892.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z50014 Genomic DNA. Translation: CAA90310.1 .
AE006641 Genomic DNA. Translation: AAK41174.1 .
PIRi G90239.
RefSeqi NP_342384.1. NC_002754.1.
WP_009992306.1. NC_002754.1.

3D structure databases

ProteinModelPortali P50386.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273057.SSO0892.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK41174 ; AAK41174 ; SSO0892 .
GeneIDi 1455141.
KEGGi sso:SSO0892.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi HEYLALE.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SSOL273057:GCH2-848-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The tryptophan operon in Sulfolobus solfataricus."
    Tutino M.L., Cubellis M., Sannia G., Marino G.
    Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 5833 / MT-4.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiTRPF_SULSO
AccessioniPrimary (citable) accession number: P50386
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 3, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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