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Protein

Phosphoglycerate kinase, plasmid

Gene

cbbKP

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathway: Calvin cycle

This protein is involved in the pathway Calvin cycle, which is part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the pathway Calvin cycle and in Carbohydrate biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei55 – 551SubstrateBy similarity
Binding sitei133 – 1331SubstrateBy similarity
Binding sitei166 – 1661SubstrateBy similarity
Binding sitei217 – 2171ATPBy similarity
Binding sitei339 – 3391ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi365 – 3684ATPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Calvin cycle

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCNEC381666:GJUJ-6691-MONOMER.
UniPathwayiUPA00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase, plasmid (EC:2.7.2.3)
Gene namesi
Name:cbbKP
Ordered Locus Names:PHG417
Encoded oniPlasmid megaplasmid pHG10 Publication
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000008210 Componenti: Plasmid megaplasmid pHG1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Phosphoglycerate kinase, plasmidPRO_0000145896Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi381666.H16_B1385.

Structurei

3D structure databases

ProteinModelPortaliP50320.
SMRiP50320. Positions 29-410.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni39 – 413Substrate bindingBy similarity
Regioni78 – 814Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiKMANDCI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50320-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSLSHASVP HTNPTAPHTL AALLAAGGLA GKRVFIRADL NVPQDAAGDI
60 70 80 90 100
TDDTRIRASV PAIAACLQAG AAVMVTSHLG RPQEGAPDPR HSLAPVGRRL
110 120 130 140 150
SELLGRQVPL LSGWTEGGFQ VPPGQVVLLE NCRMNTGEKK NSDELAQKMA
160 170 180 190 200
ALCDVYVNDA FGTAHRAEAT THGIARYAPV ACAGPLLAAE IDALGKALGQ
210 220 230 240 250
PARPLVAIVA GSKVSTKLTI LKSLADKVDN LVVGGGIANT FMLAAGLKIG
260 270 280 290 300
KSLAEPDLLA DARAIIDIMA ARGASVPIPV DVVCAKEFSA TAAAAVKDVR
310 320 330 340 350
DVADDDMILD IGPKTAAMLA DQLKAAGTIV WNGPVGVFEF DQFGNGTRVL
360 370 380 390 400
AQAIAESKAF SIAGGGDTLA AIAKYGIADR VGYISTGGGA FLEFLEGKKL
410
PALDVLEQRA AS
Length:412
Mass (Da):42,299
Last modified:October 1, 1996 - v1
Checksum:i9E84C666859E7274
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12423 Genomic DNA. Translation: AAC43447.1.
AY305378 Genomic DNA. Translation: AAP86166.1.
PIRiI39554.
RefSeqiNP_943052.1. NC_005241.1.
WP_011154329.1. NG_034711.1.
YP_009074643.1. NG_034711.1.

Genome annotation databases

EnsemblBacteriaiAAP86166; AAP86166; PHG417.
KEGGireh:PHG417.
PATRICi35229346. VBIRalEut6770_0345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12423 Genomic DNA. Translation: AAC43447.1.
AY305378 Genomic DNA. Translation: AAP86166.1.
PIRiI39554.
RefSeqiNP_943052.1. NC_005241.1.
WP_011154329.1. NG_034711.1.
YP_009074643.1. NG_034711.1.

3D structure databases

ProteinModelPortaliP50320.
SMRiP50320. Positions 29-410.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi381666.H16_B1385.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP86166; AAP86166; PHG417.
KEGGireh:PHG417.
PATRICi35229346. VBIRalEut6770_0345.

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiKMANDCI.
OrthoDBiEOG64N9Z0.

Enzyme and pathway databases

UniPathwayiUPA00116.
BioCyciCNEC381666:GJUJ-6691-MONOMER.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the genes forming the distal parts of the two cbb CO2 fixation operons from Alcaligenes eutrophus."
    Schaeferfohann J., Yoo J.-G., Bowien B.
    Arch. Microbiol. 163:291-299(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete nucleotide sequence of pHG1: a Ralstonia eutropha H16 megaplasmid encoding key enzymes of H(2)-based lithoautotrophy and anaerobiosis."
    Schwartz E., Henne A., Cramm R., Eitinger T., Friedrich B., Gottschalk G.
    J. Mol. Biol. 332:369-383(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Entry informationi

Entry nameiPGKP_CUPNH
AccessioniPrimary (citable) accession number: P50320
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 24, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.