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P50319 (PGKC_CUPNH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase, chromosomal

EC=2.7.2.3
Gene names
Name:cbbKC
Synonyms:cbbK2
Ordered Locus Names:H16_B1385
OrganismCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) [Complete proteome] [HAMAP]
Taxonomic identifier381666 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

Protein attributes

Sequence length413 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate biosynthesis; Calvin cycle. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processCalvin cycle
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

reductive pentose-phosphate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 413413Phosphoglycerate kinase, chromosomal HAMAP-Rule MF_00145
PRO_0000145895

Regions

Nucleotide binding366 – 3694ATP By similarity
Region40 – 423Substrate binding By similarity
Region79 – 824Substrate binding By similarity

Sites

Binding site561Substrate By similarity
Binding site1341Substrate By similarity
Binding site1671Substrate By similarity
Binding site2181ATP By similarity
Binding site3401ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P50319 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 6B4C9D195566A90D

FASTA41342,284
        10         20         30         40         50         60 
MMSLSHATNP QPKPAAAPHT LAALLAAGGL AGKRVFIRAD LNVPQDAAGA ITDDTRIRAS 

        70         80         90        100        110        120 
VPAIAACLQA GAAVMVTSHL GRPQEGAPDP RHSLAPVGRR LSELLGRQVP LLSGWTEGGF 

       130        140        150        160        170        180 
QVPPGQVVLL ENCRMNTGEK KNSDELAQKM AALCDVYVND AFGTAHRAEA TTHGIARYAP 

       190        200        210        220        230        240 
IACAGPLLAA EIDALGKALG QPARPLVAIV AGSKVSTKLT ILKSLADKVD NLIVGGGIAN 

       250        260        270        280        290        300 
TFMLAAGLKI GKSLAEPDLL ADARAIIDIM ARRGASVPIP VDVVCAKEFS ATAAATVKDV 

       310        320        330        340        350        360 
KDVADDDMIL DIGPKTAAML AEQLKAAGTI VWNGPVGVFE FDQFGNGTRV LAQAIAESKA 

       370        380        390        400        410 
FSIAGGGDTL AAIAKHGIAD RVGYISTGGG AFLEFLEGKT LPALAVLAQR AAA 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the genes forming the distal parts of the two cbb CO2 fixation operons from Alcaligenes eutrophus."
Schaeferfohann J., Yoo J.-G., Bowien B.
Arch. Microbiol. 163:291-299(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16."
Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R., Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I., Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.
Nat. Biotechnol. 24:1257-1262(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U12422 Genomic DNA. Translation: AAC43444.1.
AM260480 Genomic DNA. Translation: CAJ96174.1.
PIRI39551.
RefSeqYP_840904.1. NC_008314.1.

3D structure databases

ProteinModelPortalP50319.
SMRP50319. Positions 30-411.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING381666.H16_B1385.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ96174; CAJ96174; H16_B1385.
GeneID4455911.
KEGGreh:H16_B1385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAESNKNHA.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycCNEC381666:GJUJ-5090-MONOMER.
UniPathwayUPA00116.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGKC_CUPNH
AccessionPrimary (citable) accession number: P50319
Secondary accession number(s): Q0K1F0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways