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P50319

- PGKC_CUPNH

UniProt

P50319 - PGKC_CUPNH

Protein

Phosphoglycerate kinase, chromosomal

Gene

cbbKC

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei56 – 561SubstrateBy similarity
    Binding sitei134 – 1341SubstrateBy similarity
    Binding sitei167 – 1671SubstrateBy similarity
    Binding sitei218 – 2181ATPBy similarity
    Binding sitei340 – 3401ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi366 – 3694ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP
    2. reductive pentose-phosphate cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Calvin cycle

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCNEC381666:GJUJ-5090-MONOMER.
    UniPathwayiUPA00116.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase, chromosomal (EC:2.7.2.3)
    Gene namesi
    Name:cbbKC
    Synonyms:cbbK2
    Ordered Locus Names:H16_B1385
    OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
    Taxonomic identifieri381666 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
    ProteomesiUP000008210: Chromosome 2

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 413413Phosphoglycerate kinase, chromosomalPRO_0000145895Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi381666.H16_B1385.

    Structurei

    3D structure databases

    ProteinModelPortaliP50319.
    SMRiP50319. Positions 30-411.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni40 – 423Substrate bindingBy similarity
    Regioni79 – 824Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiIGARTHT.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P50319-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMSLSHATNP QPKPAAAPHT LAALLAAGGL AGKRVFIRAD LNVPQDAAGA    50
    ITDDTRIRAS VPAIAACLQA GAAVMVTSHL GRPQEGAPDP RHSLAPVGRR 100
    LSELLGRQVP LLSGWTEGGF QVPPGQVVLL ENCRMNTGEK KNSDELAQKM 150
    AALCDVYVND AFGTAHRAEA TTHGIARYAP IACAGPLLAA EIDALGKALG 200
    QPARPLVAIV AGSKVSTKLT ILKSLADKVD NLIVGGGIAN TFMLAAGLKI 250
    GKSLAEPDLL ADARAIIDIM ARRGASVPIP VDVVCAKEFS ATAAATVKDV 300
    KDVADDDMIL DIGPKTAAML AEQLKAAGTI VWNGPVGVFE FDQFGNGTRV 350
    LAQAIAESKA FSIAGGGDTL AAIAKHGIAD RVGYISTGGG AFLEFLEGKT 400
    LPALAVLAQR AAA 413
    Length:413
    Mass (Da):42,284
    Last modified:October 1, 1996 - v1
    Checksum:i6B4C9D195566A90D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12422 Genomic DNA. Translation: AAC43444.1.
    AM260480 Genomic DNA. Translation: CAJ96174.1.
    PIRiI39551.
    RefSeqiWP_011617201.1. NC_008314.1.
    YP_840904.1. NC_008314.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ96174; CAJ96174; H16_B1385.
    GeneIDi4455911.
    KEGGireh:H16_B1385.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12422 Genomic DNA. Translation: AAC43444.1 .
    AM260480 Genomic DNA. Translation: CAJ96174.1 .
    PIRi I39551.
    RefSeqi WP_011617201.1. NC_008314.1.
    YP_840904.1. NC_008314.1.

    3D structure databases

    ProteinModelPortali P50319.
    SMRi P50319. Positions 30-411.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 381666.H16_B1385.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ96174 ; CAJ96174 ; H16_B1385 .
    GeneIDi 4455911.
    KEGGi reh:H16_B1385.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi IGARTHT.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00116 .
    BioCyci CNEC381666:GJUJ-5090-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the genes forming the distal parts of the two cbb CO2 fixation operons from Alcaligenes eutrophus."
      Schaeferfohann J., Yoo J.-G., Bowien B.
      Arch. Microbiol. 163:291-299(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

    Entry informationi

    Entry nameiPGKC_CUPNH
    AccessioniPrimary (citable) accession number: P50319
    Secondary accession number(s): Q0K1F0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3