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Protein

Phosphoglycerate kinase, chromosomal

Gene

cbbKC

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi: Calvin cycle

This protein is involved in the pathway Calvin cycle, which is part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the pathway Calvin cycle and in Carbohydrate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei56SubstrateBy similarity1
Binding sitei134SubstrateBy similarity1
Binding sitei167SubstrateBy similarity1
Binding sitei218ATPBy similarity1
Binding sitei340ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi366 – 369ATPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Calvin cycle

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase, chromosomal (EC:2.7.2.3)
Gene namesi
Name:cbbKC
Synonyms:cbbK2
Ordered Locus Names:H16_B1385
OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Taxonomic identifieri381666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000008210 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001458951 – 413Phosphoglycerate kinase, chromosomalAdd BLAST413

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi381666.H16_B1385.

Structurei

3D structure databases

ProteinModelPortaliP50319.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni40 – 42Substrate bindingBy similarity3
Regioni79 – 82Substrate bindingBy similarity4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiENOG4105BZA. Bacteria.
COG0126. LUCA.
HOGENOMiHOG000227107.
KOiK00927.
OMAiSITYLSG.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P50319-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSLSHATNP QPKPAAAPHT LAALLAAGGL AGKRVFIRAD LNVPQDAAGA
60 70 80 90 100
ITDDTRIRAS VPAIAACLQA GAAVMVTSHL GRPQEGAPDP RHSLAPVGRR
110 120 130 140 150
LSELLGRQVP LLSGWTEGGF QVPPGQVVLL ENCRMNTGEK KNSDELAQKM
160 170 180 190 200
AALCDVYVND AFGTAHRAEA TTHGIARYAP IACAGPLLAA EIDALGKALG
210 220 230 240 250
QPARPLVAIV AGSKVSTKLT ILKSLADKVD NLIVGGGIAN TFMLAAGLKI
260 270 280 290 300
GKSLAEPDLL ADARAIIDIM ARRGASVPIP VDVVCAKEFS ATAAATVKDV
310 320 330 340 350
KDVADDDMIL DIGPKTAAML AEQLKAAGTI VWNGPVGVFE FDQFGNGTRV
360 370 380 390 400
LAQAIAESKA FSIAGGGDTL AAIAKHGIAD RVGYISTGGG AFLEFLEGKT
410
LPALAVLAQR AAA
Length:413
Mass (Da):42,284
Last modified:October 1, 1996 - v1
Checksum:i6B4C9D195566A90D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12422 Genomic DNA. Translation: AAC43444.1.
AM260480 Genomic DNA. Translation: CAJ96174.1.
PIRiI39551.

Genome annotation databases

EnsemblBacteriaiCAJ96174; CAJ96174; H16_B1385.
KEGGireh:H16_B1385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12422 Genomic DNA. Translation: AAC43444.1.
AM260480 Genomic DNA. Translation: CAJ96174.1.
PIRiI39551.

3D structure databases

ProteinModelPortaliP50319.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi381666.H16_B1385.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAJ96174; CAJ96174; H16_B1385.
KEGGireh:H16_B1385.

Phylogenomic databases

eggNOGiENOG4105BZA. Bacteria.
COG0126. LUCA.
HOGENOMiHOG000227107.
KOiK00927.
OMAiSITYLSG.

Enzyme and pathway databases

UniPathwayiUPA00116.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPGKC_CUPNH
AccessioniPrimary (citable) accession number: P50319
Secondary accession number(s): Q0K1F0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.