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P50386

- TRPF_SULSO

UniProt

P50386 - TRPF_SULSO

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSSOL273057:GCH2-848-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:trpF
    Ordered Locus Names:SSO0892
    OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
    Taxonomic identifieri273057 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
    ProteomesiUP000001974: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 204204N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154415Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273057.SSO0892.

    Structurei

    3D structure databases

    ProteinModelPortaliP50386.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiHEYLALE.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P50386-1 [UniParc]FASTAAdd to Basket

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    MVKLKICGNA TLSDIIEFSK LDVDYLGIIT DVVSQRFVKS EFLTFVKRYV    50
    EKPIVNVKVN VQISEIEREL LVSDYFQIHR VLDDSELELL KSYDFRKRII 100
    LYVPASFEYK KYLERAIDTV DMVLVDSVKK GVGVDYNVVS SFLKDYPYLG 150
    VGGKISIDNI SNFIDLNPAW LDISSSIEIY PGKKDINMVK KIVEVVKYGS 200
    SSNK 204
    Length:204
    Mass (Da):23,342
    Last modified:October 1, 1996 - v1
    Checksum:i0697F1FF5D2213BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z50014 Genomic DNA. Translation: CAA90310.1.
    AE006641 Genomic DNA. Translation: AAK41174.1.
    PIRiG90239.
    RefSeqiNP_342384.1. NC_002754.1.
    WP_009992306.1. NC_002754.1.

    Genome annotation databases

    EnsemblBacteriaiAAK41174; AAK41174; SSO0892.
    GeneIDi1455141.
    KEGGisso:SSO0892.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z50014 Genomic DNA. Translation: CAA90310.1 .
    AE006641 Genomic DNA. Translation: AAK41174.1 .
    PIRi G90239.
    RefSeqi NP_342384.1. NC_002754.1.
    WP_009992306.1. NC_002754.1.

    3D structure databases

    ProteinModelPortali P50386.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273057.SSO0892.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK41174 ; AAK41174 ; SSO0892 .
    GeneIDi 1455141.
    KEGGi sso:SSO0892.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi HEYLALE.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SSOL273057:GCH2-848-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The tryptophan operon in Sulfolobus solfataricus."
      Tutino M.L., Cubellis M., Sannia G., Marino G.
      Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: DSM 5833 / MT-4.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

    Entry informationi

    Entry nameiTRPF_SULSO
    AccessioniPrimary (citable) accession number: P50386
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3